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Murcko scaffold

Ring system with 2 rings and 18 atoms

58 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
58
With full pages
14
Scaffold SMILES

O=C(CNCCCc1ccccc1)N1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNCCCc1ccccc1)N1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

Lisinopril r,S,S-isomer chemical structure, C21H31N3O5, CAS 85955-59-5
Lisinopril r,S,S-isomer
CAS 85955-59-5C21H31N3O5
CX6Kcq2zkm chemical structure, C18H24N2O5, CAS 192118-19-7
CX6Kcq2zkm
CAS 192118-19-7C18H24N2O5
1-[2-[(1-Carboxy-3-phenyl-propyl)amino]propanoyl]pyrrolidine-2-carboxylic acid chemical structure, C18H24N2O5
1-[2-[(1-Carboxy-3-phenyl-propyl)amino]propanoyl]pyrrolidine-2-carboxylic acid
C18H24N2O5
N-((1R)-1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl-L-proline chemical structure, C20H28N2O5, CAS 76420-74-1
N-((1R)-1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl-L-proline
CAS 76420-74-1C20H28N2O5
Lisinopril dihydrate chemical structure, C21H35N3O7, CAS 83915-83-7
Lisinopril dihydrate
CAS 83915-83-7C21H35N3O7
Lisinopril chemical structure, C21H31N3O5, CAS 76547-98-3
Lisinopril
CAS 76547-98-3C21H31N3O5
Enalapril maleate chemical structure, C24H32N2O9, CAS 76095-16-4
Enalapril maleate
CAS 76095-16-4C24H32N2O9
Enalapril chemical structure, C20H28N2O5, CAS 75847-73-3
Enalapril
CAS 75847-73-3C20H28N2O5
Enalaprilat chemical structure, C18H24N2O5, CAS 76420-72-9
Enalaprilat
CAS 76420-72-9C18H24N2O5
N2-(1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline chemical structure, C21H31N3O5, CAS 77726-95-5
N2-(1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
CAS 77726-95-5C21H31N3O5
(R,S,S)-Enalapril maleate chemical structure, C24H32N2O9, CAS 1356932-13-2
(R,S,S)-Enalapril maleate
CAS 1356932-13-2C24H32N2O9
(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, dihydrate chemical structure, C18H28N2O7, CAS 84680-54-6
(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, dihydrate
CAS 84680-54-6C18H28N2O7
N2-((S)-1-ethoxycarbonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysyl-L-proline chemical structure, C25H34F3N3O6, CAS 103300-91-0
N2-((S)-1-ethoxycarbonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysyl-L-proline
CAS 103300-91-0C25H34F3N3O6
Enalapril mixture with hydrochlorothiazide chemical structure, C27H36ClN5O9S2, CAS 500170-31-0
Enalapril mixture with hydrochlorothiazide
CAS 500170-31-0C27H36ClN5O9S2
L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-, magnesium salt (2:1) chemical structure, C40H54MgN4O10, CAS 338801-65-3
L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-, magnesium salt (2:1)
CAS 338801-65-3C40H54MgN4O10
(2S)-1-((2S)-2-(((1S)-1-(Butoxycarbonyl)-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid chemical structure, C22H32N2O5, CAS 76391-34-9
(2S)-1-((2S)-2-(((1S)-1-(Butoxycarbonyl)-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid
CAS 76391-34-9C22H32N2O5
Enalapril hydrochloride chemical structure, C20H29ClN2O5, CAS 138332-08-8
Enalapril hydrochloride
CAS 138332-08-8C20H29ClN2O5
1-(2S-(1S-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl)-pyrrolidine-2S-carboxylic acid ethyl ester chemical structure, C22H32N2O5, CAS 87420-38-0
1-(2S-(1S-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl)-pyrrolidine-2S-carboxylic acid ethyl ester
CAS 87420-38-0C22H32N2O5
N-Nitroso-enalapril chemical structure, C20H27N3O6, CAS 2994317-06-3
N-Nitroso-enalapril
CAS 2994317-06-3C20H27N3O6
3-Nitrooxypropyl (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylate chemical structure, C23H33N3O8, CAS 690655-41-5
3-Nitrooxypropyl (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylate
CAS 690655-41-5C23H33N3O8
Lisinopril ethyl ester chemical structure, C23H35N3O5, CAS 85955-58-4
Lisinopril ethyl ester
CAS 85955-58-4C23H35N3O5
Enalapril tert-Butyl Ester chemical structure, C24H36N2O5, CAS 108428-39-3
Enalapril tert-Butyl Ester
CAS 108428-39-3C24H36N2O5
N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-D-proline chemical structure, C20H28N2O5, CAS 649756-01-4
N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-D-proline
CAS 649756-01-4C20H28N2O5
Lisinopril hydrate chemical structure, C21H33N3O6, CAS 328395-62-6
Lisinopril hydrate
CAS 328395-62-6C21H33N3O6