CompoundList
Lisinopril chemical structure, C21H31N3O5, CAS 76547-98-3
2D chemical structure

Key facts

What buyers check first

CAS number
76547-98-3
Formula
C21H31N3O5
Molar mass
405.50 g/mol
EC number
278-488-1
HS code
293399
Category
Cardiovascular and metabolic drugs

What is Lisinopril?

Plain description, key identifiers and synonyms

Lisinopril is a dipeptide. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It contains a L-lysine residue and a L-prolino group.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
CAS number
76547-98-3 CAS number cross-checkedOther or deprecated CAS: 77726-95-5, 83915-83-7
EC numbers
278-488-1, 934-016-2
Molecular formula
C21H31N3O5
UNII
7Q3P4BS2FD
MDL number
MFCD00214086
InChIKey
RLAWWYSOJDYHDC-BZSNNMDCSA-N
InChI
InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1
Canonical SMILES
NCCCCC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CCCC1C(=O)O
Isomeric SMILES
C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O

Synonyms

  • Prinivil
  • Zestril
  • Lisinopril anhydrous
  • Lysinopril
  • Carace
  • Novatec
  • Lisinoprilum
  • Qbrelis
  • [N2-[(S)-1-carboxy-3-phenylpropyl]-l-lysyl-l-proline
  • N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
  • N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
  • (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
  • L-Proline, N2-((1S)-1-carboxy-3-phenylpropyl)-L-lysyl-
  • (S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline
  • Lisinoprilum (Latin)
  • L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, (S)-
  • (2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
  • L-Proline, 1-(n(sup 2)-(1-carboxy-3-phenylpropyl)-l-lysyl)-
  • 1-(N(sup 2)-((S)-1-carboxy-3-phenylpropyl)-l-lysyl)-l-proline
  • (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid
  • (N2-((S)-1-carboxy-3-phenylpropyl)-L-lysyl-L-proline
  • L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-
  • Lisinoril
  • Lisopress
  • (2S)-1-((2S)-6-amino-2-(((1S)-1-carboxy-3-phenylpropyl)amino)hexanoyl)pyrrolidine-2-carboxylic acid
Show all 37 synonyms
  • (2S)-1-((2S)-6-amino-2-(((2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl)amino)hexanoyl)pyrrolidine-2-carboxylic acid
  • L-Proline, 1-(N2-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-
  • L-Proline, 1-(N(sup 2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-, dihydrate, (S)-
  • N2-((1S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline, Dihydrate
  • Ranolip
  • Linopril
  • Tensopril
  • Acercomp
  • Inhibril
  • Lisipril
  • Noperten
  • Presiten

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
405.50 g/molcalc.
Exact mass
405.2264 Dacalc.
LogP (octanol/water)
1.24calc.
Topological polar surface area
133 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
12calc.
Heavy atoms
29calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.57calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CNCCCc1ccccc1)N1CCCC1

O=C(CNCCCc1ccccc1)N1CCCC1

2 rings, 18 atoms.

57 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H360May damage fertility or the unborn child.
  • H360DMay damage the unborn child.
  • H361Suspected of damaging fertility or the unborn child.
  • H362May cause harm to breast-fed children.
  • H373May cause damage to organs through prolonged or repeated exposure.
Precautionary statements (17)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lisinopril suppliers

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Lisinopril price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cardiotonic Agents.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • Cardiotonic Agents

Roles

  • antiatherosclerotic agent
  • antihypertensive agent
  • antineoplastic agent
  • cardiovascular drug
  • enzyme inhibitor
  • gastrointestinal drug
  • hypoglycemic agent
  • pharmaceutical

Pharmacology

Lisinopril anhydrous is an Angiotensin Converting Enzyme Inhibitor. The mechanism of action of lisinopril anhydrous is as an Angiotensin-converting Enzyme Inhibitor.

How it is made

Prepn: A.A. Patchett et al., European Patent Office patent 12401, E.E. Harris et al., United States of America patent 4374829 (1980, 1983 both to Merck & Co.).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lisinopril is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lisinopril is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lisinopril, based on the data on this page

What is Lisinopril?

Lisinopril is a dipeptide. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. It contains a L-lysine residue and a L-prolino group.

What is the CAS number of Lisinopril?

The CAS registry number of Lisinopril is 76547-98-3. Other or deprecated CAS numbers: 77726-95-5, 83915-83-7.

What is the molecular formula and weight of Lisinopril?

The molecular formula of Lisinopril is C21H31N3O5 and its molar mass is 405.50 g/mol.

What is Lisinopril used for?

Veterinary medication:. Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cardiotonic Agents. Use classes: Pharmaceuticals.

Is Lisinopril hazardous?

Lisinopril carries the GHS signal word "Danger". Main hazards: causes skin irritation, causes serious eye irritation, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lisinopril?

Lisinopril is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lisinopril?

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Where can I buy Lisinopril in India?

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What is the price of Lisinopril?

Suppliers quote Lisinopril on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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