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Food antioxidants

Ethoxyquin

Also known as 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline, Santoquin, Ethoxyquine

CAS 91-53-2Formula C14H19NOMolar mass 217.31 g/molEC 202-075-7
GHS signal word: Warning. Pictograms: Harmful or irritant 49 suppliers listed
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Ethoxyquin chemical structure, C14H19NO, CAS 91-53-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Yellow liquid
Melting point
Ca. 0
Boiling point
123 to 125
Density
1.029-1.031 AT 25 °C/25 °C
Flash point
107.2 °C
HS code
293349
Category
Food antioxidants
Illustrative photo, pale yellow liquid in laboratory glassware on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Ethoxyquin?

Plain description, key identifiers and synonyms

Ethoxyquin is a quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6. It has a role as a geroprotector, a herbicide, a genotoxin, a neuroprotective agent, a Hsp90 inhibitor, an UDP-glucuronosyltransferase activator, a food antioxidant and an antifungal agrochemical. It is a member of quinolines and an aromatic ether.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
6-ethoxy-2,2,4-trimethyl-1H-quinoline
CAS number
91-53-2 CAS number cross-checked
EC number
202-075-7
Molecular formula
C14H19NO
UNII
9T1410R4OR
MDL number
MFCD00023883
InChIKey
DECIPOUIJURFOJ-UHFFFAOYSA-N
InChI
InChI=1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3
SMILES (canonical and isomeric)
CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C

Synonyms

  • 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline
  • Santoquin
  • Ethoxyquine
  • Antioxidant EC
  • Stop-Scald
  • Nix-Scald
  • Santoquine
  • Niflex
  • Santoflex A
  • Santoflex AW
  • Dawe's nutrigard
  • Nocrack AW
  • Quinol ED
  • Aries Antox
  • Permanax 103
  • Amea 100
  • Niflex D
  • Antage AW
  • Nocrac AW
  • Ethoxychin
  • Alterungsschutzmittel EC
  • Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-
  • 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline
  • Usaf B-24
  • 1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline
Show all 36 synonyms
  • 1,2-Dihydro-2,2,4-trimethyl-6-ethoxyquinoline
  • 2,2,4-Trimethyl-6-ethoxy-1,2-dihydroquinoline
  • 6-ETMDQ
  • Ethyl 2,2,4-trimethyl-1,2-dihydro-6-quinolinyl ether
  • Santoquine (VAN)
  • 6-ethoxy-2,2,4-trimethyl-1H-quinoline
  • EMQ
  • EQ
  • 6-(ethyloxy)-2,2,4-trimethyl-1,2-dihydroquinoline
  • Santoflex
  • SantoquinEQ

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Yellow liquidexp.
Melting point
Ca. 0exp.
Boiling point
123 to 125exp.
Density
1.029-1.031 AT 25 °C/25 °Cexp.
Flash point
107.2 °Cexp.
Solubility
Less than 1 mg/mL at 68 °Fexp.
Vapour pressure
1.82e-05 mmHg at 32 °F, 0.000256 mmHg at 77 °Fexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
217.31 g/molcalc.
Exact mass
217.1467 Dacalc.
LogP (octanol/water)
3.69calc.
Topological polar surface area
21.26 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.43calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=Cc2ccccc2NC1

C1=Cc2ccccc2NC1

2 rings, 10 atoms, the 1,2-Dihydroquinoline ring system.

336 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ethoxyquin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 49 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

49 suppliers in 14 countries

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Ethoxyquin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Antioxidant in feed & food, antidegradation agent for rubber.

Antioxidant, used as post-harvest fruit-drop to prevent common scald of apples & pears in storge, Formerly added to poultry feeds & forage crops.

Use classes: Pharmaceuticals.

Roles

  • Hsp90 inhibitor
  • UDP-glucuronosyltransferase activator
  • activator
  • additive
  • aetiopathogenetic role
  • agrochemical
  • antifungal agent
  • antifungal agrochemical
  • antimicrobial agent
  • antioxidant
  • enzyme activator
  • enzyme inhibitor
  • food additive
  • food antioxidant
  • food preservative
  • fungicide
  • genotoxin
  • geroprotector
  • herbicide
  • neuroprotective agent
  • pesticide
  • pharmaceutical
  • physiological role
  • protective agent

Functional uses

  • Antioxidant

How it is made

/By passing acetone vapor into p-phenetidine containing 1% of iodine @ 120-130 °c & separating by distillation/

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 613-014-00-2

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ethoxyquin is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…

World exports in 2024
$939M
−14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ethoxyquin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ethoxyquin, based on the data on this page

What is Ethoxyquin?

Ethoxyquin is a quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.

What is the CAS number of Ethoxyquin?

The CAS registry number of Ethoxyquin is 91-53-2.

What is the molecular formula and weight of Ethoxyquin?

The molecular formula of Ethoxyquin is C14H19NO and its molar mass is 217.31 g/mol.

What is Ethoxyquin used for?

Veterinary medication:. Antioxidant in feed & food, antidegradation agent for rubber. Antioxidant, used as post-harvest fruit-drop to prevent common scald of apples & pears in storge, Formerly added to poultry feeds & forage crops. Use classes: Pharmaceuticals.

Is Ethoxyquin hazardous?

Ethoxyquin carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ethoxyquin?

Ethoxyquin is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ethoxyquin?

CompoundList lists 49 suppliers of Ethoxyquin in China, United States, Japan, France and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ethoxyquin in India?

2 suppliers in India list Ethoxyquin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ethoxyquin?

Suppliers quote Ethoxyquin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ethoxyquin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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