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Cardiovascular and metabolic drugs

Dronedarone

Also known as Dronedarona, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide, N-(2-Butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide

CAS 141626-36-0Formula C31H44N2O5SMolar mass 556.77 g/molEC 604-240-2
GHS signal word: Danger. Pictograms: Serious health hazard, Hazardous to the environment 82 suppliers listed Drug substance
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Dronedarone chemical structure, C31H44N2O5S, CAS 141626-36-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
141626-36-0
Formula
C31H44N2O5S
Appearance
Crystals from acetone/hexane
Melting point
149 to 153
HS code
293590
Category
Cardiovascular and metabolic drugs
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Dronedarone?

Plain description, key identifiers and synonyms

Dronedarone is a member of the class of 1-benzofurans used for the treatment of cardiac arrhythmias. It has a role as a xenobiotic, an anti-arrhythmia drug and an environmental contaminant. It is a sulfonamide, an aromatic ether, a member of 1-benzofurans, a tertiary amino compound and an aromatic ketone.

Dronedarone is a drug used mainly for the indication of cardiac arrhythmias.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide
CAS number
141626-36-0 CAS number cross-checked
EC number
604-240-2
Molecular formula
C31H44N2O5S
UNII
JQZ1L091Y2
MDL number
MFCD00910331
InChIKey
ZQTNQVWKHCQYLQ-UHFFFAOYSA-N
InChI
InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3
SMILES (canonical and isomeric)
CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC

Synonyms

  • Dronedarona
  • N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide
  • N-(2-Butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide
  • Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-
  • N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide
  • Methanesulfonamide, N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-
  • N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide
  • N-[2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl]methanesulfonamide
  • dronedaronum
  • N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-1-benzofuran-5-yl)methanesulfonamide
  • Multaq
  • Dronedarone base
  • Dronedarone (INN)
  • N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)benzofuran-5-yl)methanesulfonamide
  • n-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide
  • N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]benzofuran-5-yl]methanesulfonamide
  • Dronedarone (Standard)
  • n-[2-butyl-3-({4-[3-(dibutylamino)propoxy]p
  • N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)benzofuran-5-yl) methanesulfonamide
  • N-[2-butyl-3-(p-{3-(dibutylamino)propoxy} benzoyl)-5-benzofuranyl]methanesulfonamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from acetone/hexaneexp.
Melting point
149 to 153exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
556.77 g/molcalc.
Exact mass
556.2971 Dacalc.
LogP (octanol/water)
7.05calc.
Topological polar surface area
88.85 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
18calc.
Heavy atoms
39calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.52calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(c1ccccc1)c1coc2ccccc12

O=C(c1ccccc1)c1coc2ccccc12

3 rings, 17 atoms.

225 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H360May damage fertility or the unborn child.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dronedarone suppliers

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All 82 suppliers
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Where suppliers are based

82 suppliers in 14 countries

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Dronedarone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Arrhythmia Agents

Roles

  • anti-arrhythmia drug
  • cardiovascular drug
  • environmental contaminant
  • pharmaceutical
  • xenobiotic

Pharmacology

Dronedarone is an Antiarrhythmic.

How it is made

Preparation: J. Gubin et al., EP 471609, eidem, US 5223510 (1992, 1993 both to Sanofi)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dronedarone is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Dronedarone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dronedarone, based on the data on this page

What is Dronedarone?

Dronedarone is a member of the class of 1-benzofurans used for the treatment of cardiac arrhythmias. It has a role as a xenobiotic, an anti-arrhythmia drug and an environmental contaminant. It is a sulfonamide, an aromatic ether, a member of 1-benzofurans, a tertiary amino compound and an aromatic ketone.

What is the CAS number of Dronedarone?

The CAS registry number of Dronedarone is 141626-36-0.

What is the molecular formula and weight of Dronedarone?

The molecular formula of Dronedarone is C31H44N2O5S and its molar mass is 556.77 g/mol.

What is Dronedarone used for?

Known uses and roles of Dronedarone include cardiovascular drugs in pharmaceuticals, anti-arrhythmia drug, cardiovascular drug, environmental contaminant, pharmaceutical and 2 more.

Is Dronedarone hazardous?

Dronedarone carries the GHS signal word "Danger". Main hazards: may damage fertility or the unborn child, may cause damage to organs through prolonged or repeated exposure, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dronedarone?

Dronedarone is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Dronedarone?

CompoundList lists 82 suppliers of Dronedarone in United States, China, India, Spain and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Dronedarone in India?

5 suppliers in India list Dronedarone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Dronedarone?

Suppliers quote Dronedarone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Dronedarone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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