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Danazol chemical structure, C22H27NO2, CAS 17230-88-5
2D chemical structure

Key facts

What buyers check first

CAS number
17230-88-5
Formula
C22H27NO2
Molar mass
337.46 g/mol
EC number
241-270-1
HS code
293723
Category
Hormones and steroids

What is Danazol?

Plain description, key identifiers and synonyms

Danazol is a 17beta-hydroxy steroid and a terminal acetylenic compound. It has a role as a geroprotector, an anti-estrogen and an estrogen antagonist. It derives from a hydride of a pregnane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
CAS number
17230-88-5 CAS number cross-checked
EC number
241-270-1
Molecular formula
C22H27NO2
UNII
N29QWW3BUO
MDL number
MFCD00056838
InChIKey
POZRVZJJTULAOH-LHZXLZLDSA-N
InChI
InChI=1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20+,21+,22+/m1/s1
Canonical SMILES
C#CC1(O)CCC2C3CCC4=Cc5oncc5CC4(C)C3CCC21C
Isomeric SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5

Synonyms

  • Danocrine
  • Chronogyn
  • Danol
  • Winobanin
  • Danazolum
  • Cyclomen
  • Ladogal
  • Bonzol
  • Danatrol
  • WIN 17757
  • WIN 17,757
  • 17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
  • Danoval
  • Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,(17alpha)-
  • (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5,9-trien-17-ol
  • Danazol Ratiopharm
  • (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo(11.7.0.0^(2,10).0^(4,8).0^(14,18))icosa-4(8),5,9-trien-17-ol
  • (17alpha)-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
  • (17Alpha)-pregna-2,4-dien-20-yno(2,3-d)-isoxazol-17-ol
  • 17Alpha-ethynyl-17beta-hydroxy-4-androsteno(2,3-d)isoxazole
  • 1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental(7,8)phenanthro(3,2-d)isoxazol-1-ol
  • Danazol, USP
  • (1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
  • Danazole
  • Danzol
Show all 37 synonyms
  • Danovaol
  • (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
  • Danokrin
  • Danogen
  • Danazol (1.0 mg/mL in acetonitrile)
  • Danocrine (TN)
  • (1R,3aS,3bR,10aR,10bS,12aS)-1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d][1,2]oxazol-1-ol
  • Vasaloc
  • 17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol
  • Optina
  • 17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol
  • Danazol?

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
337.46 g/molcalc.
Exact mass
337.2042 Dacalc.
LogP (octanol/water)
4.22calc.
Topological polar surface area
46.26 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
25calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.68calc.
Formal charge
0calc.
Stereocentres
6calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=C2CCC3C4CCCC4CCC3C2Cc2cnoc21

C1=C2CCC3C4CCCC4CCC3C2Cc2cnoc21

5 rings, 20 atoms.

10 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
  • H351Suspected of causing cancer.
  • H360May damage fertility or the unborn child.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (12)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Danazol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 68 suppliers
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  • United StatesUnclaimed profile
    DanazolGrade, purity and minimum order on request
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  • India, Ahmedabad ManufacturerUnclaimed profile
    DanocrineGrade, purity and minimum order on request
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  • India, Bengaluru ManufacturerUnclaimed profile
    DanazolGrade Pharma (USP)
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  • France, Paris ManufacturerUnclaimed profile
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  • India, Ahmedabad ManufacturerUnclaimed profile
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  • Bangladesh, Dhaka ManufacturerUnclaimed profile
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  • United States, GardenaUnclaimed profile
    DanazolGrade, purity and minimum order on request
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  • India, Sonipat ManufacturerUnclaimed profile
    DanazolGrade, purity and minimum order on request
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  • Mexico, Ixtaczoquitlan Veracruz ManufacturerUnclaimed profile
    DanazolGrade, purity and minimum order on request
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  • United States, PlattsburghUnclaimed profile
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

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Danazol price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Estrogen Antagonists

Roles

  • antagonist
  • anti-anaemic agent
  • anti-estrogen
  • antineoplastic agent
  • estrogen antagonist
  • geroprotector
  • hormone antagonist
  • hormone receptor modulator
  • pharmaceutical
  • protective agent
  • receptor modulator

Pharmacology

Danazol is an Androgen. The mechanism of action of danazol is as an Androgen Receptor Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Danazol is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Danazol is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Danazol, based on the data on this page

What is Danazol?

Danazol is a 17beta-hydroxy steroid and a terminal acetylenic compound. It has a role as a geroprotector, an anti-estrogen and an estrogen antagonist. It derives from a hydride of a pregnane.

What is the CAS number of Danazol?

The CAS registry number of Danazol is 17230-88-5.

What is the molecular formula and weight of Danazol?

The molecular formula of Danazol is C22H27NO2 and its molar mass is 337.46 g/mol.

What is Danazol used for?

Use classes: Pharmaceuticals.

Is Danazol hazardous?

Danazol carries the GHS signal word "Danger". Main hazards: harmful in contact with skin, harmful if inhaled, suspected of causing cancer. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Danazol?

Danazol is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Danazol?

CompoundList lists 68 suppliers of Danazol in United States, China, India, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Danazol in India?

12 suppliers in India list Danazol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Danazol?

Suppliers quote Danazol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Danazol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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