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Central nervous system drugs

Pipamperone

Also known as Floropipamide, Dipiperone, Pipamperona

CAS 1893-33-0Formula C21H30FN3O2Molar mass 375.49 g/molEC 606-172-9
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant, Hazardous to the environment 4 suppliers listed
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Pipamperone chemical structure, C21H30FN3O2, CAS 1893-33-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1893-33-0
Formula
C21H30FN3O2
Molar mass
375.49 g/mol
EC number
606-172-9
HS code
293339
Category
Central nervous system drugs

What is Pipamperone?

Plain description, key identifiers and synonyms

Pipamperone is a member of the class of bipiperidines that is 1,4'-bipiperidine which is substituted at the 1' and 4' positions by 4-(p-fluorophenyl)-4-oxobutyl and carboxamide groups, respectively. A first generation antipsychotic, its properties are generally similar to those of haloperidol. It has a role as a serotonergic antagonist, a dopaminergic antagonist and a first generation antipsychotic. It is a monocarboxylic acid amide, an organofluorine compound, a member of bipiperidines, a tertiary amino compound and an aromatic ketone. It is a conjugate base of a pipamperone(2+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS number
1893-33-0 CAS number cross-checked
EC number
606-172-9
Molecular formula
C21H30FN3O2
UNII
5402501F0W
MDL number
MFCD00242979
InChIKey
AXKPFOAXAHJUAG-UHFFFAOYSA-N
InChI
InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27)
SMILES (canonical and isomeric)
C1CCN(CC1)C2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C(=O)N

Synonyms

  • Floropipamide
  • Dipiperone
  • Pipamperona
  • Pipamperonum
  • 1'-(3-(p-Fluorobenzoyl)propyl)-(1,4'-bipiperidine)-4'-carboxamide
  • p-Fluoro-gamma-(4-piperidino-4-carbamoylpiperidino)butyrophenone
  • 1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidin-1-ylpiperidine-4-carboxamide
  • (1,4'-Bipiperidine)-4'-carboxamide, 1'-(4-(4-fluorophenyl)-4-oxobutyl)-
  • [1,4'-Bipiperidine]-4'-carboxamide, 1'-[4-(4-fluorophenyl)-4-oxobutyl]-
  • 1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidin-1-ylpiperidine-4-carboxamide
  • 1'-(3-(4-fluorobenzoyl)propyl)-(1,4'-bipiperidine)-4'-carboxamide
  • 1'-(4-(4-Fluoro-phenyl)-4-oxo-butyl)-(1,4')bipiperidinyl-4'-carboxylic acid amide
  • Dipiperon
  • Piperonyl
  • Dipiperal
  • Pipamperone free base
  • McN-JR-3345
  • Pipaneperone
  • Pipamperone dihydrochloride approx. 99
  • (1,4'-BIPIPERIDINE)-4'-CARBOXAMIDE, 1'-(3-(p-FLUOROBENZOYL)PROPYL)-
  • 4'-Fluoro-4-(4-N-piperidino-4-carbamidopiperidino)butyrophenone
  • Floropipamide, McN-JR 3345, R 3345
  • 1'-[4-(4-fluorophenyl)-4-oxobutyl]-1,4'-bipiperidine-4'-carboxamide
  • 1'-(4-(4-fluorophenyl)-4-oxobutyl)-[1,4'-bipiperidine]-4'-carboxamide
  • 1'-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4'-bipiperidine]-4'-carboxamide
Show all 33 synonyms
  • Carpiperone
  • Fluoropipamide
  • Pipamperon
  • 1'-(4-(4-fluorophenyl)-4-oxobutyl)-1,4'-bipiperidine-4'-carboxamide
  • 1893-33-0 (free base)
  • Propitan (Salt/Mix)
  • Pipamperone (Standard)
  • Isonipacotamide, 1-(3-(p-fluorobenzoyl)propyl)-4-piperidino-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
375.49 g/molcalc.
Exact mass
375.2322 Dacalc.
LogP (octanol/water)
2.59calc.
Topological polar surface area
66.64 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
7calc.
Heavy atoms
27calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.62calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CCCN1CCC(N2CCCCC2)CC1)c1ccccc1

O=C(CCCN1CCC(N2CCCCC2)CC1)c1ccccc1

3 rings, 23 atoms.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H301Toxic if swallowed.
  • H302 + H312 + H332Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.
  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Pipamperone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers

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Where suppliers are based

4 suppliers in 3 countries

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Pipamperone price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Antipsychotic Agents
  • Serotonin Antagonists

Roles

  • antagonist
  • antidepressant
  • antipsychotic agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • dopaminergic agent
  • dopaminergic antagonist
  • first generation antipsychotic
  • neurotransmitter agent
  • pharmaceutical
  • psychotropic drug
  • serotonergic antagonist
  • serotonergic drug
  • tranquilizing drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Pipamperone is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Pipamperone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Pipamperone, based on the data on this page

What is Pipamperone?

Pipamperone is a member of the class of bipiperidines that is 1,4'-bipiperidine which is substituted at the 1' and 4' positions by 4-(p-fluorophenyl)-4-oxobutyl and carboxamide groups, respectively. A first generation antipsychotic, its properties are generally similar to those of haloperidol.

What is the CAS number of Pipamperone?

The CAS registry number of Pipamperone is 1893-33-0.

What is the molecular formula and weight of Pipamperone?

The molecular formula of Pipamperone is C21H30FN3O2 and its molar mass is 375.49 g/mol.

What is Pipamperone used for?

Use classes: Pharmaceuticals.

Is Pipamperone hazardous?

Pipamperone carries the GHS signal word "Danger". Main hazards: toxic if swallowed, harmful if swallowed. harmful in contact with skin. harmful if inhaled, harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Pipamperone?

Pipamperone is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Pipamperone?

CompoundList lists 4 suppliers of Pipamperone in United States, China and India. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Pipamperone in India?

1 supplier in India list Pipamperone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Pipamperone?

Suppliers quote Pipamperone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Pipamperone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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