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Respiratory, allergy and digestive drugs

Ranitidine

Also known as Ranitidinum, Ranitidina, Gavilast

CAS 66357-35-5Formula C13H22N4O3SMolar mass 314.41 g/molEC 266-332-5
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 96 suppliers listed Drug substance
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Ranitidine chemical structure, C13H22N4O3S, CAS 66357-35-5
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Solid
Melting point
69 to 70
Solubility
Water soluble
HS code
293219
Category
Respiratory, allergy and digestive drugs
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Ranitidine?

Plain description, key identifiers and synonyms

Ranitidine is a member of the class of furans used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease. It has a role as a xenobiotic, a H2-receptor antagonist, an anti-ulcer drug, an environmental contaminant and a drug allergen. It is an organic sulfide, a member of furans, a C-nitro compound and a tertiary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
CAS number
66357-35-5 CAS number cross-checkedOther or deprecated CAS: 66357-59-3, 82530-72-1
EC number
266-332-5
Molecular formula
C13H22N4O3S
MDL number
MFCD00081180
InChIKey
VMXUWOKSQNHOCA-UKTHLTGXSA-N
InChI
InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+
Canonical SMILES
CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1
Isomeric SMILES
CN/C(=C\[N+](=O)[O-])/NCCSCC1=CC=C(O1)CN(C)C

Synonyms

  • Ranitidinum
  • Ranitidina
  • Gavilast
  • Ranitidin
  • n-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-n'-methyl-2-nitro-1,1-ethenediamine
  • 1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro-
  • 1,1-Ethenediamine, N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-
  • (E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
  • dimethyl[(5-{[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine
  • (E)-1-N'-(2-((5-((dimethylamino)methyl)furan-2-yl)methylsulfanyl)ethyl)-1-N-methyl-2-nitroethene-1,1-diamine
  • dimethyl((5-(((2-(((E)-1-(methylamino)-2-nitroethenyl)amino)ethyl)sulfanyl)methyl)furan-2-yl)methyl)amine
  • n-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-n'-methyl-2-nitro-1,1-ethenediamine
  • N-(2-((5-(dimethylaminomethyl)furan-2-yl)methylsulfanyl)ethyl)-N'-methyl-2-nitroethene-1,1-diamine
  • N-[2-[[5-(dimethylaminomethyl)furan-2-yl]methylsulfanyl]ethyl]-N'-methyl-2-nitroethene-1,1-diamine
  • Hydrochloride, Ranitidine
  • N (2-(((5-((Dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine
  • Ranitidine bismutrex
  • Ranitidine Base
  • Ratic
  • Raticina
  • Quantor
  • Rantidine
  • Gastrosedol
  • Microtid
  • Ptinolin
Show all 38 synonyms
  • Ranidine
  • Raniogas
  • Ranitiget
  • Rantacid
  • Taural
  • Duractin
  • Ulceranin
  • Weichilin
  • Xanidine
  • Zantadin
  • Achedos
  • Acidex
  • Atural

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Solidexp.
Odour
Characteristicexp.
Taste
Bitter tasteexp.
Melting point
69 to 70exp.
Solubility
Water solubleexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
314.41 g/molcalc.
Exact mass
314.1413 Dacalc.
LogP (octanol/water)
1.46calc.
Topological polar surface area
83.58 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
10calc.
Heavy atoms
21calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.54calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccoc1

c1ccoc1

1 ring, 5 atoms, the Furan ring system.

12,988 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (20)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ranitidine suppliers

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All 96 suppliers
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Where suppliers are based

96 suppliers in 18 countries

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Ranitidine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Alimentary tract and metabolism.

Pharmacological actions

  • Anti-Ulcer Agents
  • Histamine H2 Antagonists

Roles

  • H2-receptor antagonist
  • aetiopathogenetic role
  • allergen
  • antagonist
  • anti-ulcer drug
  • drug allergen
  • environmental contaminant
  • histamine antagonist
  • histaminergic drug
  • neurotransmitter agent
  • pharmaceutical
  • xenobiotic

Functional uses

  • Pharmaceutical

Pharmacology

Ranitidine is a Histamine-2 Receptor Antagonist. The mechanism of action of ranitidine is as a Histamine H2 Receptor Antagonist.

How it is made

Synthesized from nitromethane.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ranitidine is traded under.

HS 2932.19Indicative HS code

Compounds containing an unfused furan ring (whether or not hydrogenated) in the…

World exports in 2024
$2.62B
−6.4% vs 2023, imports $2.56B
2019 to 2024
Top exporters
  1. Germany57.9%
  2. Italy11.5%
  3. China10.4%
Top importers
  1. Greece40.4%
  2. Japan16.3%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ranitidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ranitidine, based on the data on this page

What is Ranitidine?

Ranitidine is a member of the class of furans used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease. It has a role as a xenobiotic, a H2-receptor antagonist, an anti-ulcer drug, an environmental contaminant and a drug allergen.

What is the CAS number of Ranitidine?

The CAS registry number of Ranitidine is 66357-35-5. Other or deprecated CAS numbers: 66357-59-3, 82530-72-1.

What is the molecular formula and weight of Ranitidine?

The molecular formula of Ranitidine is C13H22N4O3S and its molar mass is 314.41 g/mol.

What is Ranitidine used for?

Use classes: Alimentary tract and metabolism.

Is Ranitidine hazardous?

Ranitidine carries the GHS signal word "Danger". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ranitidine?

Ranitidine is usually classified under HS code 293219 (Compounds containing an unfused furan ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ranitidine?

CompoundList lists 96 suppliers of Ranitidine in United States, China, India, Bangladesh and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ranitidine in India?

19 suppliers in India list Ranitidine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ranitidine?

Suppliers quote Ranitidine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ranitidine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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