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Insecticides and acaricides

Fonofos

Also known as Dyfonate, Dyphonate, Difonate

CAS 944-22-9Formula C10H15OPS2Molar mass 246.34 g/molEC 213-408-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Hazardous to the environment 2 suppliers listed
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Fonofos chemical structure, C10H15OPS2, CAS 944-22-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Light yellow liquid
Melting point
30 °C
Boiling point
380 °C
Density
Relative density (water = 1): 1.16
Flash point
93 °C
HS code
293149
Category
Insecticides and acaricides
UN number
UN 3018
Illustrative photo, pale yellow liquid in sealed glass ampoules on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Fonofos?

Plain description, key identifiers and synonyms

Fonofos is an organothiophosphate insecticide and an organic thiophosphate. It has a role as an agrochemical, an EC 3.1.1.8 (cholinesterase) inhibitor and an EC 3.1.1.7 (acetylcholinesterase) inhibitor.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
ethoxy-ethyl-phenylsulfanyl-sulfanylidene-λ5-phosphane
CAS number
944-22-9 CAS number cross-checkedOther or deprecated CAS: 994-22-9
EC number
213-408-0
Molecular formula
C10H15OPS2
UNII
P4VT8081QO
InChIKey
KVGLBTYUCJYMND-UHFFFAOYSA-N
InChI
InChI=1S/C10H15OPS2/c1-3-11-12(13,4-2)14-10-8-6-5-7-9-10/h5-9H,3-4H2,1-2H3
SMILES (canonical and isomeric)
CCOP(=S)(CC)SC1=CC=CC=C1

Synonyms

  • Dyfonate
  • Dyphonate
  • Difonate
  • Difonatul
  • Fonophos
  • Stauffer N 2790
  • Doubledown
  • Stauffer N2790
  • (+-)-Fonofos
  • Dyfonate Tillam 1-4E
  • O-Ethyl S-phenyl ethylphosphonodithioate
  • OMS 410
  • Dyfonat
  • ENT 25,796
  • O-Ethyl S-phenyl ethyldithiophosphonate
  • Ethylphosphonodithioic acid O-ethyl S-phenyl ester
  • Phosphonodithioic acid, ethyl-, O-ethyl S-phenyl ester
  • (+-)-O-Ethyl S-phenyl ethylphosphonodithioate
  • O-Ethyl S-phenyl ethylphosphonothiolothionate
  • O-Aethyl-S-phenyl-aethyl-dithiophosphonat
  • ethoxy-ethyl-phenylsulfanyl-sulfanylidene-lambda5-phosphane
  • O-Ethyl S-phenyl ethylphosphonrothiolothionate
  • O-Ethyl-S-phenyl ethylphosphonodithioate
  • dyfonate/fonofos
  • Dyfonate 10G
Show all 32 synonyms
  • Fonofos 10 microg/mL in Cyclohexane
  • Fonofos 1000 microg/mL in Methanol
  • Fonofos 100 microg/mL in Acetonitrile
  • (.+/-.)-O-Ethyl S-phenyl ethylphosphonodithioate
  • o-Ethyl S-phenyl p-ethylphosphonodithioate
  • ethoxy-ethyl-phenylsulfanyl-sulfanylidene-?5-phosphane
  • (rs)-(O-Ethyl S-phenyl ethylphosphonodithioate)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Light yellow liquidexp.
Odour
Aromaticexp.
Melting point
30 °Cexp.
Boiling point
380 °Cexp.
Density
Relative density (water = 1): 1.16exp.
Flash point
93 °Cexp.
Solubility
In water, 15.7 mg/l @ 20 °Cexp.
Vapour pressure
45 mPa (3.38 × 10⁻⁴ mm Hg) @ 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
246.34 g/molcalc.
Exact mass
246.0302 Dacalc.
LogP (octanol/water)
4.14calc.
Topological polar surface area
9.23 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
5calc.
Heavy atoms
14calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (14)
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3018
Transport hazard class
6.1
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Fonofos suppliers

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All 2 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 2 countries

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Fonofos price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Classified for restricted use and limited to use by or under the direct supervision of a certified applicator. Formulation: Emulsifiable concentrates 44% and greater, Use Pattern: All uses, Classification: Restricted, Criteria Influencing Restriction: Acute dermal toxicity.

Dyfonate is soil insecticide useful in controlling soil insects such as corn rootworms (diabrotica species), wireworms (elateridae), garden symphylan (scutigerella immaculata), root maggots (hylemya species), crickets (gryllidae) & others.

Control of soil insects (especially mole crickets, corn rootworms, symphylids, wireworms, vine weevil larvae, cockchafer larvae, cabbage root fly, onion fly, carrot fly, wheat bulb fly, etc.) in cereals, maize, sorghum, vegetables, ornamentals, fruit (including citrus and bananas), vines, olives, potatoes, sugar beet, sugar cane, groundnuts, tobacco, and turf.

Use classes: Insecticides, Pharmaceuticals.

Pharmacological actions

  • Cholinesterase Inhibitors
  • Insecticides

Roles

  • agrochemical
  • enzyme inhibitor

Functional uses

  • Biocide

Pharmacology

Fonofos is a synthetic organic thiophosphate compound and organophosphate acetylcholinesterase inhibitor that is used as a pesticide. It is characterized as a colorless or yellow liquid with a mercaptan-like odor and exposure occurs by inhalation, ingestion, or contact.

How it is made

Reaction of thiophenol & o-ethyl ethyl phosphonochloridothioate yields the insecticide fonofos (o-ethyl s-phenyl ethyl phosphonodithioate)

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 015-091-00-2

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fonofos is traded under.

HS 2931.49Indicative HS code

Non-halogenated organo-phosphorous derivatives, other

World exports in 2024
$3.44B
−6.5% vs 2023, imports $3.07B
2022 to 2024
Top exporters
  1. China54.9%
  2. United States25.4%
  3. Germany5.1%
Top importers
  1. United States20.9%
  2. Argentina14.9%
  3. Brazil14.3%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Fonofos is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fonofos, based on the data on this page

What is Fonofos?

Fonofos is an organothiophosphate insecticide and an organic thiophosphate. It has a role as an agrochemical, an EC 3.1.1.8 (cholinesterase) inhibitor and an EC 3.1.1.7 (acetylcholinesterase) inhibitor.

What is the CAS number of Fonofos?

The CAS registry number of Fonofos is 944-22-9. Other or deprecated CAS numbers: 994-22-9.

What is the molecular formula and weight of Fonofos?

The molecular formula of Fonofos is C10H15OPS2 and its molar mass is 246.34 g/mol.

What is Fonofos used for?

Classified for restricted use and limited to use by or under the direct supervision of a certified applicator. Formulation: Emulsifiable concentrates 44% and greater, Use Pattern: All uses, Classification: Restricted, Criteria Influencing Restriction: Acute dermal toxicity.

Is Fonofos hazardous?

Fonofos carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Fonofos?

Fonofos is usually classified under HS code 293149 (Non-halogenated organo-phosphorous derivatives, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Fonofos?

CompoundList lists 2 suppliers of Fonofos in China and Japan. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Fonofos?

Suppliers quote Fonofos on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Fonofos

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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