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Food preservatives

Natamycin

Also known as pimaricin, Myprozine, Natacyn

CAS 7681-93-8Formula C33H47NO13Molar mass 665.73 g/molEC 231-683-5
92 suppliers listed Drug substance
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Natamycin chemical structure, C33H47NO13, CAS 7681-93-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
7681-93-8
Formula
C33H47NO13
Molar mass
665.73 g/mol
Physical form
Powder
HS code
294190
Category
Food preservatives
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Natamycin?

Plain description, key identifiers and synonyms

Natamycin is a polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
CAS number
7681-93-8 CAS number cross-checkedOther or deprecated CAS: 52882-37-8
EC number
231-683-5
Molecular formula
C33H47NO13
UNII
8O0C852CPO
MDL number
MFCD00135085
INCI name
NATAMYCIN
InChIKey
NCXMLFZGDNKEPB-FFPOYIOWSA-N
InChI
InChI=1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1
Canonical SMILES
CC1CC=CC=CC=CC=CC(OC2OC(C)C(O)C(N)C2O)CC2OC(O)(CC(O)CC3OC3C=CC(=O)O1)CC(O)C2C(=O)O
Isomeric SMILES
C[C@@H]1C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@@H]3[C@H](O3)/C=C/C(=O)O1)O)O)O)C(=O)O)O[C@H]4[C@H]([C@H]([C@@H]([C@H](O4)C)O)N)O

Synonyms

  • pimaricin
  • Myprozine
  • Natacyn
  • Natamicina
  • Natamycine
  • Delvocid
  • Mycophyt
  • Pimaracin
  • Synogil
  • Natamycinum
  • Pimarizin
  • Pimafucin
  • Tennecetin
  • Delvolan
  • Pimaricine
  • Antibiotic A-5283
  • CL 12,625
  • INS NO.235
  • CL 12625
  • 16-(3-Amino-3,6-didesoxy-beta-D-mannopyranosyloxy)-5,6-epoxy-8,12,14-trihydroxy-26-methyl-2,10-dioxo-1-oxacyclohexacosa-3,17,19,21,23-pentaen-13-carbonsaeure
  • Delvopos
  • Natafucin
  • Natamycin(Pimaricin)
  • Tymasil
  • Tennecetin,
Show all 33 synonyms
  • Myprozine,
  • Natafucin,
  • Pimafucin,
  • Pimafugin,
  • Mycophyt,
  • Natacyn,
  • Synogil,
  • Pimaricin, Natamycin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Powderexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
665.73 g/molcalc.
Exact mass
665.3047 Dacalc.
LogP (octanol/water)
0.12calc.
Topological polar surface area
231 Ųcalc.
Hydrogen bond donors
7calc.
Hydrogen bond acceptors
13calc.
Rotatable bonds
3calc.
Heavy atoms
47calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.64calc.
Formal charge
0calc.
Stereocentres
14calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC2OC2CCCC2CCCC(CC(OC3CCCCO3)C=CC=CC=CC=CCCO1)O2

O=C1C=CC2OC2CCCC2CCCC(CC(OC3CCCCO3)C=CC=CC=CC=CCCO1)O2

4 rings, 36 atoms.

7 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Natamycin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 92 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

92 suppliers in 20 countries

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Natamycin price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Food additives.

Cosmetic ingredient, INCI name NATAMYCIN(antimicrobial, preservative)

Pharmacological actions

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Local
  • Antifungal Agents

Roles

  • additive
  • agrochemical
  • antifungal agent
  • antifungal agrochemical
  • antimicrobial agent
  • antimicrobial food preservative
  • apoptosis inducer
  • bacterial metabolite
  • food additive
  • food component
  • food preservative
  • fungicide
  • metabolite
  • ophthalmology drug
  • pesticide
  • pharmaceutical
  • physiological role
  • prokaryotic metabolite

Functional uses

  • Biocide
  • Preservative

Cosmetic functions

  • Antimicrobial
  • Preservative

Pharmacology

Natamycin is a Polyene Antimicrobial.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels
  • Food additive

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Natamycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Natamycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Natamycin, based on the data on this page

What is Natamycin?

Natamycin is a polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents.

What is the CAS number of Natamycin?

The CAS registry number of Natamycin is 7681-93-8. Other or deprecated CAS numbers: 52882-37-8.

What is the molecular formula and weight of Natamycin?

The molecular formula of Natamycin is C33H47NO13 and its molar mass is 665.73 g/mol.

What is Natamycin used for?

Use classes: Food additives.

Is Natamycin hazardous?

No GHS hazard classification for Natamycin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Natamycin?

Natamycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Natamycin?

CompoundList lists 92 suppliers of Natamycin in China, United States, India, Germany and 16 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Natamycin in India?

7 suppliers in India list Natamycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Natamycin?

Suppliers quote Natamycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Natamycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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