Tricalcium phosphate
Also known as Synthos, Calcium orthophosphate, Tricalcium diphosphate
Key facts
What buyers check first
- Appearance
- White amorphous powder
- Melting point
- 1,670 °C
- Density
- 3.14 g/cm³
- Solubility
- Solubility in cold water: 2 mg/100 cc
- HS code
- 283526
- Category
- Phosphates and phosphorus salts

What is Tricalcium phosphate?
Plain description, key identifiers and synonyms
Tricalcium bis(phosphate) is a calcium phosphate.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- tricalcium diphosphate
- CAS number
- 7758-87-4 CAS number cross-checkedOther or deprecated CAS: 10103-46-5, 21063-37-6
- EC numbers
- 231-840-8, 233-283-6
- Molecular formula
- Ca3O8P2
- UNII
- K4C08XP666
- MDL number
- MFCD00015984
- INCI name
- TRICALCIUM PHOSPHATE
- InChIKey
- QORWJWZARLRLPR-UHFFFAOYSA-H
- InChI
- InChI=1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6
- SMILES (canonical and isomeric)
- [O-]P(=O)([O-])[O-].[O-]P(=O)([O-])[O-].[Ca+2].[Ca+2].[Ca+2]
Synonyms
- Synthos
- Calcium orthophosphate
- Tricalcium diphosphate
- Phosphoric acid, calcium salt (2:3)
- Tricalcium orthophosphate
- Calcigenol simple
- Tertiary calcium phosphate
- Bonarka
- Calcium phosphate, tribasic
- Calcium tertiary phosphate
- Calcium phosphate (3:2)
- Natural whitlockite
- Calcium phosphate (Ca3(PO4)2)
- Calcium orthophosphate, tri-(tert)
- Tricalcium phosphate (Ca3(PO4)2)
- Phosphoric acid calcium(2+) salt (2:3)
- INS NO.341(III)
- INS-341(III)
- E-341(III)
- Bone powder, purified
- calcium phosphate, tricalcium salt
- Phosphoric acid, calcium salt (2:3), Ca3(PO4)2
- Calcium phosphate tribasic
- Calcium phosphate
- beta-TCP
Show all 38 synonymsShow fewer synonyms
- Cerasorb
- Synthograft
- beta-Tricalcium phosphate
- OSferion
- tricalcium, diphosphate
- Ceredex
- Multifos
- Vitoss
- TricOs
- Calipharm T
- Tricafos P
- Phosphoric acid, calcium salt
- JAX TCP
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | White amorphous powderexp.Measured value |
|---|---|
| Odour | Odorlessexp.Measured value |
| Taste | Tastelessexp.Measured value |
| Melting point | 1,670 °Cexp.Measured value |
| Density | 3.14 g/cm³exp.Measured value |
| Solubility | Solubility in cold water: 2 mg/100 ccexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 310.17 g/molcalc.Computed value |
|---|---|
| Exact mass | 309.7946 Dacalc.Computed value |
| LogP (octanol/water) | -6.79calc.Computed value |
| Topological polar surface area | 172.5 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 8calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 13calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Components | 5calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H318Causes serious eye damage.
Precautionary statements (4)
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317Get medical help.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidTricalcium phosphate suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, Indore ManufacturerUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- China, Shijiazhuang ManufacturerUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- China, Lianyungang ManufacturerUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- China, Changshu ManufacturerUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- China, Changsha ManufacturerUnclaimed profileCalcium Phosphate TribasicGrade, purity and minimum order on requestPrice on request
- Belgium, AartselaarUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileCalcium phosphate tribasicGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- India, Valsad ManufacturerUnclaimed profileTricalcium PhosphateGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileCalcium phosphate, tribasicGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
238 suppliers in 39 countries
- China61
- United States51
- India40
- Germany10
- United Kingdom9
- Spain6
- and 33 more countries
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Tricalcium phosphate price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Manuf of fertilizers, H3PO4 and P compds, manuf milk-glass, polishing and dental powders, porcelains, pottery, enameling, clarifying sugar syrups, in animal feeds, as noncaking agent, in the textile industry.
Stabilizer for plastics, in meat tenderizers, in food as buffer.
Therapeutic category: Calcium replenisher.
Therapeutic category (veterinary): Has been used as a dietary supplement, and as an antacid.
Industrial uses: Lubricating agent, Corrosion inhibitor, Soil amendments (fertilizers), Filler, Intermediate.
Consumer uses: Corrosion inhibitor, Pigment, Lubricating agent, Intermediate, Filler.
Use classes: Food additives, Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name TRICALCIUM PHOSPHATE(abrasive, anticaking, fragrance, opacifying)
Pharmacological actions
- Biocompatible Materials
Functional uses
- Abrasive
- Anti-caking agent
- Deodorizer
- Drier
- Emulsifier
- Filler
- Flavouring and nutrient
- Fragrance
- Humectant
- Leavening agent
- Opacifer
- pH regulating agent
Cosmetic functions
- Abrasive
- Anticaking
- Fragrance
- Opacifying
- Oral care
Pharmacology
Calcium Phosphate is the calcium salt of phosphoric acid with widely used applications. This agent can be used as a countermeasure for exposure to strontium and radium radionuclides. Upon oral uptake, calcium phosphate competes for and blocks the absorption of radium (Ra-226) and strontium (Sr-90) in the gastrointestinal (GI) tract.
How it is made
High temperature reaction of phosphate rock, silica, wet-process phosphoric acid, & soda ash (feed-grade), reaction of furnace phosphoric acid & calcium oxide or calcium nitrate (food-grade)
(Animal) bones are calcined until white, then ground & digested with hydrochloric acid (or sulfuric acid)... After filtration, solution is treated either with ammonia or more generally with calcium hydroxide whereby calcium phosphate is ppt. (Tribasic calcium phosphate NF)
By interaction of solutions of calcium chloride & sodium triphosphate with excess of ammonia.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Food additive
United States
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Tricalcium phosphate is traded under.
Phosphates, other phosphates of calcium
- China25.6%
- Morocco14.2%
- United States8.6%
- United States10.8%
- Germany7.5%
- Netherlands5.6%
The HS code shown for Tricalcium phosphate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Tricalcium phosphate, based on the data on this page
What is Tricalcium phosphate?
What is the CAS number of Tricalcium phosphate?
What is the molecular formula and weight of Tricalcium phosphate?
What is Tricalcium phosphate used for?
Is Tricalcium phosphate hazardous?
What is the HS code of Tricalcium phosphate?
Where can I buy Tricalcium phosphate?
Where can I buy Tricalcium phosphate in India?
What is the price of Tricalcium phosphate?
Guides for buyers
Practical guides that help when you source, ship or handle Tricalcium phosphate
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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