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Indapamide chemical structure, C16H16ClN3O3S, CAS 26807-65-8
2D chemical structure

Key facts

What buyers check first

CAS number
26807-65-8
Formula
C16H16ClN3O3S
Molar mass
365.84 g/mol
EC number
248-012-7
HS code
293590
Category
Cardiovascular and metabolic drugs

What is Indapamide?

Plain description, key identifiers and synonyms

Indapamide is a sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine. It has a role as a diuretic and an antihypertensive agent. It is a member of indoles, a sulfonamide and an organochlorine compound. It is functionally related to a benzamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide
CAS number
26807-65-8 CAS number cross-checked
EC number
248-012-7
Molecular formula
C16H16ClN3O3S
UNII
F089I0511L
MDL number
MFCD00079375
InChIKey
NDDAHWYSQHTHNT-UHFFFAOYSA-N
InChI
InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)
SMILES (canonical and isomeric)
CC1CC2=CC=CC=C2N1NC(=O)C3=CC(=C(C=C3)Cl)S(=O)(=O)N

Synonyms

  • Indamol
  • Veroxil
  • Lozol
  • Fludex
  • Indaflex
  • Ipamix
  • Noranat
  • Tandix
  • Bajaten
  • Natrilix
  • Tertensif
  • Arifon
  • Damide
  • Indapamida
  • Metindamide
  • Natrix
  • flupamid
  • indamide
  • Indapamidum
  • Fludin
  • Lorvas
  • Flubest
  • 4-chloro-N-(2-methyl-2,3-dihydroindol-1-yl)-3-sulfamoylbenzamide
  • SE 1520
  • 4-Chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide
Show all 38 synonyms
  • Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)-
  • 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide
  • Ethibide xl
  • Natrilix sr
  • Cardide sr
  • Indipam xl
  • Mapemid xl
  • Tensaid xl
  • Varbim xl
  • Rawel xl
  • Nindaxa 2.5
  • Opumide 2.5
  • Indaxa 2.5

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
365.84 g/molcalc.
Exact mass
365.0601 Dacalc.
LogP (octanol/water)
2.08calc.
Topological polar surface area
92.5 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
24calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.19calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NN1CCc2ccccc21)c1ccccc1

O=C(NN1CCc2ccccc21)c1ccccc1

3 rings, 18 atoms.

8 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Indapamide suppliers

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Indapamide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Antihypertensive Agents
  • Diuretics
  • Sodium Chloride Symporter Inhibitors

Roles

  • antihypertensive agent
  • cardiovascular drug
  • diuretic
  • hypoglycemic agent
  • immunomodulator
  • immunosuppressive agent
  • pharmaceutical

Functional uses

  • Pharmaceutical

Pharmacology

Indapamide is a Thiazide-like Diuretic. The physiologic effect of indapamide is by means of Increased Diuresis.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Indapamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Indapamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Indapamide, based on the data on this page

What is Indapamide?

Indapamide is a sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine. It has a role as a diuretic and an antihypertensive agent. It is a member of indoles, a sulfonamide and an organochlorine compound.

What is the CAS number of Indapamide?

The CAS registry number of Indapamide is 26807-65-8.

What is the molecular formula and weight of Indapamide?

The molecular formula of Indapamide is C16H16ClN3O3S and its molar mass is 365.84 g/mol.

What is Indapamide used for?

Use classes: Pharmaceuticals.

Is Indapamide hazardous?

Indapamide carries the GHS signal word "Warning". Main hazards: suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Indapamide?

Indapamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Indapamide?

CompoundList lists 128 suppliers of Indapamide in China, United States, India, Italy and 20 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Indapamide in India?

15 suppliers in India list Indapamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Indapamide?

Suppliers quote Indapamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Indapamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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