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Endomorphin 2

Also known as Endomorphin-2, tetrapeptide-15, Tyr-Pro-Phe-Phe-NH2

CAS 141801-26-5Formula C32H37N5O5Molar mass 571.68 g/mol
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Endomorphin 2 chemical structure, C32H37N5O5, CAS 141801-26-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
141801-26-5
Formula
C32H37N5O5
Molar mass
571.68 g/mol
HS code
293399
Category
Peptides

What is Endomorphin 2?

Plain description, key identifiers and synonyms

Endomorphin 2 is a chemical substance with the molecular formula C32H37N5O5 and a molar mass of 571.68 g/mol. Its CAS registry number is 141801-26-5. The IUPAC name is (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
CAS number
141801-26-5 CAS number cross-checked
Molecular formula
C32H37N5O5
UNII
3PH5M0466G
MDL number
MFCD01321064
InChIKey
XIJHWXXXIMEHKW-LJWNLINESA-N
InChI
InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1
Canonical SMILES
NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(N)Cc1ccc(O)cc1
Isomeric SMILES
C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N

Synonyms

  • Endomorphin-2
  • tetrapeptide-15
  • Tyr-Pro-Phe-Phe-NH2
  • L-Phenylalaninamide, L-tyrosyl-L-prolyl-L-phenylalanyl-
  • tyrosyl-prolyl-phenylalanyl-phenylalaninamide
  • l-tyrosyl-l-prolyl-l-phenylalanyl-l-phenylalaninamide
  • (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
  • l-tyrosyl-l-prolyl-l-phenylalanyl-l-phenylalaninamide, (-)-
  • (2S)-2-{[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-carbamoyl-2-phenylethyl]-3-phenylpropanamide
  • (2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N-((2S)-1-(((2S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
  • (2S)-2-(((2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)formamido)-N-((1S)-1-carbamoyl-2-phenylethyl)-3-phenylpropanamide
  • H-Tyr-Pro-Phe-Phe-NH2
  • (S)-1-(L-tyrosyl)-N-((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide
  • H-YPFF-NH2
  • Endomorphin-2 trifluoroacetate salt
  • (2S)-N-[(1S)-2-[[(1S)-2-amino-1-benzyl-2-oxo-ethyl]amino]-1-benzyl-2-oxo-ethyl]-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
  • (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide
  • (S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide
  • 1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
571.68 g/molcalc.
Exact mass
571.2795 Dacalc.
LogP (octanol/water)
1.19calc.
Topological polar surface area
167.9 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
12calc.
Heavy atoms
42calc.
Rings
4calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NCCc1ccccc1)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)CCc1ccccc1

O=C(NCCc1ccccc1)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)CCc1ccccc1

4 rings, 37 atoms.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Endomorphin 2 suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

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Where suppliers are based

8 suppliers in 4 countries

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Endomorphin 2 price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Analgesics, Opioid

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Endomorphin 2 is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Endomorphin 2 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Endomorphin 2, based on the data on this page

What is Endomorphin 2?

Endomorphin 2 is a chemical substance with the molecular formula C32H37N5O5 and a molar mass of 571.68 g/mol. Its CAS registry number is 141801-26-5.

What is the CAS number of Endomorphin 2?

The CAS registry number of Endomorphin 2 is 141801-26-5.

What is the molecular formula and weight of Endomorphin 2?

The molecular formula of Endomorphin 2 is C32H37N5O5 and its molar mass is 571.68 g/mol.

What is Endomorphin 2 used for?

Known uses and roles of Endomorphin 2 include analgesics, opioid.

Is Endomorphin 2 hazardous?

No GHS hazard classification for Endomorphin 2 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Endomorphin 2?

Endomorphin 2 is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Endomorphin 2?

CompoundList lists 8 suppliers of Endomorphin 2 in China, United States, United Kingdom and Japan. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Endomorphin 2?

Suppliers quote Endomorphin 2 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Endomorphin 2

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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