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Formamide chemical structure, CH3NO, CAS 75-12-7
2D chemical structure

Key facts

What buyers check first

Appearance
Slightly viscous, colorless liquid
Melting point
2.5 °C
Boiling point
210.5 °C
Density
Relative density (water = 1): 1.13
Flash point
154.4 °C
HS code
292419
Category
Analytical reagents
Illustrative photo, 200 litre blue HDPE drums of liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Formamide?

Plain description, key identifiers and synonyms

Formamide is the simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes. It has a role as a solvent. It is a member of formamides, a monocarboxylic acid amide and a one-carbon compound. It is functionally related to a formic acid. It is a tautomer of a formimidic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
formamide
CAS number
75-12-7 CAS number cross-checkedOther or deprecated CAS: 28704-51-0, 60100-09-6
EC number
200-842-0
Molecular formula
CH3NO
UNII
4781T907ZS
MDL number
MFCD00007941
InChIKey
ZHNUHDYFZUAESO-UHFFFAOYSA-N
InChI
InChI=1S/CH3NO/c2-1-3/h1H,(H2,2,3)
SMILES (canonical and isomeric)
C(=O)N

Synonyms

  • Methanamide
  • carbamaldehyde
  • Formimidic acid
  • Formic acid, amide
  • Methanoic acid, amide
  • Amid kyseliny mravenci
  • Methanimidic acid
  • formamid
  • Formic amide
  • Methanamide, Formimidic acid
  • Formamide (deionizde)
  • HCONH2
  • Carbamaldehyde, Methanamide
  • Formamide-13C-15N (9CI)
  • Formamide, ultra pure
  • Amide C1
  • Formamide, puriss. p.a., ACS reagent, >=99.5% (GC/T)
  • Methanamid
  • an amide
  • imidoformic acid
  • Ameisensaeureamid
  • Formamide, Carbamaldehyde, Formimidic acid, Methanamide, NSC 748
  • N-formyl amine
  • amino-formaldehyde
  • primary carboxamide
Show all 34 synonyms
  • Imino-methylalkohol
  • Formamide,Deionized
  • primary carboxamides
  • Formamide, acs
  • Formamide, ACS reagent
  • Monocarboxylic acid amide
  • monocarboxylic acid amides
  • Formamide, >=99.0%
  • Formamide, >=99.5%

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Slightly viscous, colorless liquidexp.
Odour
Faint ammonia odorexp.
Melting point
2.5 °Cexp.
Boiling point
210.5 °Cexp.
Density
Relative density (water = 1): 1.13exp.
Flash point
154.4 °Cexp.
Autoignition temperature
>500exp.
Solubility
In water, 1.0 × 10⁺⁶ mg/l @ 25 °C.exp.
Vapour pressure
6.10 × 10⁻² mm Hg @ 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
45.04 g/molcalc.
Exact mass
45.0215 Dacalc.
LogP (octanol/water)
-0.9calc.
Topological polar surface area
43.09 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
3calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard
120NFPA 704 rating

Hazard statements

  • H360DMay damage the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Formamide suppliers

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All 134 suppliers
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Where suppliers are based

134 suppliers in 19 countries

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Formamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Manufacture of formic esters and hydrocyanic acid by catalytic dehydration.

Intermediate in organic synthesis.

Softener for paper, animal glues, water soluble glues.

Important intermediate in the chemical industry, used for producing heterocyclic compounds, pharmaceuticals, crop protection agents, fungicides, and pesticides, used as a solvent in the manufacture and processing of plastics, to produce formic acid, used to remove coating from copper conductors, used in the spinning of acrylonitrile copolymers, employed in the antistatic finishing of plastics or formation of conductive coatings on plastic particles.

Industrial uses: Intermediate.

Roles

  • solvent

How it is made

Prepared on large scale from carbon monoxide and ammonia at high pressure and temp: Meyer, Orthner, Ber 54, 1705 (1921), 55, 857 (1922), Meyer, German patents 390,798 (1924), 392,409 (1924), 414,257 (1925 to BASF), Weitzel, Herbst, US patent 1,843,434 (1932 to IG Farben).

Interaction of ethyl formate and ammonia with subsequent distillation.

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 616-052-00-8

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Formamide, Ref no: 744, Annex ref: II/744

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Formamide is traded under.

HS 2924.19Indicative HS code

Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$2.38B
−1.7% vs 2023, imports $2.22B
2019 to 2024
Top exporters
  1. China34.7%
  2. Germany12.5%
  3. India * partner reported6.8%
Top importers
  1. United States17.5%
  2. Germany8.8%
  3. India * partner reported6.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Formamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Formamide, based on the data on this page

What is Formamide?

Formamide is the simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes. It has a role as a solvent. It is a member of formamides, a monocarboxylic acid amide and a one-carbon compound. It is functionally related to a formic acid.

What is the CAS number of Formamide?

The CAS registry number of Formamide is 75-12-7. Other or deprecated CAS numbers: 28704-51-0, 60100-09-6.

What is the molecular formula and weight of Formamide?

The molecular formula of Formamide is CH3NO and its molar mass is 45.04 g/mol.

What is Formamide used for?

Manufacture of formic esters and hydrocyanic acid by catalytic dehydration. Intermediate in organic synthesis. Softener for paper, animal glues, water soluble glues.

Is Formamide hazardous?

Formamide carries the GHS signal word "Danger". Main hazards: may damage the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Formamide?

Formamide is usually classified under HS code 292419 (Acyclic amides (including acyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Formamide?

CompoundList lists 134 suppliers of Formamide in China, India, United States, United Kingdom and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Formamide in India?

29 suppliers in India list Formamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Formamide?

Suppliers quote Formamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Formamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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