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Homosalate

Also known as Homomenthyl salicylate, Heliophan, 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate

CAS 118-56-9Formula C16H22O3Molar mass 262.35 g/molEC 204-260-8
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 61 suppliers listed Drug substance
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Homosalate chemical structure, C16H22O3, CAS 118-56-9
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Liquid
Boiling point
161.1 to 165
Density
1.045 at 77 ยฐF - Denser than water, will sink
Flash point
>93.3
Solubility
Insoluble (<1 mg/ml at 79 ยฐF)
HS code
291823
Category
UV filters
Illustrative photo, a closed 1000 litre IBC tote in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Homosalate?

Plain description, key identifiers and synonyms

2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate
CAS number
118-56-9 CAS number cross-checkedOther or deprecated CAS: 52253-93-7
EC number
204-260-8
Molecular formula
C16H22O3
UNII
V06SV4M95S
MDL number
MFCD00019377
INCI name
HOMOSALATE
InChIKey
WSSJONWNBBTCMG-UHFFFAOYSA-N
InChI
InChI=1S/C16H22O3/c1-11-8-12(10-16(2,3)9-11)19-15(18)13-6-4-5-7-14(13)17/h4-7,11-12,17H,8-10H2,1-3H3
SMILES (canonical and isomeric)
CC1CC(CC(C1)(C)C)OC(=O)C2=CC=CC=C2O

Synonyms

  • Homomenthyl salicylate
  • Heliophan
  • 3,3,5-Trimethylcyclohexyl 2-hydroxybenzoate
  • Homosalato
  • (3,3,5-trimethylcyclohexyl) 2-hydroxybenzoate
  • Homosalatum
  • Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester
  • Salicylic Acid 3,3,5-Trimethylcyclohexyl Ester
  • Sunscreen SKINCARE
  • Bulubiu advanced
  • dAlba Vegan Fresh Sun Stick
  • dAlba Vegan Essence Sunscreen
  • Illuminating Daily Moisturizer
  • dAlba Vegan Tone-Up Sunscreen
  • Sun Protection Facial SPF 50
  • Facial Primer Protector SPF 50
  • Bulubiu Face Sunscreen SKINCARE
  • Bulubiu weightless moisturizer
  • Illuminating daily moisturizer spf 30
  • Eight Hour Cream Targeted Sun Defense SPF 50
  • Clean Fresh Sunblock Sunscreen SPF 30 Continuous
  • Homosalate, Ethylhexyl Methoxycinnamate,Titanium Dioxide
  • Homosalate, Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate
  • Homosalate, Octocrylene, Ethylhexyl Methoxycinnamate, Ethylhexyl Salicylate
  • Homosalate, Neo Heliopan, Ethylhexyl Salicylate, Benzophenone-3, Octocrylene, Avovenzona (Butyl Methoxydibenzoylmethane), Titanium Dioxide CI 77891
Show all 37 synonyms
  • 3,3,5-Trimethylcyclohexyl salicylate
  • Coppertone
  • Heliopan
  • Eusolex
  • Filtersol ''A''
  • m-Homomenthyl salicylate
  • 2-Hydroxybenzoic acid 3,3,5-trimethylcyclohexyl ester
  • Salicylic acid, 3,3,5-trimethylcyclohexyl ester
  • Salicylic acid, 3,3,5-trimethylcyclohexyl ester (8CI)
  • Salicylic acid,3,5-trimethylcyclohexyl ester
  • Homosalate (USAN:USP:INN)
  • Filtrosol A

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Liquidexp.
Boiling point
161.1 to 165exp.
Density
1.045 at 77 ยฐF - Denser than water, will sinkexp.
Flash point
>93.3exp.
Solubility
Insoluble (<1 mg/ml at 79 ยฐF)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
262.35 g/molcalc.
Exact mass
262.1569 Dacalc.
LogP (octanol/water)
3.76calc.
Topological polar surface area
46.53 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
2calc.
Heavy atoms
19calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.56calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(OC1CCCCC1)c1ccccc1

O=C(OC1CCCCC1)c1ccccc1

2 rings, 15 atoms, the Cyclohexyl benzoate ring system.

119 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H361dSuspected of damaging the unborn child.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Homosalate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 61 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

61 suppliers in 10 countries

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Homosalate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name HOMOSALATE(fragrance, uv absorber, uv filter)

Pharmacological actions

  • Sunscreening Agents

Functional uses

  • Fragrance
  • Softener and conditioner
  • UV stabilizer

Cosmetic functions

  • Fragrance
  • UV absorber
  • UV filter

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • EU Cosmetics Regulation Annex VI, allowed UV filter
    Name: HOMOSALATE, Ref no: 3, Annex ref: VI/3
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Homosalate is traded under.

HS 2918.23Indicative HS code

Carboxylic acids, (with phenol function but without other oxygen function), other esters of salicylic acidโ€ฆ

World exports in 2024
$260M
โˆ’7.1% vs 2023, imports $277M
2019 to 2024
Top exporters
  1. China41.8%
  2. India * partner reported15.2%
  3. United States6.4%
Top importers
  1. United States19.3%
  2. Brazil8.8%
  3. Singapore7.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Homosalate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Homosalate, based on the data on this page

What is Homosalate?

2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester is a member of phenols and a benzoate ester. It is functionally related to a salicylic acid.

What is the CAS number of Homosalate?

The CAS registry number of Homosalate is 118-56-9. Other or deprecated CAS numbers: 52253-93-7.

What is the molecular formula and weight of Homosalate?

The molecular formula of Homosalate is C16H22O3 and its molar mass is 262.35 g/mol.

What is Homosalate used for?

Use classes: Cosmetics.

Is Homosalate hazardous?

Homosalate carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Homosalate?

Homosalate is usually classified under HS code 291823 (Carboxylic acids with phenol function but without other oxygen function, theirโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Homosalate?

CompoundList lists 61 suppliers of Homosalate in China, United States, India, Malaysia and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Homosalate in India?

14 suppliers in India list Homosalate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Homosalate?

Suppliers quote Homosalate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Homosalate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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