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Cardiovascular and metabolic drugs

Etilefrine

Also known as Etilefrin, 3-[2-(Ethylamino)-1-hydroxyethyl]phenol, N-Ethylnorphenylephrine

CAS 709-55-7Formula C10H15NO2Molar mass 181.24 g/molEC 211-910-4
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant 4 suppliers listed
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Etilefrine chemical structure, C10H15NO2, CAS 709-55-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
709-55-7
Formula
C10H15NO2
Molar mass
181.24 g/mol
EC number
211-910-4
HS code
292250
Category
Cardiovascular and metabolic drugs

What is Etilefrine?

Plain description, key identifiers and synonyms

3-[2-(ethylamino)-1-hydroxyethyl]phenol is a member of phenols.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[2-(ethylamino)-1-hydroxyethyl]phenol
CAS number
709-55-7 CAS number cross-checkedOther or deprecated CAS: 10128-36-6
EC numbers
211-910-4, 233-359-9
Molecular formula
C10H15NO2
UNII
ZB6F8MY53V
InChIKey
SQVIAVUSQAWMKL-UHFFFAOYSA-N
InChI
InChI=1S/C10H15NO2/c1-2-11-7-10(13)8-4-3-5-9(12)6-8/h3-6,10-13H,2,7H2,1H3
SMILES (canonical and isomeric)
CCNCC(C1=CC(=CC=C1)O)O

Synonyms

  • Etilefrin
  • 3-[2-(Ethylamino)-1-hydroxyethyl]phenol
  • N-Ethylnorphenylephrine
  • Ethylphenylephrine
  • Ethyladrianol
  • Etilefrina
  • dl-Etilefrin
  • (+-)-Etilefrine
  • Ethylefrine
  • Etilefrinum
  • Corcanfol
  • Ethylnorphenylephrine
  • 1-(3-Hydroxyphenyl)-2-(ethylamino)ethanol
  • alpha-((Ethylamino)methyl)-m-hydroxybenzyl alcohol
  • alpha-(m-Hydroxyphenyl)-beta-(ethylamino)ethanol
  • Benzenemethanol, alpha-((ethylamino)methyl)-3-hydroxy-
  • BENZYL ALCOHOL, alpha-((ETHYLAMINO)METHYL)-m-HYDROXY-
  • 3-(2-(ethylamino)-1-hydroxyethyl)phenol
  • Fetanol
  • Adrianol, Ethyl
  • Eti Puren
  • Etilefrin ratiopharm
  • Hydrochloride, Etilefrine
  • Effortil depot perlongetten
  • Apha-((ethylamino)methyl)-3-hydroxybenzenemethanol
Show all 37 synonyms
  • Etilefrin hydrochloride
  • Etilefrine hcl
  • Effortil
  • Ethyl noradrianol
  • Racemic etilefrine
  • Ethyl adrianol
  • m-Hydroxyphenylethanolethylamine
  • 1-(3'-Hydroxyphenyl)-2-ethylaminoethanol
  • Etiladrianol
  • Etilephrine
  • Etilefrine (INN)
  • Funasol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
181.24 g/molcalc.
Exact mass
181.1103 Dacalc.
LogP (octanol/water)
1.04calc.
Topological polar surface area
52.49 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
13calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301Toxic if swallowed.
  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (22)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Etilefrine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers
  • Ambinter
    France, OrleansUnclaimed profile
    EtilefrineGrade, purity and minimum order on request
    Price on request
    View
  • Clearsynth
    United States, San DiegoUnclaimed profile
    EtilefrineGrade, purity and minimum order on request
    Price on request
    View
  • MP Biomedicals
    United States, SolonUnclaimed profile
    EtilefrineGrade, purity and minimum order on request
    Price on request
    View
  • Vitas-M Laboratory
    Hong Kong, CentralUnclaimed profile
    EtilefrineGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 3 countries

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Etilefrine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Adrenergic alpha-Agonists
  • Adrenergic beta-1 Receptor Agonists
  • Cardiotonic Agents
  • Sympathomimetics
  • Vasoconstrictor Agents

Functional uses

  • Pharmaceutical

Pharmacology

Etilefrine is an adrenergic agonist with vasoconstrictive activity. Etilefrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to a decrease in venous pooling and increase in blood pressure. This agent may also stimulate beta-1 adrenergic receptors, leading to positive chronotropic and inotropic effects.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Etilefrine is traded under.

HS 2922.50Indicative HS code

Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function

World exports in 2024
$3.29B
−5.9% vs 2023, imports $3.19B
2019 to 2024
Top exporters
  1. China39.2%
  2. United Kingdom27.1%
  3. India * partner reported4.8%
Top importers
  1. United States20.7%
  2. Germany7.6%
  3. Italy6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Etilefrine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Etilefrine, based on the data on this page

What is Etilefrine?

3-[2-(ethylamino)-1-hydroxyethyl]phenol is a member of phenols.

What is the CAS number of Etilefrine?

The CAS registry number of Etilefrine is 709-55-7. Other or deprecated CAS numbers: 10128-36-6.

What is the molecular formula and weight of Etilefrine?

The molecular formula of Etilefrine is C10H15NO2 and its molar mass is 181.24 g/mol.

What is Etilefrine used for?

Use classes: Pharmaceuticals.

Is Etilefrine hazardous?

Etilefrine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, harmful if swallowed, harmful in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Etilefrine?

Etilefrine is usually classified under HS code 292250 (Amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Etilefrine?

CompoundList lists 4 suppliers of Etilefrine in United States, France and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Etilefrine?

Suppliers quote Etilefrine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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