Lisinopril
Also known as Prinivil, Zestril, Lisinopril anhydrous
Key facts
What buyers check first
- CAS number
- 76547-98-3
- Formula
- C21H31N3O5
- Molar mass
- 405.50 g/mol
- EC number
- 278-488-1
- HS code
- 293399
- Category
- Cardiovascular and metabolic drugs
What is Lisinopril?
Plain description, key identifiers and synonyms
Lisinopril is a dipeptide. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It contains a L-lysine residue and a L-prolino group.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
- CAS number
- 76547-98-3 CAS number cross-checkedOther or deprecated CAS: 77726-95-5, 83915-83-7
- EC numbers
- 278-488-1, 934-016-2
- Molecular formula
- C21H31N3O5
- UNII
- 7Q3P4BS2FD
- MDL number
- MFCD00214086
- InChIKey
- RLAWWYSOJDYHDC-BZSNNMDCSA-N
- InChI
- InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1
- Canonical SMILES
- NCCCCC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CCCC1C(=O)O
- Isomeric SMILES
- C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O
Synonyms
- Prinivil
- Zestril
- Lisinopril anhydrous
- Lysinopril
- Carace
- Novatec
- Lisinoprilum
- Qbrelis
- [N2-[(S)-1-carboxy-3-phenylpropyl]-l-lysyl-l-proline
- N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
- N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
- (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
- L-Proline, N2-((1S)-1-carboxy-3-phenylpropyl)-L-lysyl-
- (S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline
- Lisinoprilum (Latin)
- L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)-
- (2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
- L-Proline, 1-(n(sup 2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-
- 1-(N(sup 2)-((S)-1-carboxy-3-phenylpropyl)-l-lysyl)-l-proline
- (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid
- (N2-((S)-1-carboxy-3-phenylpropyl)-L-lysyl-L-proline
- L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-
- Lisinoril
- Lisopress
- (2S)-1-((2S)-6-amino-2-(((1S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid
Show all 37 synonymsShow fewer synonyms
- (2S)-1-((2S)-6-amino-2-(((2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl)amino)hexanoyl)pyrrolidine-2-carboxylic acid
- L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-
- L-Proline, 1-(N(sup 2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-
- N2-((1S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline, Dihydrate
- Ranolip
- Linopril
- Tensopril
- Acercomp
- Inhibril
- Lisipril
- Noperten
- Presiten
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 405.50 g/molcalc.Computed value |
|---|---|
| Exact mass | 405.2264 Dacalc.Computed value |
| LogP (octanol/water) | 1.24calc.Computed value |
| Topological polar surface area | 133 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 12calc.Computed value |
| Heavy atoms | 29calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.57calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H360May damage fertility or the unborn child.
- H360DMay damage the unborn child.
- H361Suspected of damaging fertility or the unborn child.
- H362May cause harm to breast-fed children.
- H373May cause damage to organs through prolonged or repeated exposure.
Precautionary statements (17)
- P203Obtain, read and follow all safety instructions before use.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P263Avoid contact during pregnancy and while nursing.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P318If exposed or concerned, get medical advice.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidLisinopril suppliers
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- ChinaUnclaimed profileLisinoprilGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileLisinoprilGrade, purity and minimum order on requestPrice on request
- China, HangzhouUnclaimed profileLisinoprilGrade, purity and minimum order on requestPrice on request
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- India, Pune ManufacturerUnclaimed profileLisinoprilGrade Pharma (USP)Price on request
- India ManufacturerUnclaimed profileLisinoprilGrade, purity and minimum order on requestPrice on request
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- India, Ahmedabad ManufacturerUnclaimed profileLisinoprilGrade, purity and minimum order on requestPrice on request
- Spain, Tres Cantos ManufacturerUnclaimed profileLisinoprilGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
113 suppliers in 24 countries
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Lisinopril price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Veterinary medication:.
Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cardiotonic Agents.
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Angiotensin-Converting Enzyme Inhibitors
- Antihypertensive Agents
- Cardiotonic Agents
Roles
- antiatherosclerotic agent
- antihypertensive agent
- antineoplastic agent
- cardiovascular drug
- enzyme inhibitor
- gastrointestinal drug
- hypoglycemic agent
- pharmaceutical
Pharmacology
Lisinopril anhydrous is an Angiotensin Converting Enzyme Inhibitor. The mechanism of action of lisinopril anhydrous is as an Angiotensin-converting Enzyme Inhibitor.
How it is made
Prepn: A.A. Patchett et al., European Patent Office patent 12401, E.E. Harris et al., United States of America patent 4374829 (1980, 1983 both to Merck & Co.).
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Lisinopril is traded under.
Heterocyclic compounds with nitrogen hetero-atom(s) only, other
- Slovenia31.7%
- Italy24.2%
- United States5.0%
* Partner reported figures, a lower bound.
The HS code shown for Lisinopril is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Lisinopril, based on the data on this page
What is Lisinopril?
What is the CAS number of Lisinopril?
What is the molecular formula and weight of Lisinopril?
What is Lisinopril used for?
Is Lisinopril hazardous?
What is the HS code of Lisinopril?
Where can I buy Lisinopril?
Where can I buy Lisinopril in India?
What is the price of Lisinopril?
Guides for buyers
Practical guides that help when you source, ship or handle Lisinopril
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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