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Insecticides and acaricides

Methoxychlor

Also known as p,p'-Methoxychlor, DMDT, Dimethoxy-DDT

CAS 72-43-5Formula C16H15Cl3O2Molar mass 345.65 g/molEC 108-349-1
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 44 suppliers listed
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Methoxychlor chemical structure, C16H15Cl3O2, CAS 72-43-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless crystals (technical, grey powder)
Melting point
87 °C
Boiling point
Decomposes
Density
1.41 g/cm³ at 25 °C
Solubility
Solubility in water: none
HS code
290930
Category
Insecticides and acaricides
UN number
UN 3077
Illustrative photo, a white jumbo bulk bag of powder in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Methoxychlor?

Plain description, key identifiers and synonyms

Methoxychlor is an organochlorine insecticide. It is functionally related to a 1,1,1-trichloro-2,2-diphenylethane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene
CAS number
72-43-5 CAS number cross-checkedOther or deprecated CAS: 1644449-82-0
EC numbers
108-349-1, 200-779-9
Molecular formula
C16H15Cl3O2
UNII
RIA79UD69L
MDL number
MFCD00000803
InChIKey
IAKOZHOLGAGEJT-UHFFFAOYSA-N
InChI
InChI=1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3
SMILES (canonical and isomeric)
COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)C(Cl)(Cl)Cl

Synonyms

  • p,p'-Methoxychlor
  • DMDT
  • Dimethoxy-DDT
  • Methoxy-DDT
  • Methoxcide
  • Marlate
  • Metox
  • Moxie
  • Maralate
  • Higalmetox
  • Metoksychlor
  • Dianisyl trichloroethane
  • Dianisyltrichlorethane
  • Dimethoxy-DT
  • Mezox K
  • Methoxychlor 2 ec
  • Methoxychlore
  • Rcra waste number U247
  • Methoxo
  • 2,2-Bis(p-anisyl)-1,1,1-trichloroethane
  • Methoxychlor, technical
  • p,p'-DMDT
  • ENT 1,716
  • 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane
  • 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane
Show all 39 synonyms
  • 1,1,1-Trichloro-2,2-bis(p-anisyl)ethane
  • OMS 466
  • 1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane
  • 1-Methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene
  • 1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane
  • 2,2-Di-p-anisyl-1,1,1-trichloroethane
  • 4,4-(2,2,2-Trichloroethylidene)dianisole
  • Ethane, 1,1,1-trichloro-2,2-bis(p-methoxyphenyl)-
  • p,p'-Dimethoxydiphenyltrichloroethane
  • p,p'-Dwumetoksydwufenylotrojchloroetan
  • 1,1'-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene)
  • Ethane, 2,2-bis(p-anisyl)-1,1,1-trichloro-
  • 1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane
  • 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis(4-methoxybenzene)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless crystals (technical, grey powder)exp.
Odour
Slight, fruity odorexp.
Melting point
87 °Cexp.
Boiling point
Decomposesexp.
Density
1.41 g/cm³ at 25 °Cexp.
Solubility
Solubility in water: noneexp.
Vapour pressure
Negligibleexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
345.65 g/molcalc.
Exact mass
344.0138 Dacalc.
LogP (octanol/water)
5.21calc.
Topological polar surface area
18.46 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
4calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cc2ccccc2)cc1

c1ccc(Cc2ccccc2)cc1

2 rings, 13 atoms, the Diphenylmethane ring system.

8,982 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302 + H312 + H332Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H332Harmful if inhaled.
  • H350iMay cause cancer by inhalation.
  • H361Suspected of damaging fertility or the unborn child.
  • H371May cause damage to organs.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (21)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P308 + P316If exposed or concerned: Get emergency medical help immediately.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3077

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Methoxychlor suppliers

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All 44 suppliers
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Where suppliers are based

44 suppliers in 11 countries

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Methoxychlor price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

For methoxychlor (USEPA/OPP PC Code: 034001) there are 0 labels match.

Insecticide.

Therapeutic category (veterinary): Ectoparasiticide.

Widely used because of long residual action against many species of insects and low toxicity to humans and warm-blooded animals. For certain insect pests on fruit and shade trees, vegetables, cattle, and around farm buildings (except poultry houses). Replacement for DDT where application may constitute a hazard to warm-blooded animals or plants. Rarely phytotoxic, and injury is usually negligible even on DDT-susceptible crops such as cucurbits.

Methoxychlor was used as an insecticide effective against a wide range of pests including biting flies, houseflies, mosquito larvae, cockroaches, and chiggers. It was used on field crops, vegetables, fruits, stored grains, livestock, pests, homes, gardens, lakes, and marshes.

Read more

Methoxychlor was also used against the elm bark-beetle vectors of Dutch elm disease. All pesticide uses of methoxychlor were suspended in 2000, and all products are expected to be voluntarily canceled by the end of 2004.

Use classes: Pesticides, Insecticides.

Pharmacological actions

  • Insecticides

Functional uses

  • Biocide

How it is made

Reaction of anisole with chloral in the presence of aluminum chloride or sulfuric acid

Condensation of trichloroacetaldehyde with anisole produces the technical product ...

Commercial preparation by the condensation of anisole with chloral in the presence of sulfuric acid.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Methoxychlor is traded under.

HS 2909.30Indicative HS code

Aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives

World exports in 2024
$470M
−2.2% vs 2023, imports $432M
2019 to 2024
Top exporters
  1. China45.7%
  2. Germany15.7%
  3. India * partner reported9.9%
Top importers
  1. United States14.3%
  2. China11.8%
  3. India * partner reported8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Methoxychlor is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Methoxychlor, based on the data on this page

What is Methoxychlor?

Methoxychlor is an organochlorine insecticide. It is functionally related to a 1,1,1-trichloro-2,2-diphenylethane.

What is the CAS number of Methoxychlor?

The CAS registry number of Methoxychlor is 72-43-5. Other or deprecated CAS numbers: 1644449-82-0.

What is the molecular formula and weight of Methoxychlor?

The molecular formula of Methoxychlor is C16H15Cl3O2 and its molar mass is 345.65 g/mol.

What is Methoxychlor used for?

For methoxychlor (USEPA/OPP PC Code: 034001) there are 0 labels match. Insecticide. Therapeutic category (veterinary): Ectoparasiticide. Widely used because of long residual action against many species of insects and low toxicity to humans and warm-blooded animals.

Is Methoxychlor hazardous?

Methoxychlor carries the GHS signal word "Danger". Main hazards: harmful if swallowed. harmful in contact with skin. harmful if inhaled, harmful if swallowed, harmful in contact with skin. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Methoxychlor?

Methoxychlor is usually classified under HS code 290930 (Aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Methoxychlor?

CompoundList lists 44 suppliers of Methoxychlor in United States, China, United Kingdom, Germany and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Methoxychlor?

Suppliers quote Methoxychlor on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Methoxychlor

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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