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Glyphosate

Also known as N-(Phosphonomethyl)glycine, Glyphosphate, N-Phosphomethylglycine

Glyphosate chemical structure, C3H8NO5P, CAS 1071-83-6
2D chemical structure

Key facts

What buyers check first

Appearance
White crystals
Melting point
230 °C
Density
1.7 g/cm³
Solubility
Solubility in water (20 °C): 1050 g/L /Glyphosate trimethylammonium salt/
HS code
293149
Category
Herbicides
UN number
UN 3077
Illustrative photo, colourless crystals beside an amber glass bottle on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Glyphosate?

Plain description, key identifiers and synonyms

Glyphosate is a phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS). It has a role as an EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor, a herbicide and an agrochemical. It is a glycine derivative and a phosphonic acid. It is a conjugate acid of a glyphosate(1-) and a glyphosate(2-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(phosphonomethylamino)acetic acid
CAS number
1071-83-6 CAS number cross-checkedOther or deprecated CAS: 994-61-6
EC number
213-997-4
Molecular formula
C3H8NO5P
UNII
4632WW1X5A
MDL number
MFCD00055350
InChIKey
XDDAORKBJWWYJS-UHFFFAOYSA-N
InChI
InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)
SMILES (canonical and isomeric)
C(C(=O)O)NCP(=O)(O)O

Synonyms

  • N-(Phosphonomethyl)glycine
  • Glyphosphate
  • N-Phosphomethylglycine
  • Glyfos
  • N-Phosphonomethylglycine
  • 2-(phosphonomethylamino)acetic acid
  • Pondmaster
  • Silglif
  • Glycine, N-(phosphonomethyl)-
  • Roundup Max
  • Folusen
  • Glialka
  • Herbatop
  • Phorsat
  • Forsat
  • Hockey
  • Rebel Garden
  • Glyphodin A
  • Glyphosate CT
  • Glialka 36
  • phosphonomethylglycine
  • MON 2139
  • Mon 6000
  • Lancer
  • CP 67573
Show all 38 synonyms
  • Tumbleweed
  • Glifonox
  • Spasor
  • Sonic
  • Sting
  • gliphosate
  • BioTox Pest Detox
  • (carboxymethylazaniumyl)methyl-hydroxyphosphinate
  • N-Phosphonomethyl-glycine
  • GlyGran
  • 2-[(phosphonomethyl)amino]acetic acid
  • 2-((Phosphonomethyl)amino)acetic acid
  • Accord

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White crystalsexp.
Odour
Odorlessexp.
Melting point
230 °Cexp.
Density
1.7 g/cm³exp.
Solubility
Solubility in water (20 °C): 1050 g/L /Glyphosate trimethylammonium salt/exp.
Vapour pressure
9.8 × 10⁻⁸ mm Hg /1.31 × 10⁻² mPa/ at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
169.07 g/molcalc.
Exact mass
169.014 Dacalc.
LogP (octanol/water)
-1.2calc.
Topological polar surface area
106.9 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H318Causes serious eye damage.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (7)
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3077

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Glyphosate suppliers

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All 358 suppliers
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Where suppliers are based

358 suppliers in 32 countries

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Glyphosate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Glyphosate is a non-selective herbicide registered for use on many food and non-food field crops as well as non-crop areas where total vegetation control is desired. When applied at lower rates, glyphosate also is a plant growth regulator.

Control of annual and perennial grasses and broad-leaved weeds, pre-harvest, in cereals, peas, beans, oilseed rape, flax and mustard, at 1.5-2 kg/ha, control of annual and perennial grasses and broad-leaved weeds in stubble and post-planting/pre-emergence of many crops, as a directed spray in vines and olives, at up to 4.3 kg/ha, in orchards, pasture, forestry and industrial weed control, at up to 4.3 kg/ha. As an aquatic herbicide, at 2 kg/ha.

For control of annual and perennial weeds, woody brush, and trees on over 150 crops. Use postdirected in tree and plantation crops, postemergence over Roundup Ready soybeans, and postharvest in fallow periods and noncropland.

Use classes: Herbicides, Pesticides.

Roles

  • agrochemical
  • enzyme inhibitor
  • herbicide
  • pesticide

Functional uses

  • Biocide

Pharmacology

Glyphosate is a synthetic organophosphate compound that blocks the activity of enolpyruvylshikimate-3-phosphate (EPSP) synthase and is used as a broad-spectrum pesticide. It is characterized as a volatile, moderately toxic, colorless, odorless crystalline solid or powder, and exposure occurs by inhalation, ingestion, or contact.

How it is made

Glyphosate is produced by heating a mixture of phosphorous acid and a-amino acetic acid, and then adding formaldehyde.

Preparation: J. E. Franz, German patent 2152826, idem, United States of America patent 3799758 and United States of America patent 3853530 (1972, 1974, 1974 all to Monsanto).

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 607-315-00-8

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Glyphosate is traded under.

HS 2931.49Indicative HS code

Non-halogenated organo-phosphorous derivatives, other

World exports in 2024
$3.44B
−6.5% vs 2023, imports $3.07B
2022 to 2024
Top exporters
  1. China54.9%
  2. United States25.4%
  3. Germany5.1%
Top importers
  1. United States20.9%
  2. Argentina14.9%
  3. Brazil14.3%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Glyphosate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Glyphosate, based on the data on this page

What is Glyphosate?

Glyphosate is a phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).

What is the CAS number of Glyphosate?

The CAS registry number of Glyphosate is 1071-83-6. Other or deprecated CAS numbers: 994-61-6.

What is the molecular formula and weight of Glyphosate?

The molecular formula of Glyphosate is C3H8NO5P and its molar mass is 169.07 g/mol.

What is Glyphosate used for?

Glyphosate is a non-selective herbicide registered for use on many food and non-food field crops as well as non-crop areas where total vegetation control is desired. When applied at lower rates, glyphosate also is a plant growth regulator.

Is Glyphosate hazardous?

Glyphosate carries the GHS signal word "Danger". Main hazards: causes serious eye damage, toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Glyphosate?

Glyphosate is usually classified under HS code 293149 (Non-halogenated organo-phosphorous derivatives, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Glyphosate?

CompoundList lists 358 suppliers of Glyphosate in China, Brazil, United States, India and 28 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Glyphosate in India?

29 suppliers in India list Glyphosate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Glyphosate?

Suppliers quote Glyphosate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Glyphosate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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