Dextromoramide (CAS 357-56-2): price, suppliers and safety

What is Dextromoramide?

Plain description, key identifiers and synonyms

Dextromoramide is an N-acylpyrrolidine arising by formal condensation of pyrrolidine with (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenylbutanoic acid. An opioid analgesic that is structurally related to methadone, it is more poweful than morphine but shorter acting. It has been used (particularly as the hydrogen tartrate salt) for the treatment of severe pain, but was discontinued in the UK in 2004. It has a role as an opioid analgesic. It is a member of morpholines and a N-acylpyrrolidine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name: (3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one
CAS number: 357-56-2 CAS number cross-checkedOther or deprecated CAS: 13013-15-5
EC number: 206-613-1
Molecular formula: C₂₅H₃₂N₂O₂
UNII: 9S4S6CIY83
InChIKey: INUNXTSAACVKJS-OAQYLSRUSA-N
InChI: InChI=1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3/t21-/m1/s1
Canonical SMILES: CC(CN1CCOCC1)C(C(=O)N1CCCC1)(c1ccccc1)c1ccccc1
Isomeric SMILES: C[C@H](CN1CCOCC1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N4CCCC4

Synonyms

Pyrrolamidol
Pyrrolamidolum
Moramide
Dextromoramida
Dextromoramidum
Linfadol
Palfadonna
Palphium
Troxilan
Alcoid
Jetrium
Narcolo
Yetrium
SKF 5137
Racemoramide, (s)-
(+)-2,2-Diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine
Acscn-9613
(3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one
(+)-1-(3-methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine
D Moramide
D-2,2-diphenyl-3-methyl-4-morpholinobutyrylpyrrolidine
(+)-4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine
4-(2-methyl-4-oxo-3,3-diphenyl-4-(1-pyrrolidinyl)butyl)morpholine
1-((3S)-3-methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)pyrrolidine
Pyrrolidine, 1-(3-methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)-, (S)-

Show all 34 synonyms

D-Moramide
Palfium
Dauran
Jetrium R
(3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one
MCP 875
Destromoramide
(+)-3-methyl-4-morpholino-2,2-diphenyl-1-(pyrrolidin-1-yl)butanone
Pyrrolidine, 1-(2,2-diphenyl-3-methyl-4-morpholinobutyryl)-, (+)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight	392.54 g/molcalc.
Exact mass	392.2464 Dacalc.
LogP (octanol/water)	3.56calc.
Topological polar surface area	32.78 Å²calc.
Hydrogen bond donors	0calc.
Hydrogen bond acceptors	3calc.
Rotatable bonds	6calc.
Heavy atoms	29calc.
Rings	4calc.
Aromatic rings	2calc.
Fraction sp3 carbons	0.48calc.
Formal charge	0calc.
Stereocentres	1calc.
Lipinski rule of five	Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

O=C(N1CCCC1)C(CCN1CCOCC1)(c1ccccc1)c1ccccc1

4 rings, 28 atoms, the Desmethylmoramide ring system.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Dextromoramide suppliers

Trading restrictions apply to this substance

Psychotropic substance

Dextromoramide is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2934.91 (sufentanil and related controlled substances)

Our policy on controlled substances

Dextromoramide price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

Analgesics, Opioid
Narcotics

Roles

analgesic
opioid analgesic
pharmaceutical

Functional uses

Pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Dextromoramide is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2934.91 (sufentanil and related controlled substances)

Our policy on controlled substances

Controls

US DEA controlled substance or listed chemical
Controlled psychotropic substance

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dextromoramide is traded under.

HS 2934.91Exact HS code

Aminorex (INN), brotizolam (INN), clotiazepam (INN), cloxazolam (INN), dextromoramide…

World exports in 2024

$18.8M

−15.2% vs 2023, imports $18.8M

2019 to 2024

Top exporters

Italy26.7%
United States25.5%
India * partner reported21.1%

Top importers

Egypt42.6%
Japan11.0%
Denmark6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dextromoramide is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Parent and salt forms, stereoisomers, similar structures and isomers

Salt and hydrate forms

Records that share this compound as their parent

1-Butanone, 3-methyl-4-(4-morpholinyl)-2,2-diphenyl-1-(1-pyrrolidinyl)-, (3S)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) chemical structure, C29H38N2O8, CAS 2922-44-3

1-Butanone, 3-methyl-4-(4-morpholinyl)-2,2-diphenyl-1-(1-pyrrolidinyl)-, (3S)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)2922-44-3C₂₉H₃₈N₂O₈

Dextromoramide D-tartrate chemical structure, C29H38N2O8, CAS 23071-04-7

Dextromoramide D-tartrate23071-04-7C₂₉H₃₈N₂O₈

Stereoisomers and isotopic forms

Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)

Racemoramide chemical structure, C25H32N2O2, CAS 545-59-5

Racemoramide545-59-5C₂₅H₃₂N₂O₂

1-((3R)-3-Methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)pyrrolidine chemical structure, C25H32N2O2, CAS 5666-11-5

1-((3R)-3-Methyl-4-(4-morpholinyl)-1-oxo-2,2-diphenylbutyl)pyrrolidine5666-11-5C₂₅H₃₂N₂O₂

Same formula isomers

Different compounds that share this molecular formula

All isomers

ZK 119010 chemical structure, C25H32N2O2, CAS 127451-69-8

ZK 119010127451-69-8C₂₅H₃₂N₂O₂

3H-Indolium, 2-[2-[4-(diethylamino)phenyl]ethenyl]-1,3,3-trimethyl-, acetate (1:1) chemical structure, C25H32N2O2, CAS 64346-30-1

3H-Indolium, 2-[2-[4-(diethylamino)phenyl]ethenyl]-1,3,3-trimethyl-, acetate (1:1)64346-30-1C₂₅H₃₂N₂O₂

Rmi 11002 chemical structure, C25H32N2O2, CAS 66686-30-4

Rmi 1100266686-30-4C₂₅H₃₂N₂O₂

Methanone, (4-(3-((1,1-dimethylethyl)amino)propoxy)phenyl)(2-(1-methylethyl)-3-indolizinyl)- chemical structure, C25H32N2O2, CAS 89622-90-2

Methanone, (4-(3-((1,1-dimethylethyl)amino)propoxy)phenyl)(2-(1-methylethyl)-3-indolizinyl)-89622-90-2C₂₅H₃₂N₂O₂

4-(3-(1,2-Dihydro-6-methoxynaphthalen-4-yl)-n-propyl)-1-(2-methoxyphenyl)piperazine chemical structure, C25H32N2O2, CAS 153526-61-5

4-(3-(1,2-Dihydro-6-methoxynaphthalen-4-yl)-n-propyl)-1-(2-methoxyphenyl)piperazine153526-61-5C₂₅H₃₂N₂O₂

4-(3-(1,2-Dihydro-8-methoxynaphthalen-4-yl)-n-propyl)-1-(2-pyridyl)piperazine chemical structure, C25H32N2O2, CAS 153526-67-1

4-(3-(1,2-Dihydro-8-methoxynaphthalen-4-yl)-n-propyl)-1-(2-pyridyl)piperazine153526-67-1C₂₅H₃₂N₂O₂

N-(1-Cyclopentanecarbonyl-2,3-dihydro-1H-indol-6-yl)adamantane-1-carboxamide chemical structure, C25H32N2O2, CAS 1058428-45-7

N-(1-Cyclopentanecarbonyl-2,3-dihydro-1H-indol-6-yl)adamantane-1-carboxamide1058428-45-7C₂₅H₃₂N₂O₂

4-(((1-((3r,5r,7r)-Adamantane-1-carbonyl)piperidin-4-yl)methoxy)methyl)benzonitrile chemical structure, C25H32N2O2, CAS 1396685-36-1

4-(((1-((3r,5r,7r)-Adamantane-1-carbonyl)piperidin-4-yl)methoxy)methyl)benzonitrile1396685-36-1C₂₅H₃₂N₂O₂

2-(4-Methylphenoxy)-1-[4-(4-phenylcyclohexyl)piperazin-1-yl]ethanone chemical structure, C25H32N2O2, CAS 423744-38-1

2-(4-Methylphenoxy)-1-[4-(4-phenylcyclohexyl)piperazin-1-yl]ethanone423744-38-1C₂₅H₃₂N₂O₂

2,4-Imidazolidinedione, 5-nonyl-5-phenyl-3-(phenylmethyl)- chemical structure, C25H32N2O2, CAS 824392-48-5

2,4-Imidazolidinedione, 5-nonyl-5-phenyl-3-(phenylmethyl)-824392-48-5C₂₅H₃₂N₂O₂

2-(Morpholin-4-yl)-1-(2,2,4,6-tetramethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethanone chemical structure, C25H32N2O2, CAS 337493-96-6

2-(Morpholin-4-yl)-1-(2,2,4,6-tetramethyl-4-phenyl-3,4-dihydroquinolin-1(2H)-yl)ethanone337493-96-6C₂₅H₃₂N₂O₂

9-[4-(Dimethylamino)phenyl]-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione chemical structure, C25H32N2O2, CAS 3476-94-6

9-[4-(Dimethylamino)phenyl]-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione3476-94-6C₂₅H₃₂N₂O₂

Frequently asked questions

Quick answers about Dextromoramide, based on the data on this page

What is Dextromoramide?

Dextromoramide is an N-acylpyrrolidine arising by formal condensation of pyrrolidine with (3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenylbutanoic acid. An opioid analgesic that is structurally related to methadone, it is more poweful than morphine but shorter acting.

What is the CAS number of Dextromoramide?

The CAS registry number of Dextromoramide is 357-56-2. Other or deprecated CAS numbers: 13013-15-5.

What is the molecular formula and weight of Dextromoramide?

The molecular formula of Dextromoramide is C25H32N2O2 and its molar mass is 392.54 g/mol.

What is Dextromoramide used for?

Use classes: Pharmaceuticals.

Is Dextromoramide hazardous?

No GHS hazard classification for Dextromoramide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Dextromoramide?

Dextromoramide is usually classified under HS code 293491 (Aminorex (INN), brotizolam (INN), clotiazepam (INN), cloxazolam (INN), dextromoramide…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Dextromoramide on CompoundList?

No. Dextromoramide is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Dextromoramide

Key facts

What is Dextromoramide?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Dextromoramide suppliers

Dextromoramide price

Uses and applications

Industries and functions

Pharmacological actions

Roles

Functional uses

Regulatory status

Controls

HS code and trade data

Global trade

Related chemicals

Salt and hydrate forms

Stereoisomers and isotopic forms

Same formula isomers

Frequently asked questions

What is Dextromoramide?

What is the CAS number of Dextromoramide?

What is the molecular formula and weight of Dextromoramide?

What is Dextromoramide used for?

Is Dextromoramide hazardous?

What is the HS code of Dextromoramide?

Can I buy Dextromoramide on CompoundList?

Guides for buyers