Miglitol
Also known as Glyset, (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, Bay m 1099
Key facts
What buyers check first
- Appearance
- White to pale-yellow powder
- Melting point
- 114 ยฐC
- Solubility
- Soluble in water
- HS code
- 293339
- Category
- Cardiovascular and metabolic drugs

What is Miglitol?
Plain description, key identifiers and synonyms
Miglitol is a member of piperidines.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
- CAS number
- 72432-03-2 CAS number cross-checkedOther or deprecated CAS: 1204250-58-7
- EC number
- 276-661-6
- Molecular formula
- C8H17NO5
- UNII
- 0V5436JAQW
- MDL number
- MFCD00867240
- InChIKey
- IBAQFPQHRJAVAV-ULAWRXDQSA-N
- InChI
- InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1
- Canonical SMILES
- OCCN1CC(O)C(O)C(O)C1CO
- Isomeric SMILES
- C1[C@@H]([C@H]([C@@H]([C@H](N1CCO)CO)O)O)O
Synonyms
- Glyset
- (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
- Bay m 1099
- Bay-m-1099
- (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol
- 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))-
- BAY-m 1099
- N-hydroxyethyl-1-desoxynojirimycin
- N-hydroxyethyl-1-desoxy-nojirimycin
- Miglitol (Glyset)
- Miglitolum
- Diastabol
- Seibule
- Miglitolum (Latin)
- Plumarol
- 3,4,5-Piperidinetriol, 1-(2-hydroxyethyl)-2-(hydroxymethyl)-,(2R,3R,4R,5S)-
- N-(2-Hydroxyethyl)-1-deoxynojirimycin
- Glyset (TN)
- BAY1099, BAY-m1099
- Bay 1099
- Diastabol,
- baym1099
- N-hydroxyethyl-1-desoxynojiri
- BAY-m1099
- Miglitol (JP18/USAN/INN)
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | White to pale-yellow powderexp.Measured value |
|---|---|
| Melting point | 114 ยฐCexp.Measured value |
| Solubility | Soluble in waterexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 207.23 g/molcalc.Computed value |
|---|---|
| Exact mass | 207.1107 Dacalc.Computed value |
| LogP (octanol/water) | -3.26calc.Computed value |
| Topological polar surface area | 104.4 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 5calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 14calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 1calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 4calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H314Causes severe skin burns and eye damage.
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H361Suspected of damaging fertility or the unborn child.
Precautionary statements (20)
- P203Obtain, read and follow all safety instructions before use.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
- P302 + P352If on skin: Wash with plenty of water.
- P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P316Get emergency medical help immediately.
- P318If exposed or concerned, get medical advice.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P363Wash contaminated clothing before reuse.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidMiglitol suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- ChinaUnclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
- Price on request
- China ManufacturerUnclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
- Price on request
- Unclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
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- China ManufacturerUnclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
- China, Taizhou ManufacturerUnclaimed profileMiglitolGrade, purity and minimum order on requestPrice on request
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Where suppliers are based
79 suppliers in 14 countries
- China33
- United States28
- United Kingdom4
- Germany2
- Canada1
- Spain1
- and 8 more countries
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Miglitol price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Enzyme Inhibitors
- Glycoside Hydrolase Inhibitors
- Hypoglycemic Agents
Roles
- hypoglycemic agent
- pharmaceutical
Pharmacology
Miglitol is an alpha-Glucosidase Inhibitor. The mechanism of action of miglitol is as an alpha Glucosidase Inhibitor.
How it is made
One method involves nojirimycin, a natural product obtainable from the leaves of the mulberry tree (Morus elba, Morus bombycis, or Morus nigra). Nojirimycin retains the configuration of D-glucose with the ether linkage replaced by a secondary amino group. The hydrogen atom on carbon-1 is removed by regioselective oxidation with Gluconobacter oxydans to form 1-deoxynojirimycin. The amine hydrogen atom is replaced by a hydroxyethyl group to form the product.
Preparation: B. Junge et al., DE 2758025, eidem, US 4639436 (1979, 1987 both to Bayer AG)
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Miglitol is traded under.
Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structureโฆ
- Germany14.2%
- United States12.8%
- Brazil10.1%
* Partner reported figures, a lower bound.
The HS code shown for Miglitol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Miglitol, based on the data on this page
What is Miglitol?
What is the CAS number of Miglitol?
What is the molecular formula and weight of Miglitol?
What is Miglitol used for?
Is Miglitol hazardous?
What is the HS code of Miglitol?
Where can I buy Miglitol?
Where can I buy Miglitol in India?
What is the price of Miglitol?
Guides for buyers
Practical guides that help when you source, ship or handle Miglitol
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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