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Antibiotics and anti-infectives

Oxolinic acid

Also known as Utibid, Prodoxal, Ossian

CAS 14698-29-4Formula C13H11NO5Molar mass 261.23 g/molEC 238-750-8
GHS signal word: Warning. Pictograms: Harmful or irritant 87 suppliers listed Drug substance
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Oxolinic acid chemical structure, C13H11NO5, CAS 14698-29-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
14698-29-4
Formula
C13H11NO5
Appearance
Crystals from dimethylformamide
Melting point
314 to 316
HS code
293499
Category
Antibiotics and anti-infectives
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Oxolinic acid?

Plain description, key identifiers and synonyms

Oxolinic acid is a quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. It has a role as an enzyme inhibitor, an antimicrobial agent, an antiinfective agent, an antifungal agent and an antibacterial drug. It is a quinolinemonocarboxylic acid, an organic heterotricyclic compound, an aromatic carboxylic acid, an oxacycle and a quinolone antibiotic. It is a conjugate acid of an oxolinate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
CAS number
14698-29-4 CAS number cross-checked
EC number
238-750-8
Molecular formula
C13H11NO5
UNII
L0A22B22FT
MDL number
MFCD00056775
InChIKey
KYGZCKSPAKDVKC-UHFFFAOYSA-N
InChI
InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)
SMILES (canonical and isomeric)
CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O

Synonyms

  • Utibid
  • Prodoxal
  • Ossian
  • Pietil
  • Acido oxolinico
  • Acide oxolinique
  • Acidum oxolinicum
  • Aqualinic
  • 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
  • 5-Ethyl-8-oxo-5,8-dihydro[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
  • 1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid
  • 1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid
  • 5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid
  • 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-
  • 1,3-Dioxolo[4,5-g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo-
  • 5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
  • Acid, Oxolinic
  • 5-ethyl-8-oxo-(1,3)dioxolo(4,5-g)quinoline-7-carboxylic acid
  • 5-ethyl-8-oxo-5,8-dihydro(1,3)dioxolo(4,5-g)quinoline-7-carboxylic acid
  • Oxolinate, Sodium
  • 5-Ethyl-8-oxo-5,8-dihydro (1,3) dioxolo (4,5-g) quinoline-7-carboxylic acid
  • Nidantin
  • Dioxacin
  • Emyrenil
  • Prodoxol
Show all 38 synonyms
  • Starner
  • Uroxol
  • Gramurin
  • Oksaren
  • Oxolinic
  • Ultibid
  • Uritrate
  • Urotrate
  • Oxoboi
  • Uro-alvar
  • 5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
  • Oxolinic acid impurity B
  • Cistopax

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from dimethylformamideexp.
Melting point
314 to 316exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
261.23 g/molcalc.
Exact mass
261.0637 Dacalc.
LogP (octanol/water)
1.45calc.
Topological polar surface area
77.76 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
19calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.23calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc[nH]c2cc3c(cc12)OCO3

O=c1cc[nH]c2cc3c(cc12)OCO3

3 rings, 14 atoms, the 1,3-Dioxolo[4,5-g]quinolin-8(5H)-one ring system.

39 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Oxolinic acid suppliers

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All 87 suppliers
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Where suppliers are based

87 suppliers in 13 countries

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Oxolinic acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Urinary
  • Topoisomerase II Inhibitors

Roles

  • antibacterial agent
  • antibacterial drug
  • antifungal agent
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • enzyme inhibitor
  • pharmaceutical

Pharmacology

Quinolone Antibiotic is the basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new derivative compounds with broad antibacterial activity. Both DNA gyrase and topoisomerase IV are targets of quinolones.

How it is made

Kaminsky, meltzer, us pat 3,287,458 (1966 to warner-lambert) eidem, j med chem, 11, 160 (1968).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Oxolinic acid is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Oxolinic acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Oxolinic acid, based on the data on this page

What is Oxolinic acid?

Oxolinic acid is a quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions.

What is the CAS number of Oxolinic acid?

The CAS registry number of Oxolinic acid is 14698-29-4.

What is the molecular formula and weight of Oxolinic acid?

The molecular formula of Oxolinic acid is C13H11NO5 and its molar mass is 261.23 g/mol.

What is Oxolinic acid used for?

Known uses and roles of Oxolinic acid include antibacterials and antibiotics in pharmaceuticals, anticancer drugs in pharmaceuticals, antibacterial agent, antibacterial drug, antifungal agent and 8 more.

Is Oxolinic acid hazardous?

Oxolinic acid carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Oxolinic acid?

Oxolinic acid is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Oxolinic acid?

CompoundList lists 87 suppliers of Oxolinic acid in United States, China, Germany, United Kingdom and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Oxolinic acid?

Suppliers quote Oxolinic acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Oxolinic acid

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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