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Insecticides and acaricides

Diflubenzuron

Also known as Difluron, Dimilin, Larvakil

CAS 35367-38-5Formula C14H9ClF2N2O2Molar mass 310.69 g/molEC 252-529-3
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 156 suppliers listed
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Diflubenzuron chemical structure, C14H9ClF2N2O2, CAS 35367-38-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless crystals
Melting point
228 °C
Boiling point
257 °C
Density
1.57 at 20 °C
Solubility
In water, 0.08 mg/L at 25 °C. pH 7
HS code
292519
Category
Insecticides and acaricides
UN number
UN 3077
Illustrative photo, colourless crystals in an open fibre drum in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Diflubenzuron?

Plain description, key identifiers and synonyms

Diflubenzuron is a benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group. It has a role as an insect sterilant. It is a benzoylurea insecticide and a member of monochlorobenzenes. It is functionally related to a 1,3-difluorobenzene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide
CAS number
35367-38-5 CAS number cross-checkedOther or deprecated CAS: 1581694-97-4
EC numbers
252-529-3, 808-703-1
Molecular formula
C14H9ClF2N2O2
UNII
J76U6ZSI8D
MDL number
MFCD00055343
InChIKey
QQQYTWIFVNKMRW-UHFFFAOYSA-N
InChI
InChI=1S/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)
SMILES (canonical and isomeric)
C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC=C(C=C2)Cl)F

Synonyms

  • Difluron
  • Dimilin
  • Larvakil
  • Duphacid
  • Astonex
  • Dimilin G1
  • Dimilin G4
  • 1-(4-Chlorophenyl)-3-(2,6-difluorobenzoyl)urea
  • Dimilin ODC-45
  • Dimilin WP-25
  • Thompson Hayward 6040
  • Dioflubenzuron
  • Thompson-hayward TH6040
  • Philips-duphar PH 60-40
  • OMS 1804
  • TH 6040
  • 1-(p-Chlorophenyl)-3-(2,6-difluorobenzoyl)urea
  • DU 112307
  • N-(4-Chlorophenylcarbamoyl)-2,6-difluorobenzamide
  • ENT 29054
  • PDD 6040I
  • N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide
  • N-(((4-Chlorophenyl)amino)carbonyl)-2,6-difluorobenzamide
  • Benzamide, N-(((4-chlorophenyl)amino)carbonyl)-2,6-difluoro-
  • N-((4-Chlorophenyl)carbamoyl)-2,6-difluorobenzamide
Show all 37 synonyms
  • n-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide
  • Benzamide, N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluoro-
  • 3-(4-chlorophenyl)-1-((2,6-difluorophenyl)carbonyl)urea
  • 3-(4-chlorophenyl)-1-[(2,6-difluorophenyl)carbonyl]urea
  • N-{[(4-chlorophenyl)amino]carbonyl}-2,6-difluorobenzamide
  • Micromite
  • Thompson-Hayward 6040
  • PH 60-40
  • N-[[(4-Chlorophenyl)amno]carbonyl]-2,6-difluorobenzamide
  • C14H9ClF2N2O2
  • Diflubenzuron, N-[[(4-Chlorophenyl)amino]carbonyl]-2,6-di-fluorobenzamide, 1-(4-Chlorophenyl)-3-(2,6-difluorobenzoyl)urea, Difluron, Dimilin
  • Iflubenzuron

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless crystalsexp.
Melting point
228 °Cexp.
Boiling point
257 °Cexp.
Density
1.57 at 20 °Cexp.
Solubility
In water, 0.08 mg/L at 25 °C. pH 7exp.
Vapour pressure
9 × 10⁻¹⁰ mm Hg at 25 °C /gas saturation method/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
310.69 g/molcalc.
Exact mass
310.0321 Dacalc.
LogP (octanol/water)
3.58calc.
Topological polar surface area
58.2 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NC(=O)c1ccccc1)Nc1ccccc1

O=C(NC(=O)c1ccccc1)Nc1ccccc1

2 rings, 18 atoms, the 1-Benzoyl-3-phenylurea ring system.

212 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H312Harmful in contact with skin.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (10)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3077

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Diflubenzuron suppliers

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All 156 suppliers
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Where suppliers are based

156 suppliers in 20 countries

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Diflubenzuron price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Acaricide/Insecticide (insect growth regulator).

Restricted Use Pesticide for sale and use by certified pesticide applicators or person under their supervision due to toxicity to aquatic invertebrates.

For control of a wide range of leaf-eating insects in forestry, woody ornamentals and fruit. Controls certain major pests in cotton, soya beans, citrus, tea, vegetables and mushrooms. Also controls larvae of flies, mosquitoes, grasshoppers and migratory locusts. Used as an ectoparasiticide on sheep for control of lice, fleas and blowfly larvae. Due to its selectivity and rapid degradation in soil and water, diflubenzuron has no or only a slight effect on the natural enemies of various harmful insect species. These properties make it suitable for inclusion in integrated control programmes.

Diflubenzuron ... is an experimental larvicide incorporated in feed of cattle for control of face (Musca autumnalis DeGeer) or house flies (Musca domestica L.) at their immature larval stage in manure.

Use classes: Insecticides, Pesticides.

Roles

  • chemosterilant
  • insect sterilant
  • insecticide
  • pesticide

Functional uses

  • Biocide

How it is made

2,6-Difluorobenzamide is reacted with 4-chlorophenyl isocyanate in an organic solvent medium. The product isolated from the reaction mixture has a mp of 210-230 °C.

Preparation: K. Wellinga, R. Mulder, German patent 2123236, eidem, United States of America patent 3748356 (1971, 1973 both to Philips).

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Diflubenzuron is traded under.

HS 2925.19Indicative HS code

Imides and their derivatives, salts thereof, other

World exports in 2024
$295M
+11.7% vs 2023, imports $348M
2019 to 2024
Top exporters
  1. China29.7%
  2. Japan22.7%
  3. United Kingdom10.0%
Top importers
  1. United States12.7%
  2. Brazil12.6%
  3. China10.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Diflubenzuron is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Diflubenzuron, based on the data on this page

What is Diflubenzuron?

Diflubenzuron is a benzoylurea insecticide that is urea in which a hydrogen attached to one of the nitrogens is replaced by a 4-chlorophenyl group, and a hydrogen attached to the other nitrogen is replaced bgy a 2,6-difluorobenzoyl group. It has a role as an insect sterilant.

What is the CAS number of Diflubenzuron?

The CAS registry number of Diflubenzuron is 35367-38-5. Other or deprecated CAS numbers: 1581694-97-4.

What is the molecular formula and weight of Diflubenzuron?

The molecular formula of Diflubenzuron is C14H9ClF2N2O2 and its molar mass is 310.69 g/mol.

What is Diflubenzuron used for?

Acaricide/Insecticide (insect growth regulator). Restricted Use Pesticide for sale and use by certified pesticide applicators or person under their supervision due to toxicity to aquatic invertebrates. For control of a wide range of leaf-eating insects in forestry, woody ornamentals and fruit.

Is Diflubenzuron hazardous?

Diflubenzuron carries the GHS signal word "Warning". Main hazards: harmful in contact with skin, may cause damage to organs through prolonged or repeated exposure, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Diflubenzuron?

Diflubenzuron is usually classified under HS code 292519 (Imides and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Diflubenzuron?

CompoundList lists 156 suppliers of Diflubenzuron in China, Brazil, United States, India and 16 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Diflubenzuron in India?

10 suppliers in India list Diflubenzuron on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Diflubenzuron?

Suppliers quote Diflubenzuron on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Diflubenzuron

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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