CompoundList
Sign in
Analgesics and anti-inflammatories

Oxaprozin

Also known as Daypro, 3-(4,5-Diphenyloxazol-2-yl)propanoic acid, Alvo

CAS 21256-18-8Formula C18H15NO3Molar mass 293.32 g/molEC 244-296-1
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 84 suppliers listed Drug substance
Get quotes Compare 84 suppliers
Oxaprozin chemical structure, C18H15NO3, CAS 21256-18-8
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from methanol
Melting point
160.5 to 161.5
Solubility
Slightly soluble in alcohol. Insoluble in water
HS code
293499
Category
Analgesics and anti-inflammatories
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Oxaprozin?

Plain description, key identifiers and synonyms

Oxaprozin is a monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug and an analgesic. It is a monocarboxylic acid and a member of 1,3-oxazoles. It is functionally related to a propionic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
CAS number
21256-18-8 CAS number cross-checked
EC number
244-296-1
Molecular formula
C18H15NO3
UNII
MHJ80W9LRB
MDL number
MFCD00215977
InChIKey
OFPXSFXSNFPTHF-UHFFFAOYSA-N
InChI
InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)
SMILES (canonical and isomeric)
C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3

Synonyms

  • Daypro
  • 3-(4,5-Diphenyloxazol-2-yl)propanoic acid
  • Alvo
  • Oxaprozine
  • Oxaprozinum
  • Deflam
  • Oxaprozina
  • 4,5-Diphenyl-2-oxazolepropanoic acid
  • 4,5-Diphenyl-2-oxazolepropionic acid
  • WY-21,743
  • 2-Oxazolepropanoic acid, 4,5-diphenyl-
  • Duraprox
  • WY 21743
  • Coxanto
  • beta-(4,5-Diphenyloxazol-2-yl)propionic acid
  • 3-(diphenyl-1,3-oxazol-2-yl)propanoic acid
  • Apo Oxaprozin
  • Rhoxal oxaprozin
  • Oxaprozin (USAN:USP:INN:BAN:JAN)
  • 4,5 Diphenyl 2 oxazolepropionic Acid
  • Wy 21,743
  • 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
  • Oxaprozinum, Wy21743
  • 3-(4,5-Diphenyl-2-oxazolyl)propenoic acid
  • Voir
Show all 33 synonyms
  • 2-Oxazolepropionic acid, 4,5-diphenyl-
  • Danoprox
  • Dayrun
  • Actirin
  • Xopane
  • Daypro (TN)
  • oxaprosin
  • Durapro

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from methanolexp.
Melting point
160.5 to 161.5exp.
Solubility
Slightly soluble in alcohol. Insoluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
293.32 g/molcalc.
Exact mass
293.1052 Dacalc.
LogP (octanol/water)
4.03calc.
Topological polar surface area
63.33 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
5calc.
Heavy atoms
22calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.11calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(-c2ncoc2-c2ccccc2)cc1

c1ccc(-c2ncoc2-c2ccccc2)cc1

3 rings, 17 atoms, the 4,5-Diphenyloxazole ring system.

145 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H411Toxic to aquatic life with long lasting effects.
  • H412Harmful to aquatic life with long lasting effects.
  • H413May cause long lasting harmful effects to aquatic life.
Precautionary statements (15)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Oxaprozin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 84 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

84 suppliers in 16 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Oxaprozin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Anti-inflammatory.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase Inhibitors

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Pharmacology

Oxaprozin is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor.

How it is made

Preparation: FR 2001036 (1969 Inst Farm Serano), ... K. Brown GB 1206403 and US 3578671 (1970, 1971 to Wyeth)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Oxaprozin is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Oxaprozin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Oxaprozin, based on the data on this page

What is Oxaprozin?

Oxaprozin is a monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis.

What is the CAS number of Oxaprozin?

The CAS registry number of Oxaprozin is 21256-18-8.

What is the molecular formula and weight of Oxaprozin?

The molecular formula of Oxaprozin is C18H15NO3 and its molar mass is 293.32 g/mol.

What is Oxaprozin used for?

Therapeutic category: Anti-inflammatory. Use classes: Pharmaceuticals.

Is Oxaprozin hazardous?

Oxaprozin carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Oxaprozin?

Oxaprozin is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Oxaprozin?

CompoundList lists 84 suppliers of Oxaprozin in China, United States, United Kingdom, Germany and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Oxaprozin in India?

2 suppliers in India list Oxaprozin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Oxaprozin?

Suppliers quote Oxaprozin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Oxaprozin

Get quotes for Oxaprozin

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Oxaprozin
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Oxaprozin with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/oxaprozin-21256-18-8" title="Oxaprozin structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Analgesics and anti-inflammatories or HS code 293499

84 suppliers
Free quotes, contact stays private
Get quotes