Murcko scaffold
Ring system with 3 rings and 17 atoms
226 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 226
- With full pages
- 55
Scaffold SMILES
O=C(c1ccccc1)c1coc2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 226 chemicals
![[2-[4-[(2-Butylbenzofuran-3-yl)carbonyl]-2,6-diiodophenoxy]ethyl]diethylaminium chemical structure, C25H30I2NO3+, CAS 135048-43-0](/s/IYIKLHRQXLHMJQ-UHFFFAOYSA-O.svg)
[2-[4-[(2-Butylbenzofuran-3-yl)carbonyl]-2,6-diiodophenoxy]ethyl]diethylaminium
CAS 135048-43-0C25H30I2NO3+
Amiodarone
CAS 1951-25-3C25H29I2NO3
Benzbromarone
CAS 3562-84-3C17H12Br2O3
Benziodarone
CAS 68-90-6C17H12I2O3
Etabenzarone
CAS 15686-63-2C23H27NO3
![{4-[(Dimethylamino)methyl]-5-hydroxy-1-benzofuran-3-yl}(phenyl)methanone chemical structure, C18H17NO3, CAS 19303-58-3](/s/AYBQHIDQEUQFOJ-UHFFFAOYSA-N.svg)
{4-[(Dimethylamino)methyl]-5-hydroxy-1-benzofuran-3-yl}(phenyl)methanone
CAS 19303-58-3C18H17NO3
(2-Butylbenzofuran-3-yl) (4-hydroxy-3,5-diiodophenyl) ketone
CAS 1951-26-4C19H16I2O3
Methanone, (2-ethyl-3-benzofuranyl)(4-methoxyphenyl)-
CAS 3343-80-4C18H16O3
(2-Butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone
CAS 52490-15-0C19H18O3
Desethylamiodarone
CAS 83409-32-9C23H25I2NO3
Di-N-desethylamiodarone
CAS 94317-95-0C21H21I2NO3
Bromobenzarone
CAS 94729-09-6C17H13BrO3
1'-Hydroxybenzbromarone
CAS 125729-46-6C17H12Br2O4
Methanone, (2-butyl-3-benzofuranyl)(4-(3-(dimethylamino)propoxy)-3,5-diiodophenyl)-
CAS 77828-26-3C24H27I2NO3
Dronedarone
CAS 141626-36-0C31H44N2O5S
Ati 2042
CAS 270587-33-2C27H31I2NO5
2,2-Dimethylpropyl 3-(4-(2-(diethylamino)ethoxy)-3,5-diiodobenzoyl)2-benzofuranacetate
CAS 345267-16-5C28H33I2NO5
Ethyl 3-(4-(2-(diethylamino)ethoxy)-3,5-diiodobenzoyl)-2-benzofuranacetate
CAS 270587-30-9C25H27I2NO5
Benzarone
CAS 1477-19-6C17H14O3
(4-Hydroxyphenyl)(2-isopropyl-1-benzofuran-3-yl)methanone
CAS 10454-62-3C18H16O3
![(4-Hydroxy-3,5-diiodophenyl)[2-(propan-2-yl)-1-benzofuran-3-yl]methanone chemical structure, C18H14I2O3, CAS 94330-71-9](/s/ZRBISRXULNIITH-UHFFFAOYSA-N.svg)
(4-Hydroxy-3,5-diiodophenyl)[2-(propan-2-yl)-1-benzofuran-3-yl]methanone
CAS 94330-71-9C18H14I2O3
3-(3,5-Dibromo-4-hydroxy-benzoyl)-2-ethyl-benzofuran-6-sulfonic acid dimethylamide
CAS 765317-71-3C19H17Br2NO5S
(2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3-iodophenyl)methanone
CAS 85642-08-6C25H30INO3
Deiodoamiodarone
CAS 23551-25-9C25H31NO3
- 1 suppliers(5-Hydroxy-1-benzofuran-3-yl)(phenyl)methanone17249-62-6C15H10O3
- (5-Methoxy-3-benzofuranyl)phenylmethanone19303-49-2C16H12O3
- (2,5-Dimethoxyphenyl)(5-hydroxy-1-benzofuran-3-yl)methanone169944-36-9C17H14O5
- (2,5-Dimethoxyphenyl)-(5-methoxy-1-benzofuran-3-yl)methanone310458-23-2C18H16O5
- Methanone, (4-chloro-5-hydroxy-3-benzofuranyl)phenyl-88673-85-2C15H9ClO3
- 3-(3-Benzoyl-6-chloro-4,5-dihydroxy-1-benzofuran-7-yl)pentane-2,4-dione352553-38-9C20H15ClO6
- 3-(4-Chlorobenzoyl)benzofuran-5-yl acetate329210-02-8C17H11ClO4
- 1 suppliers(5-Hydroxy-1-benzofuran-3-yl)(4-methoxyphenyl)methanone5219-82-9C16H12O4
- (2,5-Dihydroxyphenyl)(5-hydroxy-3-benzofuranyl)methanone312513-29-4C15H10O5
- Ketone, 3-benzoylbenzofuran-5-yl hydroperoxymethyl82039-81-4C17H12O5
- Benzofuran, 5-(hydroperoxyacetyl)-3-(p-toluoyl)-82039-82-5C18H14O5
- (5-Methoxy-2-methyl-1-benzofuran-3-yl)-(4-methoxyphenyl)methanone107683-59-0C18H16O4
- (5-Hydroxy-1-benzofuran-3-yl)-(4-methylphenyl)methanone17249-63-7C16H12O3
- Methanone, (4-chloro-5-hydroxy-3-benzofuranyl)(4-methylphenyl)-88673-86-3C16H11ClO3
- (4-Bromophenyl)-(5-methoxy-2-methyl-1-benzofuran-3-yl)methanone177915-49-0C17H13BrO3
- 3-(2,5-Dimethoxybenzoyl)-1-benzofuran-5-yl acetate352553-06-1C19H16O6
- 3-(4-Methoxybenzoyl)-1-benzofuran-5-yl acetate344875-56-5C18H14O5
- (4-Chlorophenyl)(5-hydroxy-2-methyl-1-benzofuran-3-yl)methanone177915-46-7C16H11ClO3
- (4-Fluorophenyl)(5-hydroxy-2-methyl-1-benzofuran-3-yl)methanone178261-68-2C16H11FO3
- (5-Hydroxy-2-methyl-1-benzofuran-3-yl)(4-methoxyphenyl)methanone178261-69-3C17H14O4
- (4-Aminophenyl)-(5-methoxy-1-benzofuran-3-yl)methanone352553-08-3C16H13NO3
- (5-Hydroxy-1-benzofuran-3-yl)-(4-nitrophenyl)methanone371943-32-7C15H9NO5
- (4-Bromophenyl)(5-hydroxy-2-methyl-1-benzofuran-3-yl)methanone177915-47-8C16H11BrO3
- 3-Benzoyl-1-benzofuran-5-yl acetate344868-28-6C17H12O4
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cnc3ccccc32)cc1168 chemicals![Scaffold O=c1[nH]c(=O)c2c(ncn2Cc2ccccc2)[nH]1](/scaffold/XDUTVTQACWYOMX-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2Cc2ccccc2)[nH]1167 chemicals
c1ccc(Cn2ccc3ccccc32)cc1100 chemicals
O=S(=O)(c1ccccc1)n1cnc2ccccc2168 chemicals
O=S(=O)(c1ccccc1)n1ccc2ccccc2143 chemicals
O=c1oc2ccccc2n1Cc1ccccc138 chemicals
O=S(=O)(c1ccccc1)N1CCc2ccccc2133 chemicals
O=C(c1ccccc1)N1CCc2ccccc2133 chemicals
O=C(c1ccccc1)n1ccc2ccccc2131 chemicals
c1ccc(Cn2cnc3cncnc32)cc130 chemicals
O=C(c1ccccc1)c1ccc2ccccn1229 chemicals
O=C1C(=O)N(Cc2ccccc2)c2ccccc2128 chemicals