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Central nervous system drugs

Phencyclidine

Also known as 1-(1-Phenylcyclohexyl)piperidine, Angel dust, Fenciclidina

CAS 77-10-1Formula C17H25NMolar mass 243.39 g/molEC 621-588-0
GHS signal word: Danger. Pictograms: Acute toxicity (severe) Prohibited, not for trade
Why it is not for trade
Phencyclidine chemical structure, C17H25N, CAS 77-10-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White, crystalline powder
Melting point
46.5 °C
Boiling point
136 °C
Solubility
Soluble in ethanol
HS code
293333
Category
Central nervous system drugs

What is Phencyclidine?

Plain description, key identifiers and synonyms

Phencyclidine is a member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects. It has a role as a psychotropic drug, an anaesthetic, a neurotoxin and a NMDA receptor antagonist. It is a member of benzenes and a member of piperidines. It derives from a hydride of a piperidine.

Phencyclidine is an organic compound, often used as a street drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(1-phenylcyclohexyl)piperidine
CAS number
77-10-1 CAS number cross-checkedOther or deprecated CAS: 101887-87-0
EC number
621-588-0
Molecular formula
C17H25N
UNII
J1DOI7UV76
InChIKey
JTJMJGYZQZDUJJ-UHFFFAOYSA-N
InChI
InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2
SMILES (canonical and isomeric)
C1CCC(CC1)(C2=CC=CC=C2)N3CCCCC3

Synonyms

  • 1-(1-Phenylcyclohexyl)piperidine
  • Angel dust
  • Fenciclidina
  • Piperidine, 1-(1-phenylcyclohexyl)-
  • Phencyclidinum
  • Phencycline
  • Cl-395
  • Phenylcyclidine
  • CL 395
  • GP 121
  • Dust, Angel
  • PCP (Anesthetic)
  • Elephant tranquilizer
  • Peace pill
  • Tic Tac
  • Killer weed
  • HOG
  • 1-(Phenyl-1-cyclohexyl)piperidine
  • Supergrass
  • Cadillac
  • Crystal
  • Stardust
  • Surfer
  • Tranks
  • Whack
Show all 38 synonyms
  • Magic mist
  • Zombie dust
  • Busy bee
  • DEA No. 7471
  • Cycline
  • Cyclones
  • Scuffle
  • Sherman
  • Superjoint
  • Superweed
  • Sheets
  • Snorts
  • Aurora borealis

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White, crystalline powderexp.
Odour
Oily, slightly ammoniacexp.
Melting point
46.5 °Cexp.
Boiling point
136 °Cexp.
Solubility
Soluble in ethanolexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
243.39 g/molcalc.
Exact mass
243.1987 Dacalc.
LogP (octanol/water)
4.33calc.
Topological polar surface area
3.24 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
18calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.65calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C2(N3CCCCC3)CCCCC2)cc1

c1ccc(C2(N3CCCCC3)CCCCC2)cc1

3 rings, 18 atoms. This chemical is the scaffold itself.

74 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H301Toxic if swallowed.
  • H311Toxic in contact with skin.
  • H331Toxic if inhaled.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Phencyclidine suppliers

Trading restrictions apply to this substance

Narcotic drug

Phencyclidine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961, HS 2022 subheading 2933.33 (fentanyls and related analgesics)

Our policy on controlled substances

Phencyclidine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Phencyclidine (DEA Code Number: 7471) is a Schedule II controlled substance.

Schedule II Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions, and (C) Abuse of the drug or other substances may lead to severe psychological or physical dependence.

Ethylamine analog of phencyclidine (DEA Code Number: 7455), pyrrolidine analog of phencyclidine (DEA Code Number: 7471)and the thiophene analog of phencyclidine (DEA Code Number: 7470) are Schedule 1 controlled substances.

Read more

/Ethylamine analog of phencyclidine, pyrrolidine analog of phencyclidine, thiophene analog of phencyclidine/.

Schedule I Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has no currently accepted medical use in treatment in the United States, and (C) There is a lack of accepted safety for use of the drug or other substance under medical supervision.

Use classes: Pharmaceuticals.

Pharmacological actions

  • Enzyme Inhibitors
  • Excitatory Amino Acid Antagonists
  • Hallucinogens

Roles

  • NMDA receptor antagonist
  • aetiopathogenetic role
  • anaesthetic
  • antagonist
  • central nervous system drug
  • excitatory amino acid antagonist
  • neurotoxin
  • pharmaceutical
  • poison
  • psychotropic drug

Pharmacology

Phencyclidine is developed as an anesthetic for humans in 1959. Its use was discontinued due to extreme side effects that included delirium, confusion, visual disturbances, hallucinations and violence, some evidence of long-term memory disorders and schizophrenia-like syndrome has been observed. Phencyclidine, a substance of abuse also know as 'angel dust', can cause physical and psychological distresses, such as coma, seizures, convulsions, respiratory depression, and cardiac problems.

How it is made

Preparation: United Kingdom patent 836083 and Godefroi et al., United States of America patent 3097136 (1960, 1963 to Parke, Davis).

Regulatory status

Inventories, regulations and trade controls that list this substance

Narcotic drug

Phencyclidine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961, HS 2022 subheading 2933.33 (fentanyls and related analgesics)

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled narcotic drug

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Phencyclidine is traded under.

HS 2933.33Exact HS code

Alfentanil (INN), anileridine (INN), bezitramide (INN), bromazepam (INN), carfentanil…

World exports in 2024
$83.8M
+13.4% vs 2023, imports $95.2M
2019 to 2024
Top exporters
  1. Switzerland * partner reported31.1%
  2. United States17.5%
  3. India * partner reported16.0%
Top importers
  1. Germany27.9%
  2. Spain12.8%
  3. Brazil9.4%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Phencyclidine is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Phencyclidine, based on the data on this page

What is Phencyclidine?

Phencyclidine is a member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.

What is the CAS number of Phencyclidine?

The CAS registry number of Phencyclidine is 77-10-1. Other or deprecated CAS numbers: 101887-87-0.

What is the molecular formula and weight of Phencyclidine?

The molecular formula of Phencyclidine is C17H25N and its molar mass is 243.39 g/mol.

What is Phencyclidine used for?

Phencyclidine (DEA Code Number: 7471) is a Schedule II controlled substance. Schedule II Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with…

Is Phencyclidine hazardous?

Phencyclidine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, toxic in contact with skin, toxic if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Phencyclidine?

Phencyclidine is usually classified under HS code 293333 (Alfentanil (INN), anileridine (INN), bezitramide (INN), bromazepam (INN), carfentanil…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Phencyclidine on CompoundList?

No. Phencyclidine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Phencyclidine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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