CompoundList
Sign in
Respiratory, allergy and digestive drugs

Donormil

Also known as Doxylamine succinate, Decapryn, Gittalun

CAS 562-10-7Formula C21H28N2O5Molar mass 388.46 g/molEC 209-228-7
GHS signal word: Warning. Pictograms: Harmful or irritant 66 suppliers listed Drug substance
Get quotes Compare 66 suppliers
Donormil chemical structure, C21H28N2O5, CAS 562-10-7
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Powder
Melting point
102.8 to 107.8
Solubility
Greater than or equal to 100 mg/mL at 72 °F
HS code
293339
Category
Respiratory, allergy and digestive drugs
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Donormil?

Plain description, key identifiers and synonyms

Doxylamine succinate is an organic molecular entity.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
butanedioic acid, N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine
CAS number
562-10-7 CAS number cross-checked
EC number
209-228-7
Molecular formula
C21H28N2O5
UNII
V9BI9B5YI2
MDL number
MFCD00056168
InChIKey
KBAUFVUYFNWQFM-UHFFFAOYSA-N
InChI
InChI=1S/C17H22N2O.C4H6O4/c1-17(20-14-13-19(2)3,15-9-5-4-6-10-15)16-11-7-8-12-18-16;5-3(6)1-2-4(7)8/h4-12H,13-14H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
SMILES (canonical and isomeric)
CC(C1=CC=CC=C1)(C2=CC=CC=N2)OCCN(C)C.C(CC(=O)O)C(=O)O

Synonyms

  • Doxylamine succinate
  • Decapryn
  • Gittalun
  • Unisom
  • Hoggar N
  • Doxy-sleep-aid
  • A-H Injection
  • Mereprine
  • Sedaplus
  • Doxylamine succinate (1:1)
  • Alsodorm
  • Donormyl
  • Dormidina
  • Meraprina
  • Decapryn succinate (1:1)
  • Topcare sleep aid
  • Dimethylaminoethoxy-methyl-benzyl-pyridine succinate
  • Doxylamine succinate (USP)
  • 2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate
  • 2-(alpha-(2-Dimethylaminoethoxy)-alpha-methylbenzyl)pyridine succinate
  • Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-, butanedioate (1:1)
  • Bonjesta component doxylamine succinate
  • Diclegis component doxylamine succinate
  • Bendectin component doxylamine succinate
  • Diclectin component doxylamine succinate
Show all 38 synonyms
  • Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, succinate (1:1)
  • Sambrosa
  • Sambrosa Night
  • sleep aid ultra
  • ultra sleep aid
  • Sleep-aid
  • Unisom Sleeptabs
  • Sleep Aid
  • Nocto Sleep Aid
  • Nighttime Sleep-aid
  • Nighttime Sleep Aid
  • Vicks ZzzQuil Ultra
  • Dg Health Sleep Aid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Powderexp.
Melting point
102.8 to 107.8exp.
Solubility
Greater than or equal to 100 mg/mL at 72 °Fexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
388.46 g/molcalc.
Exact mass
388.1998 Dacalc.
LogP (octanol/water)
2.86calc.
Topological polar surface area
99.96 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
9calc.
Heavy atoms
28calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.38calc.
Formal charge
0calc.
Stereocentres
1calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cc2ccccn2)cc1

c1ccc(Cc2ccccn2)cc1

2 rings, 13 atoms, the 2-(Phenylmethyl)pyridine ring system.

671 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
Precautionary statements (13)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Donormil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 66 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

66 suppliers in 12 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Donormil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Histamine H1 Antagonists

Roles

  • antiinfective agent
  • pharmaceutical

Functional uses

  • Pharmaceutical

Pharmacology

Doxylamine Succinate is a pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate competitively blocks the histamine H1 receptor and limits the typical allergic and anaphylactic responses, including bronchoconstriction, vasodilation, increased capillary permeability, and spasmodic contraction of gastrointestinal smooth muscle, caused by actions of histamine on bronchial and gastrointestinal smooth muscles, and on capillaries. This drug also prevents histamine-induced pain and itching of the skin and mucous membranes.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Donormil is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Donormil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Donormil, based on the data on this page

What is Donormil?

Doxylamine succinate is an organic molecular entity.

What is the CAS number of Donormil?

The CAS registry number of Donormil is 562-10-7.

What is the molecular formula and weight of Donormil?

The molecular formula of Donormil is C21H28N2O5 and its molar mass is 388.46 g/mol.

What is Donormil used for?

Use classes: Animal Drugs.

Is Donormil hazardous?

Donormil carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful in contact with skin, harmful if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Donormil?

Donormil is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Donormil?

CompoundList lists 66 suppliers of Donormil in India, China, United States, Germany and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Donormil in India?

24 suppliers in India list Donormil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Donormil?

Suppliers quote Donormil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Donormil

Get quotes for Donormil

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Donormil
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Donormil with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/donormil-562-10-7" title="Donormil structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Respiratory, allergy and digestive drugs or HS code 293339

66 suppliers
Free quotes, contact stays private
Get quotes