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Central nervous system drugs

Lacosamide

Also known as Erlosamide, Vimpat, Harkoseride

CAS 175481-36-4Formula C13H18N2O3Molar mass 250.30 g/molEC 605-756-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant 127 suppliers listed Drug substance
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Lacosamide chemical structure, C13H18N2O3, CAS 175481-36-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
175481-36-4
Formula
C13H18N2O3
Molar mass
250.30 g/mol
EC number
605-756-0
HS code
292429
Category
Central nervous system drugs

What is Lacosamide?

Plain description, key identifiers and synonyms

Lacosamide is a N-acyl-amino acid.

Lacosamide is an anticonvulsant compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2-acetamido-N-benzyl-3-methoxypropanamide
CAS number
175481-36-4 CAS number cross-checked
EC number
605-756-0
Molecular formula
C13H18N2O3
UNII
563KS2PQY5
MDL number
MFCD08272557
InChIKey
VPPJLAIAVCUEMN-GFCCVEGCSA-N
InChI
InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
Canonical SMILES
COCC(NC(C)=O)C(=O)NCc1ccccc1
Isomeric SMILES
CC(=O)N[C@H](COC)C(=O)NCC1=CC=CC=C1

Synonyms

  • Erlosamide
  • Vimpat
  • Harkoseride
  • SPM 927
  • (r)-lacosamide 1
  • Motpoly
  • Lacosamida
  • ADD 234037
  • Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
  • (2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide
  • (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
  • (+)-(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide
  • (2R)-2-acetamido-3-methoxy-N-(phenylmethyl)propanamide
  • lacosamidum
  • Motpoly XR
  • N benzyl AcMeOPrNH2
  • N-benzyl-AcMeOPrNH2
  • Lacosamide Oral Solution
  • (2R)-N-benzyl-2-acetamido-3-methoxypropanamide
  • N benzyl 2 acetamido 3 methoxypropionamide
  • ()-(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide
  • (R)-2-acetamido-N-benzyl-3-methoxypropanamide
  • (2R)-2-acetamido-N-benzyl-3-methoxypropanamide
  • ADD 243037
  • N~2~-Acetyl-N-benzyl-O-methyl-D-serinamide
Show all 33 synonyms
  • (R)-2-Acetylamino-N-benzyl-3-methoxy-propionamide
  • ertosamide
  • harkeroside
  • Lacosamide cv
  • Lacosamide?
  • Lacosamide CRS
  • Lacosamide racemate
  • Vimpat (TN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
250.30 g/molcalc.
Exact mass
250.1317 Dacalc.
LogP (octanol/water)
0.45calc.
Topological polar surface area
67.43 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
18calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.39calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H301Toxic if swallowed.
  • H319Causes serious eye irritation.
Precautionary statements (11)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lacosamide suppliers

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All 127 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

127 suppliers in 19 countries

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Lacosamide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Anticonvulsants
  • Voltage-Gated Sodium Channel Blockers

Roles

  • analgesic
  • anticonvulsant
  • antidepressant
  • antineoplastic agent
  • antipsychotic agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • pharmaceutical
  • protective agent
  • psychotropic drug
  • renoprotective agent
  • tranquilizing drug

Pharmacology

The physiologic effect of lacosamide is by means of Decreased Central Nervous System Disorganized Electrical Activity.

Regulatory status

Inventories, regulations and trade controls that list this substance

Controls

  • US DEA controlled substance or listed chemical

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lacosamide is traded under.

HS 2924.29Indicative HS code

Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$5.69B
−5.1% vs 2023, imports $5.8B
2019 to 2024
Top exporters
  1. China32.3%
  2. Switzerland * partner reported13.6%
  3. Norway * partner reported12.8%
Top importers
  1. United States15.9%
  2. Ireland15.8%
  3. Germany11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lacosamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lacosamide, based on the data on this page

What is Lacosamide?

Lacosamide is a N-acyl-amino acid.

What is the CAS number of Lacosamide?

The CAS registry number of Lacosamide is 175481-36-4.

What is the molecular formula and weight of Lacosamide?

The molecular formula of Lacosamide is C13H18N2O3 and its molar mass is 250.30 g/mol.

What is Lacosamide used for?

Known uses and roles of Lacosamide include cns agents in pharmaceuticals, analgesic, anticonvulsant, antidepressant, antineoplastic agent and 11 more.

Is Lacosamide hazardous?

Lacosamide carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lacosamide?

Lacosamide is usually classified under HS code 292429 (Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lacosamide?

CompoundList lists 127 suppliers of Lacosamide in India, China, United States, Germany and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lacosamide in India?

46 suppliers in India list Lacosamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lacosamide?

Suppliers quote Lacosamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lacosamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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