CompoundList
Sign in
Antibiotics and anti-infectives

Primaquine

Also known as Primachin, 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline, Neo-Quipenyl

CAS 90-34-6Formula C15H21N3OMolar mass 259.35 g/molEC 201-987-2
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 72 suppliers listed Drug substance
Get quotes Compare 72 suppliers
Primaquine chemical structure, C15H21N3O, CAS 90-34-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
90-34-6
Formula
C15H21N3O
Appearance
Viscous liquid
Boiling point
175 to 179
HS code
293349
Category
Antibiotics and anti-infectives
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Primaquine?

Plain description, key identifiers and synonyms

Primaquine is an N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N4 position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia. It has a role as an antimalarial. It is an aromatic ether, an aminoquinoline and a N-substituted diamine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
CAS number
90-34-6 CAS number cross-checked
EC number
201-987-2
Molecular formula
C15H21N3O
UNII
MVR3634GX1
MDL number
MFCD00598906
InChIKey
INDBQLZJXZLFIT-UHFFFAOYSA-N
InChI
InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3
SMILES (canonical and isomeric)
CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2

Synonyms

  • Primachin
  • 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline
  • Neo-Quipenyl
  • Primaquin
  • Primachinum
  • Primaquina
  • Primaquinum
  • Kanaprim
  • Primachina
  • 1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-
  • 4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
  • Maliride
  • 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline
  • N-(5-aminopentan-2-yl)-6-methoxyquinolin-8-amine
  • 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline
  • N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
  • 8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinoline
  • dl-Primaquine
  • (+/-)-Primaquine
  • SN 13,272
  • S. N. 13272
  • N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine
  • Primaquine (INN)
  • N4-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
  • N4-(6-methoxy-8-quinolyl)pentane-1,4-diamine
Show all 33 synonyms
  • (-)-N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine
  • 1,4-Pentanediamine, N(4)-(6-methoxy-8-quinolinyl)-
  • N-[(S)-4-Amino-1-methylbutyl]-6-methoxy-8-quinolinamine
  • Maliride, NSC 27296, Neo-Quipenyl, Primachin
  • N~4~-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
  • 6-Methoxy-8-[(4-amino-1-methylbutyl)amino]quinoline
  • Quinoline, 8-((4-amino-1-methylbutyl)amino)-6-methoxy-
  • Kanaprim (TN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Viscous liquidexp.
Boiling point
175 to 179exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
259.35 g/molcalc.
Exact mass
259.1685 Dacalc.
LogP (octanol/water)
2.78calc.
Topological polar surface area
60.17 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
6calc.
Heavy atoms
19calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2ncccc2c1

c1ccc2ncccc2c1

2 rings, 10 atoms, the Quinoline ring system.

21,766 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H361dSuspected of damaging the unborn child.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Primaquine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 72 suppliers
30 of 30 offers
  • Faes Farma, SA
    Spain, Leioa ManufacturerUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • Pursuit Industries Pvt Ltd
    India ManufacturerUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • Namau Chem Pvt. Ltd
    India ManufacturerUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • Lenntech
    Netherlands, DelftUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • 001Chemical
    China, HangzhouUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • 10X Chem
    United States, San DiegoUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • 3WAY Pharm Inc
    China, ShanghaiUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • A2B Chem LLC
    United States, San DiegoUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • Aa Blocks LLC
    United States, San DiegoUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View
  • Aaron Chemicals LLC.
    China, NanjingUnclaimed profile
    PrimaquineGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

72 suppliers in 13 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Primaquine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Antimalarial.

Pharmacological actions

  • Antimalarials

Roles

  • anti-obesity agent
  • antifungal agent
  • antiinfective agent
  • antimalarial
  • antimicrobial agent
  • antimicrobial drug
  • antiparasitic agent
  • antiplasmodial drug
  • antiprotozoal drug
  • antiviral agent
  • pharmaceutical

Pharmacology

Primaquine is an Antimalarial.

How it is made

Synthesis: 6-Methoxy-8-aminoquinoline is condensed with 1-phthalimido-4-bromopentane, and the phthalyl group is cleaved by heating with hydrazine in ethanol and hydrochloric acid.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Primaquine is traded under.

HS 2933.49Indicative HS code

Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…

World exports in 2024
$939M
−14.6% vs 2023, imports $1.48B
2019 to 2024
Top exporters
  1. China30.1%
  2. India * partner reported16.7%
  3. Switzerland * partner reported14.1%
Top importers
  1. United Kingdom19.2%
  2. Germany16.0%
  3. Romania8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Primaquine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Primaquine, based on the data on this page

What is Primaquine?

Primaquine is an N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N4 position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia. It has a role as an antimalarial. It is an aromatic ether, an aminoquinoline and a N-substituted diamine.

What is the CAS number of Primaquine?

The CAS registry number of Primaquine is 90-34-6.

What is the molecular formula and weight of Primaquine?

The molecular formula of Primaquine is C15H21N3O and its molar mass is 259.35 g/mol.

What is Primaquine used for?

Antimalarial.

Is Primaquine hazardous?

Primaquine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, suspected of damaging the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Primaquine?

Primaquine is usually classified under HS code 293349 (Compounds containing in the structure a quinoline or isoquinoline ring-system (whether…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Primaquine?

CompoundList lists 72 suppliers of Primaquine in United States, China, United Kingdom, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Primaquine in India?

2 suppliers in India list Primaquine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Primaquine?

Suppliers quote Primaquine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Primaquine

Get quotes for Primaquine

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Primaquine
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Primaquine with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/primaquine-90-34-6" title="Primaquine structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Antibiotics and anti-infectives or HS code 293349

72 suppliers
Free quotes, contact stays private
Get quotes