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Emollients

Hypericin

Also known as Hypericum red, hypericine, Cyclosan

CAS 548-04-9Formula C30H16O8Molar mass 504.45 g/molEC 208-941-0
64 suppliers listed
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Hypericin chemical structure, C30H16O8, CAS 548-04-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
548-04-9
Formula
C30H16O8
Molar mass
504.45 g/mol
EC number
208-941-0
HS code
290729
Category
Emollients

What is Hypericin?

Plain description, key identifiers and synonyms

Hypericin is a carbopolycyclic compound. It has a role as an antidepressant. It derives from a hydride of a bisanthene.

Hypericin is an anthraquinone derivative that is naturally found in the yellow flower of Hypericum perforatum (St. John's wort) with antidepressant, potential antiviral, antineoplastic and immunostimulating activities.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
9,11,13,16,18,20-hexahydroxy-5,24-dimethyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(26),2,4(25),5,8,10,12,14(28),15(27),16,18,20,23-tridecaene-7,22-dione
CAS number
548-04-9 CAS number cross-checkedOther or deprecated CAS: 1372719-41-9
EC numbers
208-941-0, 614-798-9
Molecular formula
C30H16O8
UNII
7V2F1075HD
MDL number
MFCD00016683
INCI name
HYPERICUM PERFORATUM OIL
InChIKey
YDOIFHVUBCIUHF-UHFFFAOYSA-N
InChI
InChI=1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,33-38H,1-2H3
SMILES (canonical and isomeric)
CC1=CC(=O)C2=C(C3=C(C=C(C4=C3C5=C2C1=C6C(=CC(=O)C7=C(C8=C(C=C(C4=C8C5=C67)O)O)O)C)O)O)O

Synonyms

  • Hypericum red
  • hypericine
  • Cyclosan
  • hipericina
  • Mycoporphyrin
  • Hyperizin
  • 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione
  • hipericin
  • VIMRxyn
  • Cyclo-Werol
  • Hypericin & Visible light
  • 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethylnaphthodianthrone
  • Hypericin (USAN)
  • Phenanthro[1,10,9,8-opqra]perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-
  • hexahydroxy(dimethyl)[?]dione
  • 1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione
  • 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro(1,10,9,8-opqra)perylene-7,14-dione
  • Phenanthro(1,10,9,8-opqra)perylene-7,14-dione, 1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-
  • Hypericina
  • Cyclo werro
  • (component of) Hypericum spp (st. John's wort)
  • Hypericum perforatum
  • 4,5,7,4',5',7'-Hexahydroxy-2,2'-dimethyl-mesonapthtodianthron
  • BiomolKI2_000040
  • Hypericin from Hypericum perforatum
Show all 32 synonyms
  • HSCI1_000202
  • WHO 11835
  • Hypericin from Hypericum perforatum, ~95% (HPLC)
  • Hypericin, primary pharmaceutical reference standard
  • 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione, 9CI
  • 1,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro [1,10,9,8-opqra]perylene-7,14-dione P-conformer
  • Phenanthro[1,9,8-opqra]perylene-7,14-dione,1,3,4,6,8,13-hexahydroxy-10,11-dimethyl-, stereoisomer

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
504.45 g/molcalc.
Exact mass
504.0845 Dacalc.
LogP (octanol/water)
5.08calc.
Topological polar surface area
155.5 Ųcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
0calc.
Heavy atoms
38calc.
Rings
8calc.
Aromatic rings
8calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1ccc2c3ccc(=O)c4cc5cccc6c7cccc8cc1c2c(c87)c(c56)c43

O=c1ccc2c3ccc(=O)c4cc5cccc6c7cccc8cc1c2c(c87)c(c56)c43

8 rings, 30 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Hypericin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 64 suppliers
30 of 30 offers

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Where suppliers are based

64 suppliers in 10 countries

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Hypericin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name HYPERICUM PERFORATUM OIL(skin conditioning - emollient)

Roles

  • anti-HIV agent
  • antidepressant
  • antimicrobial agent
  • antineoplastic agent
  • antipsoriatic
  • antiviral agent
  • central nervous system drug
  • dermatologic drug
  • pharmaceutical
  • psychotropic drug

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning - emollient

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Hypericin is traded under.

HS 2907.29Indicative HS code

Polyphenols, phenol-alcohols, other

World exports in 2024
$535M
−27.0% vs 2023, imports $565M
2019 to 2024
Top exporters
  1. India * partner reported17.7%
  2. Germany16.5%
  3. Japan15.8%
Top importers
  1. United States13.1%
  2. Japan8.0%
  3. Belgium7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Hypericin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Hypericin, based on the data on this page

What is Hypericin?

Hypericin is a carbopolycyclic compound. It has a role as an antidepressant. It derives from a hydride of a bisanthene.

What is the CAS number of Hypericin?

The CAS registry number of Hypericin is 548-04-9. Other or deprecated CAS numbers: 1372719-41-9.

What is the molecular formula and weight of Hypericin?

The molecular formula of Hypericin is C30H16O8 and its molar mass is 504.45 g/mol.

What is Hypericin used for?

Known uses and roles of Hypericin include emollients in cosmetics and personal care, anti-hiv agent, antidepressant, antimicrobial agent, antineoplastic agent and 8 more.

Is Hypericin hazardous?

No GHS hazard classification for Hypericin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Hypericin?

Hypericin is usually classified under HS code 290729 (Polyphenols, phenol-alcohols, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Hypericin?

CompoundList lists 64 suppliers of Hypericin in China, United States, United Kingdom, Germany and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Hypericin?

Suppliers quote Hypericin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Hypericin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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