CompoundList
Sign in
Central nervous system drugs

Mpep

Also known as 2-Methyl-6-(phenylethynyl)pyridine, 2-methyl-6-(2-phenylethynyl)pyridine, 6-Methyl-2-(phenylethynyl)pyridine

CAS 96206-92-7Formula C14H11NMolar mass 193.25 g/mol
14 suppliers listed
Get quotes Compare 14 suppliers
Mpep chemical structure, C14H11N, CAS 96206-92-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
96206-92-7
Formula
C14H11N
Molar mass
193.25 g/mol
HS code
293339
Category
Central nervous system drugs

What is Mpep?

Plain description, key identifiers and synonyms

2-methyl-6-(phenylethynyl)pyridine is a methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. It has a role as an anxiolytic drug and a metabotropic glutamate receptor antagonist. It is a member of methylpyridines and an acetylenic compound. It is a conjugate base of a 2-methyl-6-(phenylethynyl)pyridinium(1+). It derives from a hydride of an acetylene.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-methyl-6-(2-phenylethynyl)pyridine
CAS number
96206-92-7 CAS number cross-checked
Molecular formula
C14H11N
UNII
7VC0YVI27Y
MDL number
MFCD03787983
InChIKey
NEWKHUASLBMWRE-UHFFFAOYSA-N
InChI
InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
SMILES (canonical and isomeric)
CC1=NC(=CC=C1)C#CC2=CC=CC=C2

Synonyms

  • 2-Methyl-6-(phenylethynyl)pyridine
  • 2-methyl-6-(2-phenylethynyl)pyridine
  • 6-Methyl-2-(phenylethynyl)pyridine
  • MPEP cpd
  • Pyridine, 2-methyl-6-(phenylethynyl)-
  • 2-methyl-6-(phenylethynyl)-pyridine
  • Tocris-1212
  • MPEP?
  • 2-Picoline, 6-phenylethynyl-
  • 2-Methyl-6-phenylethynyl-pyridine
  • 2-methyl-6-(phenyl-ethynyl)pyridine
  • 6-methyl-2-(2-phenylethynyl)pyridine
  • Sdccgsbi-0050716.p002
  • Pyridine, 6-methyl-2-(phenylethynyl)-
  • 2-Methyl-6-phenylethynyl-pyridine(MPEP)
  • [3H]-2-methyl-6-(phenylethynyl)-pyridine
  • 2-methyl-6-(phenylethynyl)pyridine (mpep)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
193.25 g/molcalc.
Exact mass
193.0891 Dacalc.
LogP (octanol/water)
2.79calc.
Topological polar surface area
12.89 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
15calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C(#Cc1ccccn1)c1ccccc1

C(#Cc1ccccn1)c1ccccc1

2 rings, 14 atoms, the 2-(2-Phenylethynyl)pyridine ring system.

111 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Mpep suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 14 suppliers
14 of 14 offers
  • AgroIntelBioScan.com
    Singapore, SingaporeUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Alinda Chemical Trade Company Ltd
    Hong Kong, Hong KongUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Angel Pharmatech Ltd.
    China, ShanghaiUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Apexmol
    China, ChongqingUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • BioChemPartner
    China, ShangHaiUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • BioCrick
    China, ChengduUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Chemenu. Inc.
    China, ShanghaiUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Excenen Pharmatech Co., Ltd.
    China, GuangzhouUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Glixx Labs, Inc
    United States, HopkintonUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View
  • Life Chemicals
    Canada, Niagara-on-the-LakeUnclaimed profile
    MpepGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

14 suppliers in 5 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Mpep price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Anxiety Agents
  • Excitatory Amino Acid Antagonists

Roles

  • antagonist
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • metabotropic glutamate receptor antagonist
  • pharmaceutical
  • psychotropic drug
  • tranquilizing drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mpep is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Mpep is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mpep, based on the data on this page

What is Mpep?

2-methyl-6-(phenylethynyl)pyridine is a methylpyridine that coinsists of 2-methylp[yridine bearing an additional phenylethynyl group at position 6. Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors.

What is the CAS number of Mpep?

The CAS registry number of Mpep is 96206-92-7.

What is the molecular formula and weight of Mpep?

The molecular formula of Mpep is C14H11N and its molar mass is 193.25 g/mol.

What is Mpep used for?

Known uses and roles of Mpep include cns agents in pharmaceuticals, biochemical and pharmacological tools in research and laboratory, antagonist, anxiolytic drug, central nervous system depressant and 7 more.

Is Mpep hazardous?

No GHS hazard classification for Mpep is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Mpep?

Mpep is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mpep?

CompoundList lists 14 suppliers of Mpep in China, United States, Canada, Hong Kong and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Mpep?

Suppliers quote Mpep on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Mpep

Get quotes for Mpep

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Mpep
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Mpep with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/mpep-96206-92-7" title="Mpep structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Central nervous system drugs or HS code 293339

14 suppliers
Free quotes, contact stays private
Get quotes