p-Aminoacetophenone
Also known as 4'-Aminoacetophenone, 1-(4-Aminophenyl)ethanone, 4-Aminoacetophenone
Key facts
What buyers check first
- Appearance
- Yellow monoclinic prisms from alcohol
- Melting point
- 106 ยฐC
- Boiling point
- 294 ยฐC
- Solubility
- In water, 3.35 ร 10โบยณ mg/L at 37 ยฐC
- HS code
- 292239
- Category
- Impurities and reference standards

What is p-Aminoacetophenone?
Plain description, key identifiers and synonyms
p-Aminoacetophenone is a chemical substance with the molecular formula C8H9NO and a molar mass of 135.17 g/mol. Its CAS registry number is 99-92-3. The IUPAC name is 1-(4-aminophenyl)ethanone.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 1-(4-aminophenyl)ethanone
- CAS number
- 99-92-3 CAS number cross-checked
- EC number
- 202-801-2
- Molecular formula
- C8H9NO
- UNII
- 1S58KH902I
- MDL number
- MFCD00007896
- InChIKey
- GPRYKVSEZCQIHD-UHFFFAOYSA-N
- InChI
- InChI=1S/C8H9NO/c1-6(10)7-2-4-8(9)5-3-7/h2-5H,9H2,1H3
- SMILES (canonical and isomeric)
- CC(=O)C1=CC=C(C=C1)N
Synonyms
- 4'-Aminoacetophenone
- 1-(4-Aminophenyl)ethanone
- 4-Aminoacetophenone
- 4-Acetylaniline
- p-Acetylaniline
- Ethanone, 1-(4-aminophenyl)-
- p-Aminoacetylbenzene
- Acetophenone, p-amino-
- USAF EK-631
- Acetophenone, 4-amino-
- para-aminoacetophenone
- 1-(4-Aminophenyl)Ethan-1-One
- Acetophenone, 4'-amino-
- Clenbuterol EP Impurity D
- p-Aminoacetofenonu
- 1-acetyl-4-aminobenzene
- 1-(4-Aminophenyl)-ethanone
- 4'-aminoacetophenon
- p-amino acetophenone
- 4-Acetylaniline, p-Aminoacetophenone, p-Aminoacetylbenzene
- 4-acetylanilin
- p-aminoacetophenon
- p-amino-acetophenone
- 4-acetyl phenylamine
- 4-amino acetophenone
Show all 34 synonymsShow fewer synonyms
- aniline, 4-acetyl-
- Clenbuterol Impurity D
- para-amino acetophenone
- 4'-Amino acetophenone
- 4-Amino-acetophenon
- 1-(4-aminophenyl) ethanone
- 4'-Aminoacetophenone, 99%
- 4-14-00-00100 (Beilstein Handbook Reference)
- 1-(4-amino-phenyl)-ethanone
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Yellow monoclinic prisms from alcoholexp.Measured value |
|---|---|
| Odour | Pleasant, characteristic odorexp.Measured value |
| Melting point | 106 ยฐCexp.Measured value |
| Boiling point | 294 ยฐCexp.Measured value |
| Solubility | In water, 3.35 ร 10โบยณ mg/L at 37 ยฐCexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 135.17 g/molcalc.Computed value |
|---|---|
| Exact mass | 135.0684 Dacalc.Computed value |
| LogP (octanol/water) | 1.47calc.Computed value |
| Topological polar surface area | 43.09 ร
ยฒcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 2calc.Computed value |
| Rotatable bonds | 1calc.Computed value |
| Heavy atoms | 10calc.Computed value |
| Rings | 1calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.13calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H302Harmful if swallowed.
- H312Harmful in contact with skin.
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H332Harmful if inhaled.
- H335May cause respiratory irritation.
Precautionary statements (20)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P270Do not eat, drink or smoke when using this product.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P301 + P317If swallowed: Get medical help.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317Get medical help.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P330Rinse mouth.
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidp-Aminoacetophenone suppliers
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Where suppliers are based
33 suppliers in 10 countries
- China13
- India4
- United States4
- Canada2
- Hong Kong2
- Czech Republic1
- and 4 more countries
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p-Aminoacetophenone price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Laboratory reagent.
For treating intoxication with cyanogenic toxic substances.
Chemical intermediate for flavaniline (basic dye), acetohexamide, and an oral hypoglycemic drug.
How it is made
Transfer hydrogenation of p-nitroacetophenone with palladium catalyst and cyclohexene hydrogen donor
Regulatory status
Inventories, regulations and trade controls that list this substance
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code p-Aminoacetophenone is traded under.
Amino-aldehydes, amino-ketones and amino-quinones, other than those containing more thanโฆ
- Germany17.3%
- United States13.8%
- India * partner reported9.9%
* Partner reported figures, a lower bound.
The HS code shown for p-Aminoacetophenone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about p-Aminoacetophenone, based on the data on this page
What is p-Aminoacetophenone?
What is the CAS number of p-Aminoacetophenone?
What is the molecular formula and weight of p-Aminoacetophenone?
What is p-Aminoacetophenone used for?
Is p-Aminoacetophenone hazardous?
What is the HS code of p-Aminoacetophenone?
Where can I buy p-Aminoacetophenone?
Where can I buy p-Aminoacetophenone in India?
What is the price of p-Aminoacetophenone?
Guides for buyers
Practical guides that help when you source, ship or handle p-Aminoacetophenone
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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