Danazol
Also known as Danocrine, Chronogyn, Danol
Key facts
What buyers check first
- CAS number
- 17230-88-5
- Formula
- C22H27NO2
- Molar mass
- 337.46 g/mol
- EC number
- 241-270-1
- HS code
- 293723
- Category
- Hormones and steroids
What is Danazol?
Plain description, key identifiers and synonyms
Danazol is a 17beta-hydroxy steroid and a terminal acetylenic compound. It has a role as a geroprotector, an anti-estrogen and an estrogen antagonist. It derives from a hydride of a pregnane.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
- CAS number
- 17230-88-5 CAS number cross-checked
- EC number
- 241-270-1
- Molecular formula
- C22H27NO2
- UNII
- N29QWW3BUO
- MDL number
- MFCD00056838
- InChIKey
- POZRVZJJTULAOH-LHZXLZLDSA-N
- InChI
- InChI=1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20+,21+,22+/m1/s1
- Canonical SMILES
- C#CC1(O)CCC2C3CCC4=Cc5oncc5CC4(C)C3CCC21C
- Isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC5=C(C[C@]34C)C=NO5
Synonyms
- Danocrine
- Chronogyn
- Danol
- Winobanin
- Danazolum
- Cyclomen
- Ladogal
- Bonzol
- Danatrol
- WIN 17757
- WIN 17,757
- 17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
- Danoval
- Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,(17alpha)-
- (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5,9-trien-17-ol
- Danazol Ratiopharm
- (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo(11.7.0.0^(2,10).0^(4,8).0^(14,18))icosa-4(8),5,9-trien-17-ol
- (17alpha)-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
- (17Alpha)-pregna-2,4-dien-20-yno(2,3-d)-isoxazol-17-ol
- 17Alpha-ethynyl-17beta-hydroxy-4-androsteno(2,3-d)isoxazole
- 1-Ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-1H-cyclopental(7,8)phenanthro(3,2-d)isoxazol-1-ol
- Danazol, USP
- (1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
- Danazole
- Danzol
Show all 37 synonymsShow fewer synonyms
- Danovaol
- (1S,2R,13R,14S,17R,18S)-17-ethynyl-2,18-dimethyl-7-oxa-6-azapentacyclo[11.7.0.02,10.04,8.014,18]icosa-4(8),5,9-trien-17-ol
- Danokrin
- Danogen
- Danazol (1.0 mg/mL in acetonitrile)
- Danocrine (TN)
- (1R,3aS,3bR,10aR,10bS,12aS)-1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d][1,2]oxazol-1-ol
- Vasaloc
- 17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol
- Optina
- 17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol
- Danazol?
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 337.46 g/molcalc.Computed value |
|---|---|
| Exact mass | 337.2042 Dacalc.Computed value |
| LogP (octanol/water) | 4.22calc.Computed value |
| Topological polar surface area | 46.26 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 3calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 25calc.Computed value |
| Rings | 5calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.68calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 6calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H312Harmful in contact with skin.
- H332Harmful if inhaled.
- H351Suspected of causing cancer.
- H360May damage fertility or the unborn child.
- H361Suspected of damaging fertility or the unborn child.
Precautionary statements (12)
- P203Obtain, read and follow all safety instructions before use.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P317Get medical help.
- P318If exposed or concerned, get medical advice.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidDanazol suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Price on request
- India, Ahmedabad ManufacturerUnclaimed profileDanocrineGrade, purity and minimum order on requestPrice on request
- Price on request
- France, Paris ManufacturerUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
- India, Ahmedabad ManufacturerUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
- Bangladesh, Dhaka ManufacturerUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
- United States, GardenaUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
- India, Sonipat ManufacturerUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
- Mexico, Ixtaczoquitlan Veracruz ManufacturerUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
- United States, PlattsburghUnclaimed profileDanazolGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
68 suppliers in 13 countries
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Danazol price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Estrogen Antagonists
Roles
- antagonist
- anti-anaemic agent
- anti-estrogen
- antineoplastic agent
- estrogen antagonist
- geroprotector
- hormone antagonist
- hormone receptor modulator
- pharmaceutical
- protective agent
- receptor modulator
Pharmacology
Danazol is an Androgen. The mechanism of action of danazol is as an Androgen Receptor Agonist.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Danazol is traded under.
Oestrogens and progestogens
- China42.9%
- Italy18.4%
- Netherlands8.9%
- India * partner reported12.1%
- United States11.0%
- Belgium8.3%
* Partner reported figures, a lower bound.
The HS code shown for Danazol is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Danazol, based on the data on this page
What is Danazol?
What is the CAS number of Danazol?
What is the molecular formula and weight of Danazol?
What is Danazol used for?
Is Danazol hazardous?
What is the HS code of Danazol?
Where can I buy Danazol?
Where can I buy Danazol in India?
What is the price of Danazol?
Guides for buyers
Practical guides that help when you source, ship or handle Danazol
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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