Srt-2183 (CAS 1001908-89-9): price, suppliers and safety

What is Srt-2183?

Plain description, key identifiers and synonyms

Srt-2183 is a chemical substance with the molecular formula C27H24N4O2S and a molar mass of 468.58 g/mol. Its CAS registry number is 1001908-89-9. The IUPAC name is N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name: N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide
CAS number: 1001908-89-9 CAS number cross-checked
Molecular formula: C₂₇H₂₄N₄O₂S
UNII: 6FKU9G9CX6
MDL number: MFCD22419825
InChIKey: MUFSINOSQBMSLE-JOCHJYFZSA-N
InChI: InChI=1S/C27H24N4O2S/c32-22-11-12-30(15-22)14-21-17-34-27-29-25(16-31(21)27)23-7-3-4-8-24(23)28-26(33)20-10-9-18-5-1-2-6-19(18)13-20/h1-10,13,16-17,22,32H,11-12,14-15H2,(H,28,33)/t22-/m1/s1
Canonical SMILES: O=C(Nc1ccccc1-c1cn2c(CN3CCC(O)C3)csc2n1)c1ccc2ccccc2c1
Isomeric SMILES: C1CN(C[C@@H]1O)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=CC6=CC=CC=C6C=C5

Synonyms

SRT 2183
(R)-N-(2-(3-((3-hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide
N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide
2-Naphthalenecarboxamide, N-(2-(3-(((3R)-3-hydroxy-1-pyrrolidinyl)methyl)imidazo(2,1-b)thiazol-6-yl)phenyl)-
N-(2-(3-(((3R)-3-Hydroxy-1-pyrrolidinyl)methyl)imidazo(2,1-b)thiazol-6-yl)phenyl)-2-naphthalenecarboxamide
2-Naphthalenecarboxamide, N-[2-[3-[[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]-
N-(2-(3-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl)naphthalene-2-carboxamide
SRT 2183, 10 mM in DMSO
Inhibitor,Sirtuin,Apoptosis,SRT-2183,SRT 2183,inhibit,SRT2183
(R)-N-[2-[3-[(3-Hydroxy-1-pyrrolidinyl)methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]-2-naphthamide
N-[2-(3-{[(3R)-3-Hydroxy-1-pyrrolidinyl]methyl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-naphthamide
N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]naphthalene-2-carboxamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight	468.58 g/molcalc.
Exact mass	468.162 Dacalc.
LogP (octanol/water)	5.03calc.
Topological polar surface area	69.87 Å²calc.
Hydrogen bond donors	2calc.
Hydrogen bond acceptors	5calc.
Rotatable bonds	5calc.
Heavy atoms	34calc.
Rings	6calc.
Aromatic rings	5calc.
Fraction sp3 carbons	0.19calc.
Formal charge	0calc.
Stereocentres	1calc.
Lipinski rule of five	Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

O=C(Nc1ccccc1-c1cn2c(CN3CCCC3)csc2n1)c1ccc2ccccc2c1

6 rings, 33 atoms.

1 other chemical share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Srt-2183 suppliers

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Srt-2183 price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Srt-2183 is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024

$26.7B

+15.0% vs 2023, imports $26.3B

2019 to 2024

Top exporters

Ireland26.3%
China15.7%
Singapore10.3%

Top importers

Reported customs values in USD, not prices.Full trade data

The HS code shown for Srt-2183 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Parent and salt forms, stereoisomers, similar structures and isomers

Salt and hydrate forms

Records that share this compound as their parent

(R)-N-(2-(3-((3-Hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide hydrochloride chemical structure, C27H25ClN4O2S, CAS 1956436-86-4

(R)-N-(2-(3-((3-Hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide hydrochloride1956436-86-4C₂₇H₂₅ClN₄O₂S

Similar structures

Nearest neighbours by Morgan fingerprint Tanimoto similarity

3,4-Dimethoxy-N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]benzamide chemical structure, C25H27N5O3S, CAS 925432-72-0

3-Methoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide chemical structure, C24H25N5O2S, CAS 925437-59-8

Same formula isomers

Different compounds that share this molecular formula

All isomers

N-Benzyl-N-ethyl-2-({3-oxo-2-phenyl-2H,3H-imidazo[1,2-c]quinazolin-5-yl}sulfanyl)acetamide chemical structure, C27H24N4O2S, CAS 957247-08-4

N-Benzyl-N-ethyl-2-({3-oxo-2-phenyl-2H,3H-imidazo[1,2-c]quinazolin-5-yl}sulfanyl)acetamide957247-08-4C₂₇H₂₄N₄O₂S

2-[[3-(3,5-Dimethylphenyl)-4-oxo-5H-pyrimido[5,4-b]indol-2-yl]sulfanyl]-N-(3-methylphenyl)acetamide chemical structure, C27H24N4O2S, CAS 536705-51-8

2-[[3-(3,5-Dimethylphenyl)-4-oxo-5H-pyrimido[5,4-b]indol-2-yl]sulfanyl]-N-(3-methylphenyl)acetamide536705-51-8C₂₇H₂₄N₄O₂S

N-(4-Ethylphenyl)-2-[[3-(4-methylphenyl)-4-oxo-5H-pyrimido[5,4-b]indol-2-yl]sulfanyl]acetamide chemical structure, C27H24N4O2S, CAS 536704-82-2

N-(4-Ethylphenyl)-2-[[3-(4-methylphenyl)-4-oxo-5H-pyrimido[5,4-b]indol-2-yl]sulfanyl]acetamide536704-82-2C₂₇H₂₄N₄O₂S

2-((2-Benzyl-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)thio)-N-(3,4-dimethylphenyl)acetamide chemical structure, C27H24N4O2S, CAS 959528-82-6

2-((2-Benzyl-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)thio)-N-(3,4-dimethylphenyl)acetamide959528-82-6C₂₇H₂₄N₄O₂S

2-((2-Benzyl-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)thio)-N-(2-ethylphenyl)acetamide chemical structure, C27H24N4O2S, CAS 959505-03-4

2-((2-Benzyl-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)thio)-N-(2-ethylphenyl)acetamide959505-03-4C₂₇H₂₄N₄O₂S

2-[(2-Benzyl-3-oxo-2H-imidazo[1,2-c]quinazolin-5-yl)sulfanyl]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C27H24N4O2S, CAS 957626-48-1

2-[(2-Benzyl-3-oxo-2H-imidazo[1,2-c]quinazolin-5-yl)sulfanyl]-N-[(4-methylphenyl)methyl]acetamide957626-48-1C₂₇H₂₄N₄O₂S

(Z)-N-(3-Oxo-1-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)-3-(pyrrolidin-1-yl)prop-1-en-2-yl)benzamide chemical structure, C27H24N4O2S, CAS 1017660-87-5

(Z)-N-(3-Oxo-1-(1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)-3-(pyrrolidin-1-yl)prop-1-en-2-yl)benzamide1017660-87-5C₂₇H₂₄N₄O₂S

$N-(2,5-Dimethylphenyl)-2-[11-(3,4-dimethylphenyl)-6-oxo-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-5-yl]acetamide chemical structure, C27H24N4O2S, CAS 1112332-12-3$

N-(2,5-Dimethylphenyl)-2-[11-(3,4-dimethylphenyl)-6-oxo-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-5-yl]acetamide1112332-12-3C₂₇H₂₄N₄O₂S

N-Benzyl-2-((3-(3,5-dimethylphenyl)-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-yl)thio)acetamide chemical structure, C27H24N4O2S, CAS 536705-78-9

N-Benzyl-2-((3-(3,5-dimethylphenyl)-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-yl)thio)acetamide536705-78-9C₂₇H₂₄N₄O₂S

2-({2-Benzyl-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-5-yl}sulfanyl)-N-(4-ethylphenyl)acetamide chemical structure, C27H24N4O2S, CAS 1022198-67-9

2-({2-Benzyl-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-5-yl}sulfanyl)-N-(4-ethylphenyl)acetamide1022198-67-9C₂₇H₂₄N₄O₂S

2-((4-Oxo-3-(p-tolyl)-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-yl)thio)-N-phenethylacetamide chemical structure, C27H24N4O2S, CAS 536704-86-6

2-((4-Oxo-3-(p-tolyl)-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-yl)thio)-N-phenethylacetamide536704-86-6C₂₇H₂₄N₄O₂S

N-Benzyl-2-({1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1H-benzimidazol-2-yl}thio)acetamide chemical structure, C27H24N4O2S, CAS 1115490-87-3

N-Benzyl-2-({1-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1H-benzimidazol-2-yl}thio)acetamide1115490-87-3C₂₇H₂₄N₄O₂S

Frequently asked questions

Quick answers about Srt-2183, based on the data on this page

What is Srt-2183?

Srt-2183 is a chemical substance with the molecular formula C27H24N4O2S and a molar mass of 468.58 g/mol. Its CAS registry number is 1001908-89-9. The IUPAC name is N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide.

What is the CAS number of Srt-2183?

The CAS registry number of Srt-2183 is 1001908-89-9.

What is the molecular formula and weight of Srt-2183?

The molecular formula of Srt-2183 is C27H24N4O2S and its molar mass is 468.58 g/mol.

What is Srt-2183 used for?

Known uses and roles of Srt-2183 include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Srt-2183 hazardous?

No GHS hazard classification for Srt-2183 is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Srt-2183?

Srt-2183 is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Srt-2183?

Post a free request on CompoundList and suppliers of Srt-2183 will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Srt-2183?

Suppliers quote Srt-2183 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Srt-2183

Key facts

What is Srt-2183?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Srt-2183 suppliers

Srt-2183 price

Uses and applications

Industries and functions

Regulatory status

HS code and trade data

Global trade

Frequently asked questions

What is Srt-2183?

What is the CAS number of Srt-2183?

What is the molecular formula and weight of Srt-2183?

What is Srt-2183 used for?

Is Srt-2183 hazardous?

What is the HS code of Srt-2183?

Where can I buy Srt-2183?

What is the price of Srt-2183?

Guides for buyers

Get quotes for Srt-2183

Key facts

What is Srt-2183?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

Srt-2183 suppliers

Srt-2183 price

Uses and applications

Industries and functions

Regulatory status

HS code and trade data

Global trade

Related chemicals

Salt and hydrate forms

Similar structures

Same formula isomers

Frequently asked questions

What is Srt-2183?

What is the CAS number of Srt-2183?

What is the molecular formula and weight of Srt-2183?

What is Srt-2183 used for?

Is Srt-2183 hazardous?

What is the HS code of Srt-2183?

Where can I buy Srt-2183?

What is the price of Srt-2183?

Guides for buyers

Get quotes for Srt-2183