Niridazole
Also known as Nitrothiazole, Ambilhar, Nitrothiamidazol
Key facts
What buyers check first
- Appearance
- Yellow crystals from dimethylformamide/methanol
- Melting point
- 260 to 262 °C
- Solubility
- Insoluble in most organic solvents, soluble in dimethylformamide
- HS code
- 293410
- Category
- Antibiotics and anti-infectives

What is Niridazole?
Plain description, key identifiers and synonyms
Niridazole is a C-nitro compound and a member of 1,3-thiazoles.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 1-(5-nitro-1,3-thiazol-2-yl)imidazolidin-2-one
- CAS number
- 61-57-4 CAS number cross-checked
- EC number
- 200-512-6
- Molecular formula
- C6H6N4O3S
- UNII
- N116U8Y5QQ
- InChIKey
- RDXLYGJSWZYTFJ-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H6N4O3S/c11-5-7-1-2-9(5)6-8-3-4(14-6)10(12)13/h3H,1-2H2,(H,7,11)
- SMILES (canonical and isomeric)
- C1CN(C(=O)N1)C2=NC=C(S2)[N+](=O)[O-]
Synonyms
- Nitrothiazole
- Ambilhar
- Nitrothiamidazol
- Niridazolum
- Ciba 32644-Ba
- Niridazol
- 1-(5-nitro-1,3-thiazol-2-yl)imidazolidin-2-one
- BA 32644
- 1-(5-Nitro-2-thiazolyl)-2-imidazolidinone
- CIBA 32644BA
- niridazole-chlorethylcarboxamide
- BA, CIBA 32.644
- Nitrothiamidazole
- Nitrothiazol
- 2-Imidazolidinone, 1-(5-nitro-2-thiazolyl)-
- Ciba 32644
- Nitridazole
- BA 32644 Ciba
- NTOI
- 1-(5-Nitro-2-thiazolyl)-2-imidazolinone
- 1-(5-Nitro-2-thiazolyl)-2-oxotetrahydroimidazole
- 1-(5-Nitro-2-thiazolyl)imidazolidin-2-one
- 1-(5-Nitro-2-thiazolyl)-2-oxotetrahydroimidazol
- 1-(5-Nitrothiazol-2-yl)imidazolidin-2-one
- Niridazole (USAN/INN)
Show all 26 synonymsShow fewer synonyms
- 2-Imidazolidinone,1-(5-nitro-2-thiazolyl)-
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Yellow crystals from dimethylformamide/methanolexp.Measured value |
|---|---|
| Melting point | 260 to 262 °Cexp.Measured value |
| Solubility | Insoluble in most organic solvents, soluble in dimethylformamideexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 214.21 g/molcalc.Computed value |
|---|---|
| Exact mass | 214.0161 Dacalc.Computed value |
| LogP (octanol/water) | 0.58calc.Computed value |
| Topological polar surface area | 88.37 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 14calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.33calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C1NCCN1c1nccs1
2 rings, 11 atoms, the 1-(2-Thiazolyl)-2-imidazolidinone ring system.
22 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Niridazole suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
Post one free request and suppliers who make or trade Niridazole can send you quotes. Your contact details stay private until you accept a quote.
Niridazole price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Therapeutic category: Anthelmintic (Schistosoma).
Pharmacological actions
- Amebicides
- Schistosomicides
Roles
- anthelminthic drug
- antiinfective agent
- antiparasitic agent
- pharmaceutical
How it is made
Obtained by reaction of (2-amino-5-nitrothiazole) with 2- chloroethyl isocyanate followed by ring closure.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Niridazole is traded under.
Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the…
- Switzerland * partner reported36.4%
- Ireland28.8%
- China10.0%
- Canada33.4%
- United States14.4%
- Ireland13.1%
* Partner reported figures, a lower bound.
The HS code shown for Niridazole is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Niridazole, based on the data on this page
What is Niridazole?
What is the CAS number of Niridazole?
What is the molecular formula and weight of Niridazole?
What is Niridazole used for?
Is Niridazole hazardous?
What is the HS code of Niridazole?
Where can I buy Niridazole?
What is the price of Niridazole?
Guides for buyers
Practical guides that help when you source, ship or handle Niridazole
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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