CompoundList
Sign in
Alkaloids

Stylopine

Also known as (S)-Stylopine, (-)-Tetrahydrocoptisine, l-Tetrahydrocoptisine

CAS 84-39-9Formula C19H17NO4Molar mass 323.35 g/molEC 884-572-4
Get quotes Safety data
Stylopine chemical structure, C19H17NO4, CAS 84-39-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
84-39-9
Formula
C19H17NO4
Molar mass
323.35 g/mol
EC number
884-572-4
HS code
293979
Category
Alkaloids

What is Stylopine?

Plain description, key identifiers and synonyms

(S)-stylopine is a berberine alkaloid isolated from the plants of the family papaveraceae. It has a role as a plant metabolite. It is an an (S)-7,8,13,14-tetrahydroprotoberberine, a berberine alkaloid and an organic heterohexacyclic compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1S)-5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-2,4(8),9,15(23),16(20),21-hexaene
CAS number
84-39-9 CAS number cross-checkedOther or deprecated CAS: 7461-02-1
EC number
884-572-4
Molecular formula
C19H17NO4
InChIKey
UXYJCYXWJGAKQY-HNNXBMFYSA-N
InChI
InChI=1S/C19H17NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,6-7,15H,3-5,8-10H2/t15-/m0/s1
Canonical SMILES
c1cc2c(c3c1CC1c4cc5c(cc4CCN1C3)OCO5)OCO2
Isomeric SMILES
C1CN2CC3=C(C[C@H]2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6

Synonyms

  • (S)-Stylopine
  • (-)-Tetrahydrocoptisine
  • l-Tetrahydrocoptisine
  • (12bS)-6,7,12b,13-tetrahydro-2H,4H,10H-[1,3]dioxolo[4,5-g][1,3]dioxolo[4',5':7,8]isoquino[3,2-a]isoquinoline
  • 6,7,12b,13e-Tetrahydro-4H-bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizine
  • 6,7,12b,13e-Tetrahydro-4H-bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizine
  • (12bS)-6,7,12b,13-tetrahydro-2H,4H,10H-(1,3)dioxolo(4,5-g)(1,3)dioxolo(4',5':7,8)isoquino(3,2-a)isoquinoline
  • stylopine, (S)-isomer
  • 2,3:9,10-Bis(methylenedioxy)-(-)-tetrahydroberberine
  • 4H-Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizine, 6,7,12b,13-tetrahydro-, (12bs)-
  • 13Aalpha-BERBINE, 2,3:9,10-BIS(METHYLENEDIOXY)-
  • (12bS)-6,7,12b,13-Tetrahydro-4H-bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizine
  • 6, 7, 12b, 13e-tetrahydro-4H-bis (1, 3)benzodioxolo(5, 6-a:4', 5'-g) quinolizine
  • (-)-Stylopine
  • (1S)-5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-2,4(8),9,15(23),16(20),21-hexaene
  • 2,3:9,10-Bis(methylenedioxy)-13a-alpha-berbine
  • Stylopine, (+/-)-(p)
  • 4H-Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizine, 6,7,12b,13-tetrahydro-, (S)-
  • (-)-Stylopine (Tetrahydrocoptisine)
  • 6, 7, 12b, 13e-tetrahydro-4H-bis [1, 3]benzodioxolo[5, 6-a:4' , 5' -g] quinolizine
  • (12bS)-6,7,12b,13-Tetrahydro-2H,4H,10H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinoline

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
323.35 g/molcalc.
Exact mass
323.1158 Dacalc.
LogP (octanol/water)
2.8calc.
Topological polar surface area
40.16 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
0calc.
Heavy atoms
24calc.
Rings
6calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.37calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1cc2c(c3c1CC1c4cc5c(cc4CCN1C3)OCO5)OCO2

c1cc2c(c3c1CC1c4cc5c(cc4CCN1C3)OCO5)OCO2

6 rings, 24 atoms, the (±)-Stylopine ring system.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Stylopine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

No supplier listings yet

Post one free request and suppliers who make or trade Stylopine can send you quotes. Your contact details stay private until you accept a quote.

Request quotesSell this chemical

Stylopine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Roles

  • eukaryotic metabolite
  • metabolite
  • plant metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Stylopine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Stylopine is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Stylopine, based on the data on this page

What is Stylopine?

(S)-stylopine is a berberine alkaloid isolated from the plants of the family papaveraceae. It has a role as a plant metabolite. It is an an (S)-7,8,13,14-tetrahydroprotoberberine, a berberine alkaloid and an organic heterohexacyclic compound.

What is the CAS number of Stylopine?

The CAS registry number of Stylopine is 84-39-9. Other or deprecated CAS numbers: 7461-02-1.

What is the molecular formula and weight of Stylopine?

The molecular formula of Stylopine is C19H17NO4 and its molar mass is 323.35 g/mol.

What is Stylopine used for?

Known uses and roles of Stylopine include eukaryotic metabolite, metabolite and plant metabolite.

Is Stylopine hazardous?

No GHS hazard classification for Stylopine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Stylopine?

Stylopine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Stylopine?

Post a free request on CompoundList and suppliers of Stylopine will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Stylopine?

Suppliers quote Stylopine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Stylopine

Get quotes for Stylopine

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Stylopine
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Stylopine with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/stylopine-84-39-9" title="Stylopine structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Alkaloids or HS code 293979

Price on request
Free quotes, contact stays private
Get quotes