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Refrigerants and blowing agents

Halothane

Also known as 2-Bromo-2-chloro-1,1,1-trifluoroethane, Fluothane, Narcotane

CAS 151-67-7Formula C2HBrClF3Molar mass 197.38 g/molEC 205-796-5
GHS signal word: Danger. Pictograms: Corrosive, Harmful or irritant, Serious health hazard 65 suppliers listed
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Halothane chemical structure, C2HBrClF3, CAS 151-67-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless, volatile liquid
Melting point
-118 °C
Boiling point
50.2 °C
Density
Relative density (water = 1): 1.87
Solubility
In water, 4,070 mg/L at 25 °C
HS code
290379
Category
Refrigerants and blowing agents
UN number
UN 3082
Illustrative photo, clear colourless liquid in a glass reagent bottle on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Halothane?

Plain description, key identifiers and synonyms

Halothane is a haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position. It has a role as an inhalation anaesthetic. It is a haloalkane, an organochlorine compound, an organobromine compound and an organofluorine compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-bromo-2-chloro-1,1,1-trifluoroethane
CAS number
151-67-7 CAS number cross-checked
EC number
205-796-5
Molecular formula
C2HBrClF3
UNII
UQT9G45D1P
MDL number
MFCD00009602
InChIKey
BCQZXOMGPXTTIC-UHFFFAOYSA-N
InChI
InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H
SMILES (canonical and isomeric)
C(C(F)(F)F)(Cl)Br

Synonyms

  • 2-Bromo-2-chloro-1,1,1-trifluoroethane
  • Fluothane
  • Narcotane
  • Narcotan
  • Rhodialothan
  • Anestan
  • Ftorotan
  • Fluorotane
  • Ftuorotan
  • Halothan
  • Narkotan
  • Fluktan
  • Halotan
  • Halsan
  • Bromochlorotrifluoroethane
  • Phthorothanum
  • Halotano
  • Chalothane
  • Alotano
  • Freon 123B1
  • Halothanum
  • Fluorothane
  • Bromchlortrifluoraethanum
  • 1-Bromo-1-chloro-2,2,2-trifluoroethane
  • Narcotann ne-spofa
Show all 37 synonyms
  • Ethane, 2-bromo-2-chloro-1,1,1-trifluoro-
  • 1,1,1-Trifluoro-2-bromo-2-chloroethane
  • 1,1,1-Trifluoro-2-chloro-2-bromoethane
  • 2,2,2-Trifluoro-1-chloro-1-bromoethane
  • Ethane, 1-bromo-1-chloro-2,2,2-trifluoro-
  • Rhidialothan
  • (+-)-Halothane
  • 2,2,2-trifluoro-1-bromo-1-chloroethane
  • Fluothane, Halothane, USP
  • 1,1,1-trifluoro-2,2-chlorobromoethane
  • (2RS)-2-Bromo-2-chloro-1,1,1-trifluoroethane
  • Halan

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless, volatile liquidexp.
Odour
Characteristic, sweetish, not unpleasant odorexp.
Melting point
-118 °Cexp.
Boiling point
50.2 °Cexp.
Density
Relative density (water = 1): 1.87exp.
Solubility
In water, 4,070 mg/L at 25 °Cexp.
Vapour pressure
243 mm Hg @ 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
197.38 g/molcalc.
Exact mass
195.8902 Dacalc.
LogP (octanol/water)
2.51calc.
Topological polar surface area
0 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
0calc.
Rotatable bonds
0calc.
Heavy atoms
7calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H318Causes serious eye damage.
  • H335May cause respiratory irritation.
  • H341Suspected of causing genetic defects.
  • H360May damage fertility or the unborn child.
Precautionary statements (18)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3082

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Halothane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 65 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

65 suppliers in 17 countries

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Halothane price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Anesthetic.

Use classes: Animal Drugs.

Pharmacological actions

  • Anesthetics, Inhalation

Roles

  • anaesthetic
  • general anaesthetic
  • inhalation anaesthetic
  • pharmaceutical

Pharmacology

Halothane is a nonflammable, halogenated, hydrocarbon and general inhalation anesthetic. Although the exact mechanism of action is unknown, halothane provides relatively rapid induction of anesthesia by depressing the central nervous system, thereby producing a reversible loss of consciousness and sensation. (NCI05)

How it is made

Bromination of 2-chloro-1,1,2-trifluoroethylene to form 1,2-dibromo-1-chloro-1,2,2-trifluoroethane, isomerization of the product with anhydrous aluminum chloride to 1,1-dibromo-1-chloro-2,2,2-trifluoroethane, and reduction of the latter with hydrogen (catalyzed by platinum), the antimony chloride-catalysed reaction of hydrogen fluoride with 1,2-dibromo-1,1,2-trichloroethane.

Preparation from a mixture of F3CCH2Cl and FCCBrCl: Suckling, Raventos, US 2921098 (1960 to I.C.I.), by rearrangement of F2BrCCHFCl: Scherer, Kuhn, US 2959624 (1960 to Hoechst), from BrClCHCBrCl2: Chapman, McGinty, GB 805764 (1958 to I.C.I.), from Br2ClCCF3: McGinty, US 3082263 (1963 to I.C.I.)

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Halothane is traded under.

HS 2903.79Indicative HS code

Halogenated derivatives of acyclic hydrocarbons containing two or more different halogens not elsewhere…

World exports in 2024
$305M
−6.3% vs 2023, imports $329M
2019 to 2024
Top exporters
  1. China29.6%
  2. India * partner reported23.2%
  3. Netherlands18.4%
Top importers
  1. United States17.5%
  2. Netherlands17.3%
  3. Canada15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Halothane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Halothane, based on the data on this page

What is Halothane?

Halothane is a haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position. It has a role as an inhalation anaesthetic. It is a haloalkane, an organochlorine compound, an organobromine compound and an organofluorine compound.

What is the CAS number of Halothane?

The CAS registry number of Halothane is 151-67-7.

What is the molecular formula and weight of Halothane?

The molecular formula of Halothane is C2HBrClF3 and its molar mass is 197.38 g/mol.

What is Halothane used for?

Veterinary medication:. Anesthetic. Use classes: Animal Drugs.

Is Halothane hazardous?

Halothane carries the GHS signal word "Danger". Main hazards: causes skin irritation, causes serious eye damage, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Halothane?

Halothane is usually classified under HS code 290379 (Halogenated derivatives of acyclic hydrocarbons containing two or more different…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Halothane?

CompoundList lists 65 suppliers of Halothane in United States, China, United Kingdom, Spain and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Halothane in India?

2 suppliers in India list Halothane on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Halothane?

Suppliers quote Halothane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Halothane

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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