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Murcko scaffold

1,3-Dioxolo[4,5-g]quinolin-8(5H)-one scaffold

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
40
With full pages
9
Scaffold SMILES

O=c1cc[nH]c2cc3c(cc12)OCO3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3-Dioxolo[4,5-g]quinolin-8(5H)-one page
Murcko scaffold O=c1cc[nH]c2cc3c(cc12)OCO3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

Oxolinic acid chemical structure, C13H11NO5, CAS 14698-29-4
Oxolinic acid
CAS 14698-29-4C13H11NO5
1,3-Dioxolo(4,5-g)quinolin-8(5H)-one, 7-acetyl-5-ethyl- chemical structure, C14H13NO4, CAS 34841-20-8
1,3-Dioxolo(4,5-g)quinolin-8(5H)-one, 7-acetyl-5-ethyl-
CAS 34841-20-8C14H13NO4
Miloxacin chemical structure, C12H9NO6, CAS 37065-29-5
Miloxacin
CAS 37065-29-5C12H9NO6
Ethyl 8-hydroxy-(1,3)dioxolo(4,5-g)quinoline-7-carboxylate chemical structure, C13H11NO5, CAS 14205-65-3
Ethyl 8-hydroxy-(1,3)dioxolo(4,5-g)quinoline-7-carboxylate
CAS 14205-65-3C13H11NO5
EN 272 chemical structure, C12H7F2NO5, CAS 64621-47-2
EN 272
CAS 64621-47-2C12H7F2NO5
1,3-Dioxolo(4,5-g)quinolin-8(5H)-one, 7-acetyl- chemical structure, C12H9NO4, CAS 34841-19-5
1,3-Dioxolo(4,5-g)quinolin-8(5H)-one, 7-acetyl-
CAS 34841-19-5C12H9NO4
5,8-Dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid chemical structure, C11H7NO5, CAS 19746-58-8
5,8-Dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid
CAS 19746-58-8C11H7NO5
1,3-Dioxolo(4,5-g)quinoline-7-carbonyl chloride, 5-ethyl-5,8-dihydro-8-oxo- chemical structure, C13H10ClNO4, CAS 19658-59-4
1,3-Dioxolo(4,5-g)quinoline-7-carbonyl chloride, 5-ethyl-5,8-dihydro-8-oxo-
CAS 19658-59-4C13H10ClNO4
6-Methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one chemical structure, C11H9NO3, CAS 50593-64-1
6-Methyl-2H-[1,3]dioxolo[4,5-g]quinolin-8(5H)-one
CAS 50593-64-1C11H9NO3
1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo- chemical structure, C13H12N2O5, CAS 51624-54-5
1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-
CAS 51624-54-5C13H12N2O5
1,3-Dioxolo(4,5-g)quinoline-7-carbonitrile, 5,8-dihydro-5-ethyl-8-oxo- chemical structure, C13H10N2O3, CAS 57147-33-8
1,3-Dioxolo(4,5-g)quinoline-7-carbonitrile, 5,8-dihydro-5-ethyl-8-oxo-
CAS 57147-33-8C13H10N2O3
Glycine, N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)-, ethyl ester chemical structure, C17H18N2O6, CAS 110261-15-9
Glycine, N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)-, ethyl ester
CAS 110261-15-9C17H18N2O6
Butanoic acid, 2-(((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)amino)- chemical structure, C17H18N2O6, CAS 110261-16-0
Butanoic acid, 2-(((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)amino)-
CAS 110261-16-0C17H18N2O6
1,3-Dioxolo(4,5-g)quinoline-7-carboxamide, 5,8-dihydro-5-ethyl-N-(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)-8-oxo-, hemihydrate chemical structure, C17H20N2O7, CAS 136281-52-2
1,3-Dioxolo(4,5-g)quinoline-7-carboxamide, 5,8-dihydro-5-ethyl-N-(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)-8-oxo-, hemihydrate
CAS 136281-52-2C17H20N2O7
Ethyl 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxolo[4,5-g]quinoline-7-carboxylate (Oxolinic Acid Ethyl Ester) chemical structure, C15H15NO5, CAS 16172-03-5
Ethyl 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxolo[4,5-g]quinoline-7-carboxylate (Oxolinic Acid Ethyl Ester)
CAS 16172-03-5C15H15NO5
L-Alanine, N-((5,8-dihydro-5-ethyl-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)- chemical structure, C16H16N2O6, CAS 79721-05-4
L-Alanine, N-((5,8-dihydro-5-ethyl-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)-
CAS 79721-05-4C16H16N2O6
Glycine, N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)- chemical structure, C15H14N2O6, CAS 97515-38-3
Glycine, N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)-
CAS 97515-38-3C15H14N2O6
(S)-2-(5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxamido)-3-methylbutanoic acid chemical structure, C18H20N2O6, CAS 956626-62-3
(S)-2-(5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxamido)-3-methylbutanoic acid
CAS 956626-62-3C18H20N2O6
(S)-2-(5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxamido)-4-methylpentanoic acid chemical structure, C19H22N2O6, CAS 105329-10-0
(S)-2-(5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxamido)-4-methylpentanoic acid
CAS 105329-10-0C19H22N2O6
beta-Alanine, N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)- chemical structure, C16H16N2O6, CAS 104571-64-4
beta-Alanine, N-((5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)-
CAS 104571-64-4C16H16N2O6
6-(((5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)amino)hexanoic acid chemical structure, C19H22N2O6, CAS 104571-66-6
6-(((5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinolin-7-yl)carbonyl)amino)hexanoic acid
CAS 104571-66-6C19H22N2O6
8-Oxo-5,8-dihydro-2H-[1,3]dioxolo[4,5-g]quinoline-6,7-dicarboxylic acid chemical structure, C12H7NO7, CAS 61707-78-6
8-Oxo-5,8-dihydro-2H-[1,3]dioxolo[4,5-g]quinoline-6,7-dicarboxylic acid
CAS 61707-78-6C12H7NO7
5,8-Dihydro-8-oxo-5-(2-propen-1-yloxy)-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid chemical structure, C14H11NO6, CAS 37065-30-8
5,8-Dihydro-8-oxo-5-(2-propen-1-yloxy)-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid
CAS 37065-30-8C14H11NO6
8-Hydroxy-6-methyl-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid chemical structure, C12H9NO5, CAS 50435-15-9
8-Hydroxy-6-methyl-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
CAS 50435-15-9C12H9NO5