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Cardiovascular and metabolic drugs

Pemafibrate

Also known as (R)-K-13675, pemafibrato, K-13675, (R)-

CAS 848259-27-8Formula C28H30N2O6Molar mass 490.56 g/mol
14 suppliers listed
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Pemafibrate chemical structure, C28H30N2O6, CAS 848259-27-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
848259-27-8
Formula
C28H30N2O6
Molar mass
490.56 g/mol
HS code
293499
Category
Cardiovascular and metabolic drugs

What is Pemafibrate?

Plain description, key identifiers and synonyms

Pemafibrate is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-amine in which the amino hydrogens are replaced by 3-[(1R)-1-carboxypropoxy]benzyl and 3-(4-methoxyphenoxy)propyl groups. It is a selective peroxisome proliferator-activated receptor (PPAR)-alpha agonist that is used for the treatment of hyperlipidaemia. It has a role as an antilipemic drug, a hepatoprotective agent and a PPARalpha agonist. It is a monocarboxylic acid, an aromatic amine, a tertiary amino compound, a member of 1,3-benzoxazoles and a member of methoxybenzenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
CAS number
848259-27-8 CAS number cross-checked
Molecular formula
C28H30N2O6
UNII
17VGG92R23
MDL number
MFCD30533427
InChIKey
ZHKNLJLMDFQVHJ-RUZDIDTESA-N
InChI
InChI=1S/C28H30N2O6/c1-3-25(27(31)32)35-23-9-6-8-20(18-23)19-30(28-29-24-10-4-5-11-26(24)36-28)16-7-17-34-22-14-12-21(33-2)13-15-22/h4-6,8-15,18,25H,3,7,16-17,19H2,1-2H3,(H,31,32)/t25-/m1/s1
Canonical SMILES
CCC(Oc1cccc(CN(CCCOc2ccc(OC)cc2)c2nc3ccccc3o2)c1)C(=O)O
Isomeric SMILES
CC[C@H](C(=O)O)OC1=CC=CC(=C1)CN(CCCOC2=CC=C(C=C2)OC)C3=NC4=CC=CC=C4O3

Synonyms

  • (R)-K-13675
  • pemafibrato
  • K-13675, (R)-
  • pemafibratum
  • (2R)-2-(3-(((1,3-benzoxazol-2-yl)(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid
  • (2R)-2-[3-({(1,3-Benzoxazol-2-yl)[3-(4-methoxyphenoxy)propyl]amino}methyl)phenoxy]butanoic acid
  • (2R)-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
  • (R)-2-(3-((benzo[d]oxazol-2-yl(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid
  • (R)-K 13675
  • Pemafibrate (JAN)
  • parmodia
  • (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
  • Pemafibrate?
  • Parmodia (TN)
  • (R)-2-(3-((N-(Benzoxazol-2-yl)-N-(3-(4-methoxyphenoxy)propyl)amino)methyl)phenoxy)butanoic acid
  • (R)-2-[3-[(Benzo[d]oxazol-2-yl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic Acid
  • (R)-2-[3-[[N-(benzoxazol-2-yl)-N-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
  • Pemafibrate (Standard)
  • Pemafibrate [(R)-K-13675
  • (2R)-2-[3-({1,3-benzoxazol-2-yl[3-(4-methoxyphenoxy)propyl]amino}methyl)phenoxy]butanoic acid
  • K-877, (R)-K 13675, CS-2768
  • (2 R)-2-[3-[[2-benzoxazolyl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]-Butanoic acid
  • (2R)-2-[3-[[2-benzoxazolyl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid
  • (R)-2-[3-[N-(benzoxazol-2-yl)-N-(3-(4-methoxyphenoxy)propyl)aminomethyl]phenoxy]butyric acid
  • Butanoic acid, 2-[3-[[2-benzoxazolyl[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]-, (2R)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
490.56 g/molcalc.
Exact mass
490.2104 Dacalc.
LogP (octanol/water)
5.55calc.
Topological polar surface area
94.26 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
13calc.
Heavy atoms
36calc.
Rings
4calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.29calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)cc1

c1ccc(CN(CCCOc2ccccc2)c2nc3ccccc3o2)cc1

4 rings, 27 atoms.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Pemafibrate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 14 suppliers
14 of 14 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

14 suppliers in 2 countries

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Pemafibrate price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • PPAR modulator
  • PPARalpha agonist
  • agonist
  • antilipemic drug
  • cardiovascular drug
  • hepatoprotective agent
  • pharmaceutical
  • protective agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pemafibrate is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Pemafibrate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pemafibrate, based on the data on this page

What is Pemafibrate?

Pemafibrate is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-amine in which the amino hydrogens are replaced by 3-[(1R)-1-carboxypropoxy]benzyl and 3-(4-methoxyphenoxy)propyl groups.

What is the CAS number of Pemafibrate?

The CAS registry number of Pemafibrate is 848259-27-8.

What is the molecular formula and weight of Pemafibrate?

The molecular formula of Pemafibrate is C28H30N2O6 and its molar mass is 490.56 g/mol.

What is Pemafibrate used for?

Known uses and roles of Pemafibrate include cardiovascular drugs in pharmaceuticals, ppar modulator, pparalpha agonist, agonist, antilipemic drug and 4 more.

Is Pemafibrate hazardous?

No GHS hazard classification for Pemafibrate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Pemafibrate?

Pemafibrate is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pemafibrate?

CompoundList lists 14 suppliers of Pemafibrate in China and Bangladesh. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Pemafibrate?

Suppliers quote Pemafibrate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pemafibrate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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