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Pharmaceuticals and APIs

Ranitidine hydrochloride

Also known as Ranitidine HCL, Azantac, Ranibloc

CAS 66357-59-3Formula C13H23ClN4O3SMolar mass 350.87 g/molEC 266-333-0
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 93 suppliers listed Drug substance
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Ranitidine hydrochloride chemical structure, C13H23ClN4O3S, CAS 66357-59-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
66357-59-3
Formula
C13H23ClN4O3S
Molar mass
350.87 g/mol
EC number
266-333-0
HS code
293219
Category
Pharmaceuticals and APIs

What is Ranitidine hydrochloride?

Plain description, key identifiers and synonyms

Ranitidine Hydrochloride is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine, hydrochloride
CAS number
66357-59-3Other or deprecated CAS: 71130-06-8
EC numbers
266-333-0, 275-207-4
Molecular formula
C13H23ClN4O3S
MDL number
MFCD00069339
InChIKey
GGWBHVILAJZWKJ-KJEVSKRMSA-N
InChI
InChI=1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9+;
Canonical SMILES
CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.Cl
Isomeric SMILES
CN/C(=C\[N+](=O)[O-])/NCCSCC1=CC=C(O1)CN(C)C.Cl

Synonyms

  • Ranitidine HCL
  • Azantac
  • Ranibloc
  • Nu-Ranit
  • Rani-Q
  • Fendibina
  • Gastridina
  • Gastrolav
  • Kuracid
  • Alquen
  • Zantac In Plastic Container
  • Rani-nerton
  • Zantac 300
  • Ranitic
  • Coralen
  • Wal-zan 75
  • Ranitidine-Acid Reducer
  • Zantac 75
  • Zantac 150
  • Ranitidine Tablet USP, 75mg
  • AH 19065
  • Gastrial
  • Zantac 25
  • Gabitidine
  • Sentradine
Show all 39 synonyms
  • Dumoran
  • Ranicalm
  • Raniplex
  • Ranitil
  • Vivatak
  • Histac
  • ranitidine.hcl
  • Rantec
  • Ranzac
  • Gavilast-p
  • Heratburn Relief
  • Wal-zan
  • Ranitidine 75
  • Aptidine 75

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
350.87 g/molcalc.
Exact mass
350.1179 Dacalc.
LogP (octanol/water)
1.88calc.
Topological polar surface area
83.58 ร…ยฒcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
10calc.
Heavy atoms
22calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.54calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccoc1

c1ccoc1

1 ring, 5 atoms, the Furan ring system.

12,988 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (23)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403Store in a well-ventilated place.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ranitidine hydrochloride suppliers

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All 93 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

93 suppliers in 17 countries

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Ranitidine hydrochloride price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • aetiopathogenetic role
  • allergen
  • drug allergen
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ranitidine hydrochloride is traded under.

HS 2932.19Indicative HS code

Compounds containing an unfused furan ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$2.62B
โˆ’6.4% vs 2023, imports $2.56B
2019 to 2024
Top exporters
  1. Germany57.9%
  2. Italy11.5%
  3. China10.4%
Top importers
  1. Greece40.4%
  2. Japan16.3%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Ranitidine hydrochloride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ranitidine hydrochloride, based on the data on this page

What is Ranitidine hydrochloride?

Ranitidine Hydrochloride is a member of the class of histamine H2-receptor antagonists with antacid activity.

What is the CAS number of Ranitidine hydrochloride?

The CAS registry number of Ranitidine hydrochloride is 66357-59-3. Other or deprecated CAS numbers: 71130-06-8.

What is the molecular formula and weight of Ranitidine hydrochloride?

The molecular formula of Ranitidine hydrochloride is C13H23ClN4O3S and its molar mass is 350.87 g/mol.

What is Ranitidine hydrochloride used for?

Known uses and roles of Ranitidine hydrochloride include aetiopathogenetic role, allergen, drug allergen and pharmaceutical.

Is Ranitidine hydrochloride hazardous?

Ranitidine hydrochloride carries the GHS signal word "Danger". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ranitidine hydrochloride?

Ranitidine hydrochloride is usually classified under HS code 293219 (Compounds containing an unfused furan ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ranitidine hydrochloride?

CompoundList lists 93 suppliers of Ranitidine hydrochloride in United States, China, India, United Kingdom and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ranitidine hydrochloride in India?

19 suppliers in India list Ranitidine hydrochloride on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ranitidine hydrochloride?

Suppliers quote Ranitidine hydrochloride on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ranitidine hydrochloride

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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