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Alkaloids

Ibogaine

Also known as Endabuse, (-)-Ibogaine, NIH 10567

CAS 83-74-9Formula C20H26N2OMolar mass 310.44 g/molEC 201-498-4
GHS signal word: Warning. Pictograms: Harmful or irritant 1 supplier listed
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Ibogaine chemical structure, C20H26N2O, CAS 83-74-9
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Solid
Melting point
148 °C
Solubility
Soluble in chloroform
HS code
293979
Category
Alkaloids
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Typical packagingIllustrative packaging image, not the actual product

What is Ibogaine?

Plain description, key identifiers and synonyms

Ibogaine is an organic heteropentacyclic compound that is ibogamine in which the indole hydrogen para to the indole nitrogen has been replaced by a methoxy group. It has a role as a oneirogen, an inhibitor, a hallucinogen and a plant metabolite. It is an aromatic ether, an organic heteropentacyclic compound and a monoterpenoid indole alkaloid. It is functionally related to an ibogamine. It is a conjugate base of an ibogaine(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1R,15R,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene
CAS number
83-74-9 CAS number cross-checked
EC number
201-498-4
Molecular formula
C20H26N2O
UNII
3S814I130U
InChIKey
HSIBGVUMFOSJPD-CFDPKNGZSA-N
InChI
InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1
Canonical SMILES
CCC1CC2CC3c4[nH]c5ccc(OC)cc5c4CCN(C2)C13
Isomeric SMILES
CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC

Synonyms

  • Endabuse
  • (-)-Ibogaine
  • NIH 10567
  • (1R,15R,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo(13.3.1.02,10.04,9.013,18)nonadeca-2(10),4(9),5,7-tetraene
  • (1R,15R,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene
  • 12 Methoxyibogamine
  • 12-Methoxyibogamine
  • Ibogain
  • (5beta)-12-methoxyibogamine
  • Tabernanthe iboga
  • DEA No. 7260
  • HJM
  • (6xi)-12-Methoxyibogamine
  • (18R)-12-methoxyibogamine
  • 7-Ethyl-6,6beta,7,8,9,10,12,13-octahydro-2-methoxy-6,9-methano-5H-pyrido(1',2':1,2)azepino(5,4-b)indole
  • (6R,6aS,7S,9R,11S)-7-ethyl-2-methoxy-6,6a,7,8,9,10,12,13-octahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Solidexp.
Melting point
148 °Cexp.
Solubility
Soluble in chloroformexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
310.44 g/molcalc.
Exact mass
310.2045 Dacalc.
LogP (octanol/water)
3.94calc.
Topological polar surface area
28.26 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
2calc.
Heavy atoms
23calc.
Rings
6calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c3c([nH]c2c1)C1CC2CCC1N(CC3)C2

c1ccc2c3c([nH]c2c1)C1CC2CCC1N(CC3)C2

6 rings, 19 atoms.

45 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ibogaine suppliers

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  • ChemFaces
    China, WuhanUnclaimed profile
    IbogaineGrade, purity and minimum order on request
    Price on request
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Where suppliers are based

1 supplier in 1 country

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Ibogaine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Ibogaine is a Schedule I controlled substance.

Schedule I Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has no currently accepted medical use in treatment in the United States, and (C) There is a lack of accepted safety for use of the drug or other substance under medical supervision.

Iboga extracts said to be used by African natives while stalking game, to enable them to remain motionless for as long as 2 days while retaining mental alertness. (Iboga extracts).

Therapeutic category: Cardiotonic. Diagnostic aid (glaucoma).

In Gabon and elsewhere in West Central Africa, ibogaine is ingested in the form of scrapings of Tabernanthe iboga root bark. The ritual aim of eating iboga has been conceptualized as "binding"' the binding across time through ancestral contact, or binding participants socially on the basis of a common shared experience of a distinctive consciousness and system of belief.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Excitatory Amino Acid Antagonists
  • Hallucinogens

Roles

  • central nervous system drug
  • eukaryotic metabolite
  • hallucinogen
  • inhibitor
  • metabolite
  • oneirogen
  • pharmaceutical
  • plant metabolite
  • psychotropic drug

How it is made

Isolation from root (1.27%), rootbark (2 to 6%), stems (1.95%) and leaves (0.35%) of the shrub Tabernanthe iboga Baill., Apocynaceae, found in Africa.

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ibogaine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ibogaine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ibogaine, based on the data on this page

What is Ibogaine?

Ibogaine is an organic heteropentacyclic compound that is ibogamine in which the indole hydrogen para to the indole nitrogen has been replaced by a methoxy group. It has a role as a oneirogen, an inhibitor, a hallucinogen and a plant metabolite.

What is the CAS number of Ibogaine?

The CAS registry number of Ibogaine is 83-74-9.

What is the molecular formula and weight of Ibogaine?

The molecular formula of Ibogaine is C20H26N2O and its molar mass is 310.44 g/mol.

What is Ibogaine used for?

Ibogaine is a Schedule I controlled substance. Schedule I Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has no currently accepted medical use in treatment in the United States, and (C) There is a lack of accepted safety for use of the drug or othe…

Is Ibogaine hazardous?

Ibogaine carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ibogaine?

Ibogaine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ibogaine?

CompoundList lists 1 supplier of Ibogaine in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ibogaine?

Suppliers quote Ibogaine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ibogaine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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