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Analgesics and anti-inflammatories

Isoxicam

Also known as Maxicam, Isoxicamum, Isoxicamo

CAS 34552-84-6Formula C14H13N3O5SMolar mass 335.34 g/molEC 252-084-5
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Isoxicam chemical structure, C14H13N3O5S, CAS 34552-84-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
34552-84-6
Formula
C14H13N3O5S
Molar mass
335.34 g/mol
EC number
252-084-5
HS code
293590
Category
Analgesics and anti-inflammatories

What is Isoxicam?

Plain description, key identifiers and synonyms

Isoxicam is a monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Stevens-Johnson syndrome. It has a role as a non-steroidal anti-inflammatory drug and an antirheumatic drug. It is a monocarboxylic acid amide, a benzothiazine and a member of isoxazoles.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide
CAS number
34552-84-6 CAS number cross-checked
EC number
252-084-5
Molecular formula
C14H13N3O5S
UNII
8XU734C4NG
MDL number
MFCD00079374
InChIKey
YYUAYBYLJSNDCX-UHFFFAOYSA-N
InChI
InChI=1S/C14H13N3O5S/c1-8-7-11(16-22-8)15-14(19)12-13(18)9-5-3-4-6-10(9)23(20,21)17(12)2/h3-7,18H,1-2H3,(H,15,16,19)
SMILES (canonical and isomeric)
CC1=CC(=NO1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O

Synonyms

  • Maxicam
  • Isoxicamum
  • Isoxicamo
  • 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-, 1,1-dioxide
  • 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
  • 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide
  • 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide
  • 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
  • 4-Hydroxy-2-methyl-N-(5-methylisoxazol-3-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide
  • 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
  • Pacyl (antiinflammatory)
  • 4-hydroxy-3-(5-methyl-3-isoxazolylcarbamoyl)-2-methyl-2H-1,2-benzothiazine 1,1-dioxide
  • 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide, Floxicam, Pacyl, Pacyl (antiinflammatory), Vectren, W 8495
  • Maxicam (TN)
  • Isoxicam (Standard)
  • Isoxicam (USAN/INN)
  • Isoxicam, analytical standard
  • DivK1c_000661
  • N-(5-methyl-3-isoxazolyl)-4-hydroxy-2-methyl-2H-1,2-benzthiazine-3-carboxamide 1,1-dioxide
  • (4-hydroxy-2-methyl-1,1-dioxobenzo[e]1,2-thiazin-3-yl)-N-(5-methylisoxazol-3-y l)carboxamide
  • 4-Hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxamide
  • 4-Hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-1?6,2-benzothiazine-3-carboxamide
  • 4-hydroxy-2-methyl-N-(5-methylisoxazol-3-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
335.34 g/molcalc.
Exact mass
335.0576 Dacalc.
LogP (octanol/water)
1.48calc.
Topological polar surface area
112.7 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
2calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.14calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1ccon1)C1=Cc2ccccc2S(=O)(=O)N1

O=C(Nc1ccon1)C1=Cc2ccccc2S(=O)(=O)N1

3 rings, 20 atoms.

No other chemical in our database has this scaffold.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Isoxicam suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers

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Where suppliers are based

4 suppliers in 3 countries

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Isoxicam price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal

Roles

  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Isoxicam is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Isoxicam is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Isoxicam, based on the data on this page

What is Isoxicam?

Isoxicam is a monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Stevens-Johnson syndrome.

What is the CAS number of Isoxicam?

The CAS registry number of Isoxicam is 34552-84-6.

What is the molecular formula and weight of Isoxicam?

The molecular formula of Isoxicam is C14H13N3O5S and its molar mass is 335.34 g/mol.

What is Isoxicam used for?

Use classes: Pharmaceuticals.

Is Isoxicam hazardous?

No GHS hazard classification for Isoxicam is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Isoxicam?

Isoxicam is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Isoxicam?

CompoundList lists 4 suppliers of Isoxicam in China, Hong Kong and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Isoxicam?

Suppliers quote Isoxicam on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Isoxicam

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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