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Analgesics and anti-inflammatories

Robenacoxib

Also known as Onsior, 2-(5-Ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic acid, robenacoxibum

CAS 220991-32-2Formula C16H13F4NO2Molar mass 327.28 g/molEC 684-585-3
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 12 suppliers listed Drug substance
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Robenacoxib chemical structure, C16H13F4NO2, CAS 220991-32-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
220991-32-2
Formula
C16H13F4NO2
Molar mass
327.28 g/mol
EC number
684-585-3
HS code
292249
Category
Analgesics and anti-inflammatories

What is Robenacoxib?

Plain description, key identifiers and synonyms

Robenacoxib is an aromatic amino acid that is 2-amino-5-ethylphenylacetic acid in which one of the amino hydrogens is replaced by a 2,3,5,6-tetrafluorophenyl group. A selective cyclooxygenase 2 inhibitor that is used in veterinary medicine for the relief of pain and inflammation in cats and dogs. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and a cyclooxygenase 2 inhibitor. It is a monocarboxylic acid, a member of phenylacetic acids, an aromatic amino acid, an organofluorine compound and a secondary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[5-ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl]acetic acid
CAS number
220991-32-2 CAS number cross-checked
EC number
684-585-3
Molecular formula
C16H13F4NO2
UNII
Z588009C7C
MDL number
MFCD27966869
InChIKey
ZEXGDYFACFXQPF-UHFFFAOYSA-N
InChI
InChI=1S/C16H13F4NO2/c1-2-8-3-4-12(9(5-8)6-13(22)23)21-16-14(19)10(17)7-11(18)15(16)20/h3-5,7,21H,2,6H2,1H3,(H,22,23)
SMILES (canonical and isomeric)
CCC1=CC(=C(C=C1)NC2=C(C(=CC(=C2F)F)F)F)CC(=O)O

Synonyms

  • Onsior
  • 2-(5-Ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic acid
  • robenacoxibum
  • (5-Ethyl-2-((2,3,5,6-tetrafluorophenyl)amino)phenyl)acetic acid
  • onsior injection
  • {5-ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]phenyl}acetic acid
  • onsior Tablets for Cats
  • 2-[5-ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl]acetic acid
  • CGS 34975
  • Robecoxib
  • Robenacoxib (Standard)
  • 5-Ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]benzeneacetic Acid
  • Robenacoxib-d5Q: What is
  • Onsior, CGS 34975
  • Robenacoxib-d5 Q: What is the CAS Number of
  • [5-Ethyl-2-(2,3,5,6-tetrafluoroanilino)phenyl]acetic acid
  • 5-ethyl-2-(2',3',5',6'-tetrafluoroanilino)phenylacetic acid
  • 5-ethyl-2-(2', 3', 5', 6'-tetrafluoroanilino)phenylacetic acid
  • 5-ethyl-2-(2', 3',5',6'-tetrafluoroanilino)phenylacetic acid
  • 5-ethyl-2-(2',3',5', 6'-tetrafluoroanilino)phenylacetic acid
  • 5-ethyl-2-(2',3',5',6'-tetrafluoroanilino) phenylacetic acid
  • Benzeneacetic acid, 5-ethyl-2-[(2,3,5,6-tetrafluorophenyl)amino]-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
327.28 g/molcalc.
Exact mass
327.0882 Dacalc.
LogP (octanol/water)
4.18calc.
Topological polar surface area
49.33 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
5calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.19calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Nc2ccccc2)cc1

c1ccc(Nc2ccccc2)cc1

2 rings, 13 atoms, the Diphenylamine ring system.

3,181 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H361Suspected of damaging fertility or the unborn child.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Robenacoxib suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 12 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

12 suppliers in 5 countries

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Robenacoxib price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Roles

  • analgesic
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • cyclooxygenase 2 inhibitor
  • enzyme inhibitor
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Robenacoxib is traded under.

HS 2922.49Indicative HS code

Amino-acids, other than those containing more than one kind of oxygen function, and…

World exports in 2024
$3.88B
−11.5% vs 2023, imports $3.87B
2019 to 2024
Top exporters
  1. China38.7%
  2. India * partner reported8.3%
  3. Germany8.1%
Top importers
  1. United States13.4%
  2. Germany11.1%
  3. Japan6.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Robenacoxib is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Robenacoxib, based on the data on this page

What is Robenacoxib?

Robenacoxib is an aromatic amino acid that is 2-amino-5-ethylphenylacetic acid in which one of the amino hydrogens is replaced by a 2,3,5,6-tetrafluorophenyl group. A selective cyclooxygenase 2 inhibitor that is used in veterinary medicine for the relief of pain and inflammation in cats and dogs.

What is the CAS number of Robenacoxib?

The CAS registry number of Robenacoxib is 220991-32-2.

What is the molecular formula and weight of Robenacoxib?

The molecular formula of Robenacoxib is C16H13F4NO2 and its molar mass is 327.28 g/mol.

What is Robenacoxib used for?

Use classes: Animal Drugs.

Is Robenacoxib hazardous?

Robenacoxib carries the GHS signal word "Warning". Main hazards: harmful if swallowed, suspected of damaging fertility or the unborn child, harmful to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Robenacoxib?

Robenacoxib is usually classified under HS code 292249 (Amino-acids, other than those containing more than one kind of oxygen function, and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Robenacoxib?

CompoundList lists 12 suppliers of Robenacoxib in China, India, United States, Germany and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Robenacoxib in India?

2 suppliers in India list Robenacoxib on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Robenacoxib?

Suppliers quote Robenacoxib on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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