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Sweeteners

Erythritol

Also known as meso-Erythritol, Phycitol, Erythrit

CAS 149-32-6Formula C4H10O4Molar mass 122.12 g/molEC 205-737-3
GHS signal word: Warning. Pictograms: Harmful or irritant 182 suppliers listed
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Erythritol chemical structure, C4H10O4, CAS 149-32-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Bipyramidal tetragonal prisms
Melting point
121.5 °C
Boiling point
330.5 °C
Density
1.451 g/cm³ at 20 °C
Solubility
Very soluble in water (saturated solution contains about 61% w/w), soluble in pyridine (…
HS code
290549
Category
Sweeteners
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Erythritol?

Plain description, key identifiers and synonyms

Erythritol is the meso-diastereomer of butane-1,2,3,4-tetrol. It has a role as an antioxidant, a plant metabolite and a human metabolite.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R)-butane-1,2,3,4-tetrol
CAS number
149-32-6 CAS number cross-checkedOther or deprecated CAS: 10030-58-7, 7493-90-5
EC numbers
205-737-3, 626-535-5
Molecular formula
C4H10O4
UNII
RA96B954X6
MDL number
MFCD00004710
InChIKey
UNXHWFMMPAWVPI-ZXZARUISSA-N
InChI
InChI=1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4+
Canonical SMILES
OCC(O)C(O)CO
Isomeric SMILES
C([C@H]([C@H](CO)O)O)O

Synonyms

  • meso-Erythritol
  • Phycitol
  • Erythrit
  • Mesoerythritol
  • Phycite
  • L-Erythritol
  • (2R,3S)-butane-1,2,3,4-tetrol
  • Antierythrite
  • Erythroglucin
  • 1,2,3,4-Butanetetrol, (2R,3S)-rel-
  • Paycite
  • erythro-tetritol
  • Tetrahydroxybutane
  • C*Eridex
  • (2S,3R)-butane-1,2,3,4-tetrol
  • 1,2,3,4-Butanetetrol, (R*,S*)-
  • NIK 242
  • INS NO.968
  • GlyTouCan:G18035IT
  • Erythrite
  • (2R,3S)-rel-Butane-1,2,3,4-tetraol
  • Butanetetrol
  • Erythrol (VAN)
  • i-Erythritol
  • 1,2,3,4-Butanetetrol
Show all 35 synonyms
  • (2r,3s)-butane-1,2,3,4-tetraol
  • Erythritol, meso-
  • rel-(2R,3S)-butane-1,2,3,4-tetraol
  • Erythritol (NF)
  • Butane 1,2,3,4-tetrol (meso-erythritol)
  • Lichen sugar
  • Erythritol (ep monograph)
  • MRY
  • D-Erythritol
  • Cargill Zerose 16957

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Bipyramidal tetragonal prismsexp.
Taste
About twice as sweet as sucroseexp.
Melting point
121.5 °Cexp.
Boiling point
330.5 °Cexp.
Density
1.451 g/cm³ at 20 °Cexp.
Solubility
Very soluble in water (saturated solution contains about 61% w/w), soluble in pyridine (saturated solution contains 2.5% w/w), slightly soluble in alcohol, practically insoluble in etherexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
122.12 g/molcalc.
Exact mass
122.0579 Dacalc.
LogP (octanol/water)
-2.31calc.
Topological polar surface area
80.92 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
8calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Erythritol suppliers

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All 182 suppliers
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Where suppliers are based

182 suppliers in 30 countries

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Erythritol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Erythritol is a naturally occurring noncariogenic excipient used in a variety of pharmaceutical preparations, including in solid dosage forms as a tablet filler, and in coatings. It has also been investigated for use in dry powder inhalers. It is also used in sugar-free lozenges, and medicated chewing gum.

Non-nutritive sweetener in beverages.

Manufacture of erythrityl tetranitrate.

Use classes: Food additives, Cosmetics.

Industries and functions

Pharmacological actions

  • Vasodilator Agents

Roles

  • animal metabolite
  • antioxidant
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • plant metabolite

Functional uses

  • Humectant
  • Softener and conditioner

How it is made

Erythritol is produced on industrial scale by fermentation. ... As starting material, aqueous solutions of glucose or sucrose are used. The naturally occurring yeast Moniliella pollinis, originally isolated from pollen found in a honeycomb, is used for the fermentation. In the fermentation broth, large amounts of erythritol are formed besides other polyols. After filtration, ion exchange chromatography, and concentration, erythritol is crystallized with more than 99% purity.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Food additive

United States

  • TSCA inventory (USA)
    Status: Active in US commerce, Regulatory flags: Added by a premanufacture notice

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Erythritol is traded under.

HS 2905.49Indicative HS code

Acyclic alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives…

World exports in 2024
$474M
−0.8% vs 2023, imports $513M
2019 to 2024
Top exporters
  1. China59.8%
  2. France * partner reported9.8%
  3. Netherlands8.0%
Top importers
  1. United States16.3%
  2. South Korea7.8%
  3. Germany7.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Erythritol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Erythritol, based on the data on this page

What is Erythritol?

Erythritol is the meso-diastereomer of butane-1,2,3,4-tetrol. It has a role as an antioxidant, a plant metabolite and a human metabolite.

What is the CAS number of Erythritol?

The CAS registry number of Erythritol is 149-32-6. Other or deprecated CAS numbers: 10030-58-7, 7493-90-5.

What is the molecular formula and weight of Erythritol?

The molecular formula of Erythritol is C4H10O4 and its molar mass is 122.12 g/mol.

What is Erythritol used for?

Erythritol is a naturally occurring noncariogenic excipient used in a variety of pharmaceutical preparations, including in solid dosage forms as a tablet filler, and in coatings. It has also been investigated for use in dry powder inhalers. It is also used in sugar-free lozenges, and medicated chewing gum.

Is Erythritol hazardous?

Erythritol carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Erythritol?

Erythritol is usually classified under HS code 290549 (Acyclic alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Erythritol?

CompoundList lists 182 suppliers of Erythritol in China, United States, India, Germany and 26 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Erythritol in India?

10 suppliers in India list Erythritol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Erythritol?

Suppliers quote Erythritol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Erythritol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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