Meclofenamic acid
Also known as meclofenamate, Arquel, 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid
Key facts
What buyers check first
- CAS number
- 644-62-2
- Formula
- C14H11Cl2NO2
- Molar mass
- 296.15 g/mol
- EC number
- 211-419-5
- HS code
- 292249
- Category
- Analgesics and anti-inflammatories
What is Meclofenamic acid?
Plain description, key identifiers and synonyms
Meclofenamic acid is an aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antineoplastic agent, an anticonvulsant, an antirheumatic drug and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is an aminobenzoic acid, an organochlorine compound and a secondary amino compound. It is a conjugate acid of a meclofenamic acid(1-).
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-(2,6-dichloro-3-methylanilino)benzoic acid
- CAS number
- 644-62-2 CAS number cross-checked
- EC number
- 211-419-5
- Molecular formula
- C14H11Cl2NO2
- UNII
- 48I5LU4ZWD
- InChIKey
- SBDNJUWAMKYJOX-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)
- SMILES (canonical and isomeric)
- CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)O)Cl
Synonyms
- meclofenamate
- Arquel
- 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid
- Acido meclofenamico
- Acide meclofenamique
- INF 4668
- Acidum meclofenamicum
- N-(2,6-Dichloro-m-tolyl)anthranilic acid
- Meclomen
- N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid
- 2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid
- N-(2,6-Dichloro-3-methylphenyl)anthranilic acid
- Arquel Tablets
- Benzoic acid, 2-((2,6-dichloro-3-methylphenyl)amino)-
- benzoic acid, 2-[(2,6-dichloro-3-methylphenyl)amino]-
- Arquel Granules
- Meclofenamate, Sodium
- Meclophenamic acid
- Meclomen (free acid)
- 2-(2,6-dichloro-3-methylanilino)benzoic acid
- 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid
- Meclofenamic acid (USAN/INN)
- meclofenamic-acid
- 644-62-2 (free acid)
- Anthranilic acid, N-(2,6-dichloro-m-tolyl)-
Show all 30 synonymsShow fewer synonyms
- JMS
- CL 583
- 2-(2,6-dichloro-3-methyl-anilino)benzoic acid
- 2-(2,6-Dichloro-3-methylphenyl)aminobenzoic acid
- DivK1c_000504
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 296.15 g/molcalc.Computed value |
|---|---|
| Exact mass | 295.0167 Dacalc.Computed value |
| LogP (octanol/water) | 4.74calc.Computed value |
| Topological polar surface area | 49.33 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 2calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 19calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.07calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc(Nc2ccccc2)cc1
2 rings, 13 atoms, the Diphenylamine ring system.
3,181 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
Precautionary statements (5)
- P264Wash skin thoroughly after handling.
- P270Do not eat, drink or smoke when using this product.
- P301 + P317If swallowed: Get medical help.
- P330Rinse mouth.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidMeclofenamic acid suppliers
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- India, Guwahati ManufacturerUnclaimed profileMeclofenamic AcidGrade, purity and minimum order on requestPrice on request
- China, HangzhouUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- United States, Monmouth JunctionUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- Spain, BarcelonaUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- United States, WoburnUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
- United States, SomervilleUnclaimed profileMeclofenamic acidGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
57 suppliers in 15 countries
- United States24
- China16
- Spain3
- Germany2
- United Kingdom2
- Canada1
- and 9 more countries
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Meclofenamic acid price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals, Animal Drugs.
Industries and functions
Pharmacological actions
- Anti-Inflammatory Agents, Non-Steroidal
- Cyclooxygenase Inhibitors
Roles
- analgesic
- anti-inflammatory agent
- anti-inflammatory drug
- anticonvulsant
- antineoplastic agent
- antipyretic
- antirheumatic drug
- central nervous system depressant
- central nervous system drug
- enzyme inhibitor
- lipoxygenase inhibitor
- non-steroidal anti-inflammatory drug
- pharmaceutical
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Meclofenamic acid is traded under.
Amino-acids, other than those containing more than one kind of oxygen function, andโฆ
- United States13.4%
- Germany11.1%
- Japan6.6%
* Partner reported figures, a lower bound.
The HS code shown for Meclofenamic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Meclofenamic acid, based on the data on this page
What is Meclofenamic acid?
What is the CAS number of Meclofenamic acid?
What is the molecular formula and weight of Meclofenamic acid?
What is Meclofenamic acid used for?
Is Meclofenamic acid hazardous?
What is the HS code of Meclofenamic acid?
Where can I buy Meclofenamic acid?
Where can I buy Meclofenamic acid in India?
What is the price of Meclofenamic acid?
Guides for buyers
Practical guides that help when you source, ship or handle Meclofenamic acid
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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