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Paraoxon chemical structure, C10H14NO6P, CAS 311-45-5
2D chemical structure

Key facts

What buyers check first

Appearance
Oily liquid
Boiling point
168.9 to 170
Density
1.2683 at 25 °C/4 °C
Solubility
In water, 3,640 mg/l at 20 °C.
HS code
291990
Category
Insecticides and acaricides
UN number
UN 3018
Illustrative photo, 200 litre steel drums of liquid in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Paraoxon?

Plain description, key identifiers and synonyms

Paraoxon is an aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and a mouse metabolite. It is an organophosphate insecticide and an aryl dialkyl phosphate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
diethyl (4-nitrophenyl) phosphate
CAS number
311-45-5 CAS number cross-checked
EC number
206-221-0
Molecular formula
C10H14NO6P
UNII
Q9CX8P80JW
MDL number
MFCD00007316
InChIKey
WYMSBXTXOHUIGT-UHFFFAOYSA-N
InChI
InChI=1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
SMILES (canonical and isomeric)
CCOP(=O)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-]

Synonyms

  • Phosphacol
  • Diethyl paraoxon
  • Miotisal
  • Ethyl paraoxon
  • Diethyl 4-nitrophenyl phosphate
  • Mintacol
  • Diethyl p-nitrophenyl phosphate
  • Phosphachole
  • Fosfakol
  • Oxyparathion
  • Chinorto
  • Phosphakol
  • Eticol
  • Chinorta
  • Paraoxone
  • Soluglaucit
  • Mintaco
  • Paroxan
  • Miotisal A
  • Phosphoric acid, diethyl 4-nitrophenyl ester
  • Ester 25
  • Diethylparaoxon
  • Soluglacit
  • Pestox 101
  • p-Nitrophenyl diethyl phosphate
Show all 39 synonyms
  • E 600 (pesticide)
  • Mintisal
  • diethyl (4-nitrophenyl) phosphate
  • O,O-Diethyl O-p-nitrophenyl phosphate
  • Phosphoric acid diethyl 4-nitrophenyl ester
  • Diethyl-p-nitrophenyl phosphate
  • Ts 219
  • ENT 16,087
  • O,O-Dietyl-O-p-nitrofenylfosfat
  • HC 2072
  • Ethyl p-nitrophenyl ethylphosphate
  • p-Nitrophenyl diethylphosphate
  • Phosphoric acid, diethyl p-nitrophenyl ester
  • Diethyl-p-nitrofenyl ester kyseliny fosforecne

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Oily liquidexp.
Odour
SLIGHT ODORexp.
Boiling point
168.9 to 170exp.
Density
1.2683 at 25 °C/4 °Cexp.
Solubility
In water, 3,640 mg/l at 20 °C.exp.
Vapour pressure
1.1 × 10⁻⁶ mm Hg at 25 °C.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
275.20 g/molcalc.
Exact mass
275.0559 Dacalc.
LogP (octanol/water)
3.15calc.
Topological polar surface area
87.9 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
7calc.
Heavy atoms
18calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H330Fatal if inhaled.
  • H400Very toxic to aquatic life.
Precautionary statements (20)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3018

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Paraoxon suppliers

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  • United States, WoburnUnclaimed profile
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  • China, ChangzhouUnclaimed profile
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  • Germany, LorrachUnclaimed profile
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  • China, NanjingUnclaimed profile
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  • United States, AustinUnclaimed profile
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  • China, ShangHaiUnclaimed profile
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Where suppliers are based

31 suppliers in 10 countries

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Paraoxon price

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Uses and applications

What the substance is used for, by industry and function

Action: Insecticide. Not registered for use in the U.S.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Cholinesterase Inhibitors
  • Insecticides

Roles

  • animal metabolite
  • antiglaucoma drug
  • enzyme inhibitor
  • eukaryotic metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • ophthalmology drug
  • pharmaceutical

Pharmacology

Paraoxon is a synthetic aryl dialkyl phosphate compound and organophosphate acetylcholinesterase inhibitor that is the active metabolite of the insecticide parathion and is used as a pesticide. It is characterized as a reddish-yellow oily liquid with a faint fruity odor, and exposure occurs by inhalation, ingestion, or contact.

How it is made

Prepared by action of diethyl chlorophosphate on sodium para-nitrophenolate or by nitration of diethyl phenyl phosphate: schrader, bios final rept 714: 52 (1947), angew chem 62: 471 (1950), swiss patent number 257,649 (1949), fagerlind et al, svensk farm tid 56, 303, ca 46, 9259.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Diethyl 4-nitrophenyl phosphate (Paraoxon - ISO), Ref no: 170, Annex ref: II/170

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Paraoxon is traded under.

HS 2919.90Indicative HS code

Phosphoric, and their salts, including lactophosphates, their halogenated, sulphonated, nitrated…

World exports in 2024
$940M
−0.7% vs 2023, imports $863M
2019 to 2024
Top exporters
  1. China55.6%
  2. Germany10.6%
  3. Italy6.2%
Top importers
  1. United States15.8%
  2. South Korea10.1%
  3. Germany6.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Paraoxon is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Paraoxon, based on the data on this page

What is Paraoxon?

Paraoxon is an aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor and a mouse metabolite. It is an organophosphate insecticide and an aryl dialkyl phosphate.

What is the CAS number of Paraoxon?

The CAS registry number of Paraoxon is 311-45-5.

What is the molecular formula and weight of Paraoxon?

The molecular formula of Paraoxon is C10H14NO6P and its molar mass is 275.20 g/mol.

What is Paraoxon used for?

Action: Insecticide. Not registered for use in the U.S. Use classes: Pharmaceuticals.

Is Paraoxon hazardous?

Paraoxon carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Paraoxon?

Paraoxon is usually classified under HS code 291990 (Phosphoric esters and their salts, including lactophosphates, their halogenated…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Paraoxon?

CompoundList lists 31 suppliers of Paraoxon in United States, China, Germany, Spain and 6 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Paraoxon?

Suppliers quote Paraoxon on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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