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Other active pharmaceutical ingredients

Perfluoropropane

Also known as Perflutren, Octafluoropropane, 1,1,1,2,2,3,3,3-Octafluoropropane

CAS 76-19-7Formula C3F8Molar mass 188.02 g/molEC 200-941-9
GHS signal word: Warning. Pictograms: Gas under pressure 58 suppliers listed Drug substance
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Perfluoropropane chemical structure, C3F8, CAS 76-19-7
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless, nonflammable gas
Melting point
-147.6 °C
Boiling point
-36.7 °C
Density
1.352 at 20 °C (liquid)
Solubility
In water, 5.7 mg/L at 15 °C
HS code
290349
Category
Other active pharmaceutical ingredients
UN number
UN 2424
Illustrative photo, a gas cylinder on a trolley on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Perfluoropropane?

Plain description, key identifiers and synonyms

Octafluoropropane is a fluorocarbon that is propane in which all of the hydrogens have been replaced by fluorines. It is a fluoroalkane and a fluorocarbon. It derives from a hydride of a propane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,1,1,2,2,3,3,3-octafluoropropane
CAS number
76-19-7 CAS number cross-checked
EC number
200-941-9
Molecular formula
C3F8
UNII
CK0N3WH0SR
MDL number
MFCD00039239
INCI name
PERFLUOROPROPANE
InChIKey
QYSGYZVSCZSLHT-UHFFFAOYSA-N
InChI
InChI=1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
SMILES (canonical and isomeric)
C(C(F)(F)F)(C(F)(F)F)(F)F

Synonyms

  • Perflutren
  • Octafluoropropane
  • 1,1,1,2,2,3,3,3-Octafluoropropane
  • Propane, octafluoro-
  • Freon 218
  • luminity
  • Oktafluorpropan
  • Genetron 218
  • Octafluorpropan
  • DMP 115
  • FC 218 (refrigerant)
  • FC 218
  • C3F8-gas
  • HFC 218
  • PFC 218
  • Perflutren Lipid Microsphere
  • perflutrene
  • Perflutreno
  • perflutrenum
  • Definity rt
  • Definity
  • UN 2424
  • Propane, 1,1,1,2,2,3,3,3-octafluoro-
  • Bovine Serum Albumin(BSA)
  • Recombinant Human Serum Albumin from Oryza sativa,OsrHSA
Show all 31 synonyms
  • Perflutren lipid microspheres
  • octafluoro-propane
  • Albumin Bovine V
  • Definity (TN)
  • Optison (Salt/Mix)
  • Perflutren-lipid microsphere

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless, nonflammable gasexp.
Melting point
-147.6 °Cexp.
Boiling point
-36.7 °Cexp.
Density
1.352 at 20 °C (liquid)exp.
Solubility
In water, 5.7 mg/L at 15 °Cexp.
Vapour pressure
6.63 × 10⁺³ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
188.02 g/molcalc.
Exact mass
187.9872 Dacalc.
LogP (octanol/water)
2.75calc.
Topological polar surface area
0 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
0calc.
Rotatable bonds
0calc.
Heavy atoms
11calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS04: Gas under pressure
Gas under pressure

Hazard statements

  • H280Contains gas under pressure, may explode if heated.
Precautionary statements (1)
  • P410 + P403Protect from sunlight. Store in a well-ventilated place.
UN number
UN 2424
Transport hazard class
2.2

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Perfluoropropane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 58 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

58 suppliers in 14 countries

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Perfluoropropane price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

High voltage insulating gas, refrigerant when combined with chlorofluoro hydrocarbons, plasma processing gas, fire protection agent.

Gaseous insulator, especially for radar waves guides.

Solvents (for cleaning and degreasing) in computer and electronic product manufacturing

Heat transfer agent

Foaming agent for protein fire fighting foams

Semiconductor industry (used extensiively in plasma etching processes and chemical vapour deposition (CVD) chamber cleaning to remove dielectric film build up. In a plasma with oxygen, it generates a variety of reactive species that breakdown chemical deposits to make volatile products, which are readily removed under vacuum.

Read more

Its cleaning effect is comparable to that of C2F6, but with significantly lower gas usage (up to 50%), offering important economic and environmental advantages.)

Dispersing agent for pharmaceutical

Used as an evaporative cooling fluid

Used in contrast imaging applications

Machinery and equipment

Retinal detachment surgery

Refrigerant.

Non-polymer PFAS -> Semiconductor Industry -> Etching the SiO2 coating of the semiconductor device

Non-polymer PFAS -> Electronic Industry -> Heat transfer fluids (cooling of electrical equipment)

Non-polymer PFAS -> Electronic Industry -> Sovent systems and cleaning

Non-polymer PFAS -> Semiconductor Industry -> Chemical vapour deposition chamber cleaning

Non-polymer PFAS -> Pharmaceuticals -> Dispersants in self-propelling aerosol pharmaceuticals

Non-polymer PFAS -> Refrigerant systems -> Refrigerants

Non-polymer PFAS -> Machinery and equipment -> (Electrical) machinery and equipment

Non-polymer PFAS -> Medicinal Utensils -> Contrast agent

Non-polymer PFAS -> Medicinal Utensils -> Retinal detachment surgery and proliferative vitreoretinopathy.

Cosmetic ingredient, INCI name PERFLUOROPROPANE(not reported)

Pharmacological actions

  • Contrast Media

Roles

  • antineoplastic agent
  • cardiovascular drug
  • pharmaceutical

Cosmetic functions

  • Not reported

Pharmacology

Perflutren is a Contrast Agent for Ultrasound Imaging. The mechanism of action of perflutren is as an Ultrasound Contrast Activity.

How it is made

Octafluoropropane (PFC 218) can be produced by direct, electrochemical, or CoF3-fluorination of commercially available hexafluoropropene.

Preparation: J.H. Simons, US 2456027 (1948 to Minnesota Mining Manufacturing)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Perfluoropropane is traded under.

HS 2903.49Indicative HS code

Saturated fluorinated derivatives of acyclic hydrocarbons, other

World exports in 2024
$124M
−2.2% vs 2023, imports $134M
2022 to 2024
Top exporters
  1. Japan29.8%
  2. United States28.1%
  3. China18.7%
Top importers
  1. South Korea41.2%
  2. United States9.5%
  3. Singapore7.0%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Perfluoropropane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Perfluoropropane, based on the data on this page

What is Perfluoropropane?

Octafluoropropane is a fluorocarbon that is propane in which all of the hydrogens have been replaced by fluorines. It is a fluoroalkane and a fluorocarbon. It derives from a hydride of a propane.

What is the CAS number of Perfluoropropane?

The CAS registry number of Perfluoropropane is 76-19-7.

What is the molecular formula and weight of Perfluoropropane?

The molecular formula of Perfluoropropane is C3F8 and its molar mass is 188.02 g/mol.

What is Perfluoropropane used for?

High voltage insulating gas, refrigerant when combined with chlorofluoro hydrocarbons, plasma processing gas, fire protection agent. Gaseous insulator, especially for radar waves guides.

Is Perfluoropropane hazardous?

Perfluoropropane carries the GHS signal word "Warning". Main hazards: contains gas under pressure, may explode if heated. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Perfluoropropane?

Perfluoropropane is usually classified under HS code 290349 (Saturated fluorinated derivatives of acyclic hydrocarbons, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Perfluoropropane?

CompoundList lists 58 suppliers of Perfluoropropane in China, United States, Germany, United Kingdom and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Perfluoropropane?

Suppliers quote Perfluoropropane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Perfluoropropane

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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