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Murcko scaffold

1-(2-Thiazolyl)-2-imidazolidinone scaffold

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
23
With full pages
1
Scaffold SMILES

O=C1NCCN1c1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Thiazolyl)-2-imidazolidinone page
Murcko scaffold O=C1NCCN1c1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

Niridazole chemical structure, C6H6N4O3S, CAS 61-57-4
Niridazole
CAS 61-57-4C6H6N4O3S
5-Methyl-1-(5-nitro-2-thiazolyl)-2-imidazolidinone chemical structure, C7H8N4O3S, CAS 10560-74-4
5-Methyl-1-(5-nitro-2-thiazolyl)-2-imidazolidinone
CAS 10560-74-4C7H8N4O3S
2-Imidazolidinone, 3-nitroso-1-(5-nitro-2-thiazolyl)- chemical structure, C6H5N5O4S, CAS 34968-90-6
2-Imidazolidinone, 3-nitroso-1-(5-nitro-2-thiazolyl)-
CAS 34968-90-6C6H5N5O4S
4,5-Dihydroxy-1-(5-nitro-2-thiazolyl)-2-imidazolidinone chemical structure, C6H6N4O5S, CAS 72589-87-8
4,5-Dihydroxy-1-(5-nitro-2-thiazolyl)-2-imidazolidinone
CAS 72589-87-8C6H6N4O5S
5-Hydroxyniridazole chemical structure, C6H6N4O4S, CAS 72589-88-9
5-Hydroxyniridazole
CAS 72589-88-9C6H6N4O4S
2-Imidazolidinone, 1-((bis(2-methylpropyl)amino)methyl)-3-(5-nitro-2-thiazolyl)- chemical structure, C15H25N5O3S, CAS 76472-90-7
2-Imidazolidinone, 1-((bis(2-methylpropyl)amino)methyl)-3-(5-nitro-2-thiazolyl)-
CAS 76472-90-7C15H25N5O3S
1-(Dichloroacetyl)-3-(5-nitro-2-thiazolyl)-2-imidazolidinone chemical structure, C8H6Cl2N4O4S, CAS 92569-05-6
1-(Dichloroacetyl)-3-(5-nitro-2-thiazolyl)-2-imidazolidinone
CAS 92569-05-6C8H6Cl2N4O4S
1-(2-Thiazolyl)-2-imidazolidinone chemical structure, C6H7N3OS, CAS 10227-50-6
1-(2-Thiazolyl)-2-imidazolidinone
CAS 10227-50-6C6H7N3OS
4'-Methylniridazole chemical structure, C7H8N4O3S, CAS 10560-76-6
4'-Methylniridazole
CAS 10560-76-6C7H8N4O3S
2-Imidazolidinone, 1-acetyl-3-(5-nitro-2-thiazolyl)- chemical structure, C8H8N4O4S, CAS 6616-82-6
2-Imidazolidinone, 1-acetyl-3-(5-nitro-2-thiazolyl)-
CAS 6616-82-6C8H8N4O4S
2-Imidazolidinone, 1-(5-methyl-2-thiazolyl)- chemical structure, C7H9N3OS, CAS 572922-57-7
2-Imidazolidinone, 1-(5-methyl-2-thiazolyl)-
CAS 572922-57-7C7H9N3OS
1-(4-Methylthiazol-2-yl)imidazolidin-2-one chemical structure, C7H9N3OS, CAS 519143-32-9
1-(4-Methylthiazol-2-yl)imidazolidin-2-one
CAS 519143-32-9C7H9N3OS
2-[2-(2-Oxoimidazolidin-1-yl)-1,3-thiazol-4-yl]acetic acid chemical structure, C8H9N3O3S, CAS 1114822-84-2
2-[2-(2-Oxoimidazolidin-1-yl)-1,3-thiazol-4-yl]acetic acid
CAS 1114822-84-2C8H9N3O3S
4-Hydroxyniridazole chemical structure, C6H6N4O4S, CAS 72589-86-7
4-Hydroxyniridazole
CAS 72589-86-7C6H6N4O4S
1-(5-Acetyl-4-methylthiazol-2-yl)imidazolidin-2-one chemical structure, C9H11N3O2S, CAS 1072805-54-9
1-(5-Acetyl-4-methylthiazol-2-yl)imidazolidin-2-one
CAS 1072805-54-9C9H11N3O2S
Ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate chemical structure, C10H13N3O3S, CAS 1072806-73-5
Ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate
CAS 1072806-73-5C10H13N3O3S
Methyl 2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate chemical structure, C8H9N3O3S, CAS 1072806-52-0
Methyl 2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate
CAS 1072806-52-0C8H9N3O3S
1-Methyl-3-(5-nitro-1,3-thiazol-2-yl)imidazolidin-2-one chemical structure, C7H8N4O3S, CAS 14746-93-1
1-Methyl-3-(5-nitro-1,3-thiazol-2-yl)imidazolidin-2-one
CAS 14746-93-1C7H8N4O3S
3-(5-Bromo-1,3-thiazol-2-yl)-4-hydroxy-1-methylimidazolidin-2-one chemical structure, C7H8BrN3O2S, CAS 64588-77-8
3-(5-Bromo-1,3-thiazol-2-yl)-4-hydroxy-1-methylimidazolidin-2-one
CAS 64588-77-8C7H8BrN3O2S
3-(5-Fluoro-2-thiazolyl)-4-hydroxy-1-(2-propen-1-yl)-2-imidazolidinone chemical structure, C9H10FN3O2S, CAS 64588-83-6
3-(5-Fluoro-2-thiazolyl)-4-hydroxy-1-(2-propen-1-yl)-2-imidazolidinone
CAS 64588-83-6C9H10FN3O2S
1-(5-Chloro-1,3-thiazol-2-yl)imidazolidin-2-one chemical structure, C6H6ClN3OS, CAS 13109-95-0
1-(5-Chloro-1,3-thiazol-2-yl)imidazolidin-2-one
CAS 13109-95-0C6H6ClN3OS
1-Nitro-3-(2-thiazolyl)-2-imidazolidinone chemical structure, C6H6N4O3S, CAS 10227-53-9
1-Nitro-3-(2-thiazolyl)-2-imidazolidinone
CAS 10227-53-9C6H6N4O3S
1-Nitro-3-(5-nitro-2-thiazolyl)-2-imidazolidinone chemical structure, C6H5N5O5S, CAS 10389-66-9
1-Nitro-3-(5-nitro-2-thiazolyl)-2-imidazolidinone
CAS 10389-66-9C6H5N5O5S