CompoundList
Sign in
Cardiovascular and metabolic drugs

Clopamide

Also known as Clopamidum, Clopamida, Aquex

CAS 636-54-4Formula C14H20ClN3O3SMolar mass 345.85 g/molEC 211-261-7
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 5 suppliers listed
Get quotes Compare 5 suppliers
Clopamide chemical structure, C14H20ClN3O3S, CAS 636-54-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
636-54-4
Formula
C14H20ClN3O3S
Molar mass
345.85 g/mol
EC number
211-261-7
HS code
293590
Category
Cardiovascular and metabolic drugs

What is Clopamide?

Plain description, key identifiers and synonyms

4-chloro-N-[(2S,6R)-2,6-dimethyl-1-piperidinyl]-3-sulfamoylbenzamide is a sulfonamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-chloro-N-[(2S,6R)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide
CAS number
636-54-4 CAS number cross-checkedOther or deprecated CAS: 3563-77-7
EC number
211-261-7
Molecular formula
C14H20ClN3O3S
UNII
17S83WON0I
InChIKey
LBXHRAWDUMTPSE-AOOOYVTPSA-N
InChI
InChI=1S/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+
Canonical SMILES
CC1CCCC(C)N1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1
Isomeric SMILES
C[C@@H]1CCC[C@@H](N1NC(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N)C

Synonyms

  • Clopamidum
  • Clopamida
  • Aquex
  • Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)-, cis-
  • 4-Chloro-N-(2,6-dimethylpiperidino)-3-sulfamoylbenzamide
  • 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide
  • 4-chloro-N-((2R,6S)-2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide
  • Adurix
  • Chlosudimeprimyl
  • 4-Chloro-N-(cis-2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide
  • DT 327
  • Benzamide,3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-, rel-
  • Chlosudimeprinyl
  • Brinaldix,
  • 4-chloro-N-((2S,6R)-2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide
  • 4-chloro-N-[(2S,6R)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide
  • Adurix,
  • Clopamide CRS
  • Aquex,
  • Aquex (TN)
  • Clopamide (Standard)
  • Clopamide (USAN/INN)
  • rel-3-(Aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]benzamide
  • Adurix, Aquex, Brinaldix, Chlosudimeprimyl, Clopamidum, DT 327
  • 4-Chloro-N-[(2RS,6SR)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide
Show all 27 synonyms
  • Clopamide for system suitability CRS
  • Clopamide, European Pharmacopoeia (EP) Reference Standard

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
345.85 g/molcalc.
Exact mass
345.0914 Dacalc.
LogP (octanol/water)
1.9calc.
Topological polar surface area
92.5 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
22calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.5calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NN1CCCCC1)c1ccccc1

O=C(NN1CCCCC1)c1ccccc1

2 rings, 15 atoms, the N-(Piperidin-1-yl)benzenecarboximidic acid ring system.

16 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (15)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Clopamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 5 suppliers
5 of 5 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

5 suppliers in 2 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Clopamide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Diuretics

Roles

  • cardiovascular drug
  • pharmaceutical

Pharmacology

Clopamide is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity. Clopamide appears to work in a similar manner as the thiazide diuretics and has a similar potency as chlorothiazide and hydrochlorothiazide.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Clopamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Clopamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Clopamide, based on the data on this page

What is Clopamide?

4-chloro-N-[(2S,6R)-2,6-dimethyl-1-piperidinyl]-3-sulfamoylbenzamide is a sulfonamide.

What is the CAS number of Clopamide?

The CAS registry number of Clopamide is 636-54-4. Other or deprecated CAS numbers: 3563-77-7.

What is the molecular formula and weight of Clopamide?

The molecular formula of Clopamide is C14H20ClN3O3S and its molar mass is 345.85 g/mol.

What is Clopamide used for?

Known uses and roles of Clopamide include antihypertensives in pharmaceuticals, cardiovascular drug, pharmaceutical and diuretics.

Is Clopamide hazardous?

Clopamide carries the GHS signal word "Danger". Main hazards: may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Clopamide?

Clopamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Clopamide?

CompoundList lists 5 suppliers of Clopamide in United States and China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Clopamide?

Suppliers quote Clopamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Clopamide

Get quotes for Clopamide

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Clopamide
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Clopamide with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/clopamide-636-54-4" title="Clopamide structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Cardiovascular and metabolic drugs or HS code 293590

5 suppliers
Free quotes, contact stays private
Get quotes