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Cardiovascular and metabolic drugs

Pilsicainide

Also known as Pilzicainide, Pilsicainida, Pilsicainidum

CAS 88069-67-4Formula C17H24N2OMolar mass 272.39 g/mol
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Pilsicainide chemical structure, C17H24N2O, CAS 88069-67-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
88069-67-4
Formula
C17H24N2O
Molar mass
272.39 g/mol
HS code
293399
Category
Cardiovascular and metabolic drugs

What is Pilsicainide?

Plain description, key identifiers and synonyms

Pilsicainide is a secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan. It has a role as an anti-arrhythmia drug and a sodium channel blocker. It is a secondary carboxamide and an organic heterobicyclic compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
CAS number
88069-67-4 CAS number cross-checked
Molecular formula
C17H24N2O
UNII
AV0X7V6CSE
InChIKey
BCQTVJKBTWGHCX-UHFFFAOYSA-N
InChI
InChI=1S/C17H24N2O/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20)
SMILES (canonical and isomeric)
CC1=C(C(=CC=C1)C)NC(=O)CC23CCCN2CCC3

Synonyms

  • Pilzicainide
  • Pilsicainida
  • Pilsicainidum
  • N-(2,6-Dimethylphenyl)-2-(hexahydro-1H-pyrrolizin-7a-yl)acetamide
  • Tetrahydro-1H-pyrrolizine-7a(5H)-aceto-2',6'-xylidide
  • N-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide
  • N-(2,6-Dimethylphenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide
  • Pilsicainide (INN)
  • 1H-Pyrrolizine-7a(5H)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
272.39 g/molcalc.
Exact mass
272.1889 Dacalc.
LogP (octanol/water)
3.26calc.
Topological polar surface area
32.34 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.59calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CC12CCCN1CCC2)Nc1ccccc1

O=C(CC12CCCN1CCC2)Nc1ccccc1

3 rings, 18 atoms.

35 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Pilsicainide suppliers

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All 4 suppliers
4 of 4 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 3 countries

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Pilsicainide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Arrhythmia Agents
  • Sodium Channel Blockers

Roles

  • anti-arrhythmia drug
  • biophysical role
  • cardiovascular drug
  • membrane transport modulator
  • pharmaceutical
  • sodium channel blocker
  • sodium channel modulator

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pilsicainide is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pilsicainide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pilsicainide, based on the data on this page

What is Pilsicainide?

Pilsicainide is a secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid.

What is the CAS number of Pilsicainide?

The CAS registry number of Pilsicainide is 88069-67-4.

What is the molecular formula and weight of Pilsicainide?

The molecular formula of Pilsicainide is C17H24N2O and its molar mass is 272.39 g/mol.

What is Pilsicainide used for?

Known uses and roles of Pilsicainide include cardiovascular drugs in pharmaceuticals, anti-arrhythmia drug, biophysical role, cardiovascular drug, membrane transport modulator and 5 more.

Is Pilsicainide hazardous?

No GHS hazard classification for Pilsicainide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Pilsicainide?

Pilsicainide is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pilsicainide?

CompoundList lists 4 suppliers of Pilsicainide in Japan, China and South Korea. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Pilsicainide?

Suppliers quote Pilsicainide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pilsicainide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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