Lurasidone (CAS 367514-87-2): price, suppliers and safety

What is Lurasidone?

Plain description, key identifiers and synonyms

Lurasidone is an N-arylpiperazine that is (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-(piperazin-1-ylmethyl)cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione in which position N4 of the piperazine ring is substituted by a 1,2-benzothiazol-3-yl group. Lurasidone is used (generally as the hydrochloride salt) as an atypical antipsychotic for the treatment of schizophrenia. It has a role as an adrenergic antagonist, a serotonergic antagonist, a dopaminergic antagonist and a second generation antipsychotic. It is a dicarboximide, a bridged compound, a N-arylpiperazine and a 1,2-benzisothiazole. It is functionally related to a maleimide. It is a conjugate base of a lurasidone(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name: (1R,2S,6R,7S)-4-[[(1R,2R)-2-[[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
CAS number: 367514-87-2 CAS number cross-checked
EC number: 696-042-8
Molecular formula: C₂₈H₃₆N₄O₂S
UNII: 22IC88528T
MDL number: MFCD14635357
InChIKey: PQXKDMSYBGKCJA-CVTJIBDQSA-N
InChI: InChI=1S/C28H36N4O2S/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2/t18-,19+,20-,21-,24+,25-/m0/s1
Canonical SMILES: O=C1C2C3CCC(C3)C2C(=O)N1CC1CCCCC1CN1CCN(c2nsc3ccccc23)CC1
Isomeric SMILES: C1CC[C@H]([C@@H](C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)[C@H]6[C@@H]7CC[C@@H](C7)[C@H]6C5=O

Synonyms

lurasidona
lurasidonum
SM-13496 FREE BASE
(3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide
(3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(1,2-benzothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione
(1R,2S,6R,7S)-4-[[(1R,2R)-2-[[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
(1S,2R,6S,7R)-4-[[(1R,2R)-2-[[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl]cyclohexyl]methyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Lurasindone
(3aR,4S,7R,7aS)-2-{(1R,2R)-2-(4-(1,2-Benzisothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl}hexahydro-4,7-methano-2H-isoindole-1,3-dione
(3aR,4S,7R,7aS)-2-{(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-ylmethyl]cyclohexylmethyl}hexahydro-4,7-methano-2H-isoindole-1,3-dione
PS34 - Lurasidone
Lurasidone (Standard)
PDSP2_001043
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo[5.2.1.0,2,6]decane-3,5-dione
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}-4-azatricyclo[5.2.1.0?,?]decane-3,5-dione
4,7-Methano-1H-isoindole-1,3(2H)-dione, 2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-, (3aR,4S,7R,7aS)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Flash point	9.7 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight	492.69 g/molcalc.
Exact mass	492.2559 Dacalc.
LogP (octanol/water)	4.26calc.
Topological polar surface area	56.75 Å²calc.
Hydrogen bond donors	0calc.
Hydrogen bond acceptors	6calc.
Rotatable bonds	5calc.
Heavy atoms	35calc.
Rings	7calc.
Aromatic rings	2calc.
Fraction sp3 carbons	0.68calc.
Formal charge	0calc.
Stereocentres	6calc.
Lipinski rule of five	Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

O=C1C2C3CCC(C3)C2C(=O)N1CC1CCCCC1CN1CCN(c2nsc3ccccc23)CC1

7 rings, 35 atoms.

19 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word

Warning

Harmful or irritant

Serious health hazard

Hazard statements

H302 + H332Harmful if swallowed. Harmful if inhaled.
H302Harmful if swallowed.
H317May cause an allergic skin reaction.
H332Harmful if inhaled.
H336May cause drowsiness or dizziness.
H351Suspected of causing cancer.
H361Suspected of damaging fertility or the unborn child.
H413May cause long lasting harmful effects to aquatic life.

Precautionary statements (21)

P203Obtain, read and follow all safety instructions before use.
P261Avoid breathing dust, fume, gas, mist, vapours or spray.
P264Wash skin thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves, protective clothing, eye protection and face protection.
P301 + P317If swallowed: Get medical help.
P302 + P352If on skin: Wash with plenty of water.
P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
P317Get medical help.
P318If exposed or concerned, get medical advice.
P319Get medical help if you feel unwell.
P321Specific treatment (see supplemental first aid instructions on the label).
P330Rinse mouth.
P333 + P317If skin irritation or rash occurs: Get medical help.
P362 + P364Take off contaminated clothing. And wash it before reuse.
P403 + P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lurasidone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 59 suppliers

Verified only30 of 30 offers

Depew Fine Chemical Co., Ltd.
ChinaUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Anhui Sun-wise Pharmaceutical Co., Ltd.
ChinaUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Shanghaizehan biopharma technology co., Ltd
China, ShanghaiUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Shochem (Shanghai) Co., Ltd
ChinaUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Shanghai SynFarm Pharmaceutical Technology Co., Ltd.
China, ShanghaiUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Jinan Million Pharmaceutical Co., Ltd
China, JinanUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Shrenik Pharma Ltd.
India, Mumbai ManufacturerUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Beijing Cooperate Pharmaceutical Co., Ltd
China, BeijingUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Sanjivani Life Science
India, Surat ManufacturerUnclaimed profile
LurasidoneGrade, purity and minimum order on request
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Chemtos
United StatesUnclaimed profile
LurasidoneGrade, purity and minimum order on request
Price on request
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

59 suppliers in 13 countries

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Lurasidone price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Antipsychotic.

Industries and functions

CNS agents in pharmaceuticals

Roles

adrenergic agent
adrenergic antagonist
antagonist
antipsychotic agent
central nervous system depressant
central nervous system drug
dopaminergic agent
dopaminergic antagonist
neurotransmitter agent
pharmaceutical
psychotropic drug
second generation antipsychotic
serotonergic antagonist
serotonergic drug
tranquilizing drug

Pharmacology

Lurasidone is an Atypical Antipsychotic.

How it is made

Preparation: I. Saji et al., European Patent Office patent 464846, eidem, United States of America patent 5532372 (1992, 1996 both to Sumitomo).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lurasidone is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024

$26.7B

+15.0% vs 2023, imports $26.3B

2019 to 2024

Top exporters

Ireland26.3%
China15.7%
Singapore10.3%

Top importers

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lurasidone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Parent and salt forms, stereoisomers, similar structures and isomers

Salt and hydrate forms

Records that share this compound as their parent

Lurasidone hydrochloride chemical structure, C28H37ClN4O2S, CAS 367514-88-3

Lurasidone hydrochloride367514-88-3C₂₈H₃₇ClN₄O₂S105 suppliers

Stereoisomers and isotopic forms

Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)

Lurasidone-d8 chemical structure, C28H36N4O2S, CAS 1132654-54-6

Lurasidone-d81132654-54-6C₂₈H₃₆N₄O₂S

ent-Lurasidone chemical structure, C28H36N4O2S, CAS 1448443-35-3

ent-Lurasidone1448443-35-3C₂₈H₃₆N₄O₂S1 supplier

(3aR,4S,7R,7aS)-2-((cis-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C28H36N4O2S, CAS 1318074-18-8

(3aR,4S,7R,7aS)-2-((cis-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione1318074-18-8C₂₈H₃₆N₄O₂S

(3AR,4R,7S,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C28H36N4O2S, CAS 1318074-25-7

(3AR,4R,7S,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione1318074-25-7C₂₈H₃₆N₄O₂S1 supplier

(3aR,4R,7S,7aS)-2-((cis-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C28H36N4O2S, CAS 1318074-22-4

(3aR,4R,7S,7aS)-2-((cis-2-((4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione1318074-22-4C₂₈H₃₆N₄O₂S

(3AR,4R,7S,7aS)-2-(((1S,2S)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C28H36N4O2S, CAS 1318074-27-9

(3AR,4R,7S,7aS)-2-(((1S,2S)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione1318074-27-9C₂₈H₃₆N₄O₂S

Lurasidone impurity D chemical structure, C28H36N4O2S, CAS 1318074-19-9

Lurasidone impurity D1318074-19-9C₂₈H₃₆N₄O₂S1 supplier

Lurasidone impurity E chemical structure, C28H36N4O2S, CAS 1318074-24-6

Lurasidone impurity E1318074-24-6C₂₈H₃₆N₄O₂S

Similar structures

Nearest neighbours by Morgan fingerprint Tanimoto similarity

Lurasidone metabolite 14283 chemical structure, C28H36N4O3S, CAS 186204-31-9

Lurasidone metabolite 14326 chemical structure, C28H36N4O3S, CAS 186204-33-1

Same formula isomers

Different compounds that share this molecular formula

All isomers

N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-ethylbenzene-1-sulfonamide chemical structure, C28H36N4O2S, CAS 946366-60-5

N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-ethylbenzene-1-sulfonamide946366-60-5C₂₈H₃₆N₄O₂S

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2-phenylethanesulfonamide chemical structure, C28H36N4O2S, CAS 946317-09-5

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2-phenylethanesulfonamide946317-09-5C₂₈H₃₆N₄O₂S

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,4-dimethylbenzenesulfonamide chemical structure, C28H36N4O2S, CAS 1005298-06-5

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,4-dimethylbenzenesulfonamide1005298-06-5C₂₈H₃₆N₄O₂S

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3,4-dimethylbenzenesulfonamide chemical structure, C28H36N4O2S, CAS 946317-03-9

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3,4-dimethylbenzenesulfonamide946317-03-9C₂₈H₃₆N₄O₂S

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,5-dimethylbenzenesulfonamide chemical structure, C28H36N4O2S, CAS 946366-66-1

N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,5-dimethylbenzenesulfonamide946366-66-1C₂₈H₃₆N₄O₂S

N-[(4-Cyclohexyl-5-phenacylsulfanyl-1,2,4-triazol-3-yl)methyl]adamantane-1-carboxamide chemical structure, C28H36N4O2S, CAS 477304-24-8

N-[(4-Cyclohexyl-5-phenacylsulfanyl-1,2,4-triazol-3-yl)methyl]adamantane-1-carboxamide477304-24-8C₂₈H₃₆N₄O₂S

1-(6-Ethoxy-1,3-benzothiazol-2-yl)-N-{4-[(4-methylpiperidin-1-yl)methyl]phenyl}piperidine-3-carboxamide chemical structure, C28H36N4O2S, CAS 902897-27-2

1-(6-Ethoxy-1,3-benzothiazol-2-yl)-N-{4-[(4-methylpiperidin-1-yl)methyl]phenyl}piperidine-3-carboxamide902897-27-2C₂₈H₃₆N₄O₂S

Frequently asked questions

Quick answers about Lurasidone, based on the data on this page

What is Lurasidone?

Lurasidone is an N-arylpiperazine that is (3aR,4S,7R,7aS)-2-{[(1R,2R)-2-(piperazin-1-ylmethyl)cyclohexyl]methyl}hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione in which position N4 of the piperazine ring is substituted by a 1,2-benzothiazol-3-yl group.

What is the CAS number of Lurasidone?

The CAS registry number of Lurasidone is 367514-87-2.

What is the molecular formula and weight of Lurasidone?

The molecular formula of Lurasidone is C28H36N4O2S and its molar mass is 492.69 g/mol.

What is Lurasidone used for?

Therapeutic category: Antipsychotic.

Is Lurasidone hazardous?

Lurasidone carries the GHS signal word "Warning". Main hazards: harmful if swallowed. harmful if inhaled, harmful if swallowed, may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lurasidone?

Lurasidone is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lurasidone?

CompoundList lists 59 suppliers of Lurasidone in China, United States, India, Japan and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lurasidone in India?

7 suppliers in India list Lurasidone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lurasidone?

Suppliers quote Lurasidone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lurasidone

Lurasidone

Key facts

What is Lurasidone?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Hazard statements

Lurasidone suppliers

Where suppliers are based

Send one request to many suppliers

Lurasidone price

Uses and applications

Industries and functions

Roles

Pharmacology

How it is made

Regulatory status

Health and food

HS code and trade data

Global trade

Frequently asked questions

What is Lurasidone?

What is the CAS number of Lurasidone?

What is the molecular formula and weight of Lurasidone?

What is Lurasidone used for?

Is Lurasidone hazardous?

What is the HS code of Lurasidone?

Where can I buy Lurasidone?

Where can I buy Lurasidone in India?

What is the price of Lurasidone?

Guides for buyers

Get quotes for Lurasidone

Key facts

What is Lurasidone?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Hazard statements

Lurasidone suppliers

Where suppliers are based

Send one request to many suppliers

Lurasidone price

Uses and applications

Industries and functions

Roles

Pharmacology

How it is made

Regulatory status

Health and food

HS code and trade data

Global trade

Related chemicals

Salt and hydrate forms

Stereoisomers and isotopic forms

Similar structures

Same formula isomers

Frequently asked questions

What is Lurasidone?

What is the CAS number of Lurasidone?

What is the molecular formula and weight of Lurasidone?

What is Lurasidone used for?

Is Lurasidone hazardous?

What is the HS code of Lurasidone?

Where can I buy Lurasidone?

Where can I buy Lurasidone in India?

What is the price of Lurasidone?

Guides for buyers

Get quotes for Lurasidone