CompoundList
Sign in
Synthetic aroma chemicals

Skatole

Also known as 3-Methylindole, 3-Methyl-1H-indole, Scatole

CAS 83-34-1Formula C9H9NMolar mass 131.18 g/molEC 201-471-7
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 108 suppliers listed Drug substance
Get quotes Compare 108 suppliers
Skatole chemical structure, C9H9N, CAS 83-34-1
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Leaves from petroleum ether, white-brown scales
Melting point
95 °C
Boiling point
265 to 266
Solubility
SOL IN HOT WATER, ALC, BENZENE, CHLOROFORM, ETHER
HS code
293399
Category
Synthetic aroma chemicals
Illustrative photo, white flakes in a glass jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Skatole?

Plain description, key identifiers and synonyms

Skatole is a methylindole carrying a methyl substituent at position 3. It is produced during the anoxic metabolism of L-tryptophan in the mammalian digestive tract. It has a role as a mammalian metabolite and a human metabolite.

Skatole is a compound that causes fecal odor.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-methyl-1H-indole
CAS number
83-34-1 CAS number cross-checked
EC number
201-471-7
Molecular formula
C9H9N
UNII
9W945B5H7R
MDL number
MFCD00005627
INCI name
SKATOLE
InChIKey
ZFRKQXVRDFCRJG-UHFFFAOYSA-N
InChI
InChI=1S/C9H9N/c1-7-6-10-9-5-3-2-4-8(7)9/h2-6,10H,1H3
SMILES (canonical and isomeric)
CC1=CNC2=CC=CC=C12

Synonyms

  • 3-Methylindole
  • 3-Methyl-1H-indole
  • Scatole
  • 1H-Indole, 3-methyl-
  • Skatol
  • Indole, 3-methyl-
  • beta-Methylindole
  • 3-methyl-indole
  • Skatolum
  • 3 Methylindole
  • 3-methyl indole
  • 3-Methyl-4,5-benzopyrrole
  • Skatole, >=98%
  • b-Methylindole
  • U 34908, 16a,17-Dihydroxy-corticosterone, 11ss,16a,17,21-Tetrahydroxy-pregn-4-ene-3,20-dione, 11ss,16a,17,21-Tetrahydroxypregn-4-ene-3,20-dione
  • Skatole (Standard)
  • 3-methyl-1H-indol
  • 16alpha-Hydroxycortisol
  • 3-Methylindole, 98%
  • 3-Methylindole, analytical standard
  • 3-Methylindole Solution in Methanol, 100ug/mL
  • 3-Methylindole Solution in Methanol, 1000ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Leaves from petroleum ether, white-brown scalesexp.
Odour
CHARACTERISTIC FECAL ODOR AT HIGH LEVELS, BECOMING PLEASANT, SWEET, AND WARM AT VERY LOW LEVELSexp.
Taste
WARM, OVER-RIPE, FRUITY FLAVOR BELOW 0.1 PPMexp.
Melting point
95 °Cexp.
Boiling point
265 to 266exp.
Solubility
SOL IN HOT WATER, ALC, BENZENE, CHLOROFORM, ETHERexp.
Vapour pressure
0.0055 mm Hgexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
131.18 g/molcalc.
Exact mass
131.0735 Dacalc.
LogP (octanol/water)
2.48calc.
Topological polar surface area
15.79 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
0calc.
Rotatable bonds
0calc.
Heavy atoms
10calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.11calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2[nH]ccc2c1

c1ccc2[nH]ccc2c1

2 rings, 9 atoms, the Indole ring system.

25,097 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (18)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Skatole suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 108 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

108 suppliers in 18 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Skatole price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

In perfumery (fixative), artificial civet.

Flavoring food additive.

Cosmetic ingredient, INCI name SKATOLE(perfuming)

Roles

  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite

Functional uses

  • Flavouring and nutrient
  • Fragrance

Cosmetic functions

  • Perfuming

How it is made

Obtained by fusing egg albumin with potassium hydroxide.

Synthesized...by heating glycerol and aniline in the presence of zinc chloride, also by treating the phenylhydrazone of propionic aldehyde with a calculated amt of zinc chloride in an oil bath @ 180 °c...

By cyclization of o-toluidides.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Skatole is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Skatole is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Skatole, based on the data on this page

What is Skatole?

Skatole is a methylindole carrying a methyl substituent at position 3. It is produced during the anoxic metabolism of L-tryptophan in the mammalian digestive tract. It has a role as a mammalian metabolite and a human metabolite.

What is the CAS number of Skatole?

The CAS registry number of Skatole is 83-34-1.

What is the molecular formula and weight of Skatole?

The molecular formula of Skatole is C9H9N and its molar mass is 131.18 g/mol.

What is Skatole used for?

In perfumery (fixative), artificial civet. Flavoring food additive.

Is Skatole hazardous?

Skatole carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Skatole?

Skatole is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Skatole?

CompoundList lists 108 suppliers of Skatole in China, United States, United Kingdom, Germany and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Skatole in India?

3 suppliers in India list Skatole on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Skatole?

Suppliers quote Skatole on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Skatole

Get quotes for Skatole

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Skatole
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Skatole with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/skatole-83-34-1" title="Skatole structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Synthetic aroma chemicals or HS code 293399

108 suppliers
Free quotes, contact stays private
Get quotes