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Buffers and biological buffers

Hepps

Also known as 3-(4-(2-Hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid, 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)-, 3-[4-(2-Hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid

CAS 16052-06-5Formula C9H20N2O4SMolar mass 252.34 g/molEC 240-198-8
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Hepps chemical structure, C9H20N2O4S, CAS 16052-06-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
16052-06-5
Formula
C9H20N2O4S
Molar mass
252.34 g/mol
EC number
240-198-8
HS code
293359
Category
Buffers and biological buffers

What is Hepps?

Plain description, key identifiers and synonyms

HEPPS is a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
CAS number
16052-06-5 CAS number cross-checked
EC number
240-198-8
Molecular formula
C9H20N2O4S
UNII
8JN5PQW99C
MDL number
MFCD00006160
InChIKey
OWXMKDGYPWMGEB-UHFFFAOYSA-N
InChI
InChI=1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)
SMILES (canonical and isomeric)
C1CN(CCN1CCCS(=O)(=O)O)CCO

Synonyms

  • 3-(4-(2-Hydroxyethyl)piperazin-1-yl)propane-1-sulfonic acid
  • 1-Piperazinepropanesulfonic acid, 4-(2-hydroxyethyl)-
  • 3-[4-(2-Hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
  • 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonic Acid
  • N-(2-Hydroxyethyl)piperazine-N'-(3-propanesulfonic acid)
  • 4-(2-Hydroxyethyl)piperazine-1-propanesulfonic acid
  • N-2-Hydroxyethylpiperazine-N'-3-propanesulfonic acid
  • N-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid
  • N-2-Hydroxyethylpiperazine-N-3-propanesulfonic acid
  • 4-(2-Hydroxyethyl)piperazine-1-propane-3-sulfonic acid
  • 3-(4-(2-Hydroxyethyl)-1-piperazinyl)propanesulfonic acid
  • EPPS
  • 4-(2-Hydroxyethyl)-1-piperazinepropanesulfonic acid
  • 4-(2-Hydroxyethyl)-1-piperazinepropanesulphonic acid
  • 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid
  • 3-[4-(2-Hydroxyethyl)-1-piperazinyl]propanesulfonicAcid
  • 3-[4-(2-hydroxyethyl)piperazinyl]propanesulfonic acid
  • N-2-Hydroxyethylpiperazine-N'- 3-propanesulfonic acid
  • 4-(2-Hydroxyethyl)-1-piperazinepropane sulfonic acid
  • N-(2-Hydroxyethyl)piperazine-N'-3-propanesulfonic acid
  • 2-Amino-cyclopentanecarboxylic acid
  • EPPS, >=99.5% (titration)
  • EPPS, BioUltra, >=99.0% (T)
  • EPPS, BioXtra, >=99.5% (titration)
  • 3-[4-(2-Hydroxyethyl)-1-piperazinyl]-1-propanesulfonic acid #
Show all 26 synonyms
  • EPPS, BioPerformance Certified, cell culture tested, >=99.5% (titration)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
252.34 g/molcalc.
Exact mass
252.1144 Dacalc.
LogP (octanol/water)
-1.13calc.
Topological polar surface area
81.08 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
6calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CNCCN1

C1CNCCN1

1 ring, 6 atoms, the Piperazine ring system.

6,832 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hepps suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 12 suppliers
12 of 12 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

12 suppliers in 3 countries

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Hepps price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hepps is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hepps is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hepps, based on the data on this page

What is Hepps?

HEPPS is a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine.

What is the CAS number of Hepps?

The CAS registry number of Hepps is 16052-06-5.

What is the molecular formula and weight of Hepps?

The molecular formula of Hepps is C9H20N2O4S and its molar mass is 252.34 g/mol.

What is Hepps used for?

Known uses and roles of Hepps include buffers in research and laboratory.

Is Hepps hazardous?

No GHS hazard classification for Hepps is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hepps?

Hepps is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hepps?

CompoundList lists 12 suppliers of Hepps in China, United States and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Hepps?

Suppliers quote Hepps on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hepps

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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